A5042216057- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Adolescent and Pediatric Healthcare
- Electroconvulsive Therapy Studies
- Treatment of Major Depression
- Tryptophan and brain disorders
- Dementia and Cognitive Impairment Research
- Neurological Disorders and Treatments
- Advanced MRI Techniques and Applications
- NMR spectroscopy and applications
- Family Support in Illness
- Advanced Neuroimaging Techniques and Applications
- Autoimmune Neurological Disorders and Treatments
- Electrolyte and hormonal disorders
- Healthcare Decision-Making and Restraints
- Neurological Disease Mechanisms and Treatments
- Psychosomatic Disorders and Their Treatments
- Diagnosis and Treatment of Venous Diseases
- Obsessive-Compulsive Spectrum Disorders
- Pregnancy and Medication Impact
- Ethics and Legal Issues in Pediatric Healthcare
- Acne and Rosacea Treatments and Effects
- Alzheimer's disease research and treatments
- Suicide and Self-Harm Studies
Bahçeşehir University
2020-2025
Istanbul University
2010-2024
The University of Texas Health Science Center at San Antonio
2006
Adli Tıp Kurumu
2005
Background: Although bipolar disorder and schizophrenia have long been viewed as distinct illnesses, there is growing evidence that these two complex diseases share some common genes, which may manifest overlapping neuropsychological impairments. working memory dysfunction has proposed to be central the pathophysiology of schizophrenia, it received less attention in studies disorder. Method: We applied measures patients with (n = 15), schizoaffective psychotic 11) non‐psychotic 15) disorder,...
The aim of the present study was to investigate potential influence childhood trauma on clinical presentation, psychiatric comorbidity, and long-term treatment outcome bipolar disorder. A total 135 consecutive patients with disorder type I were recruited from an ongoing prospective follow-up project. Childhood Trauma Questionnaire Structured Clinical Interview for DSM–IV Axis Disorders administered all participants. Response determined records life charts There no significant differences in...
Abstract Purpose To improve prescribing in older adults, criterion sets have been introduced from different countries. While current are useful to some extent, they do not meet the need European Turkish inappropriate medication use elderly (TIME) criteria was planned this need. Methods In phase 1, user friendly sets: STOPP/START version2 and CRIME were combined. National experts composed of geriatricians non-geriatricians invited review comment. 2, thorough literature performed...
Objectives This study aimed to investigate the effectiveness of social cognition and interaction therapy (SCIT) in improving occupational functioning individuals diagnosed with bipolar disorder I (BD-I). The effects SCIT intervention standard treatment methods were investigated on effects, which are often negatively affected patients BD-I. Methods research involved 28 participants, allocated into two groups: An experimental group ( n = 12) receiving for 8 weeks alongside treatments...
Tetracycline derivatives provide moderate benefit in the treatment of ocular rosacea. Recently, azithromycin has been found to be an effective alternative cutaneous papulopustular rosacea.We planned a study evaluate effects on symptoms, signs and tear function tests rosacea patients.An open-labelled was performed population 20 patients.Eighteen subjects completed trial. Significant improvement seen eyelid findings conjunctival hyperaemia scores (P = 0.002, P < 0.0001, 0.005, respectively)....
Introduction: Venous balloon dilation and stent therapy have been proposed as effective treatments for chronic iliofemoral thrombosis. In this study, we report our experience describe the one-year outcome efficacy of angioplasty stenting treatment post-thrombotic syndrome (PTS) in vein segments. Methods: From June 2011 to 2012, 52 consecutive patients with PTS (59 limbs; 75% women; median age 58 years; range: 23–76 years) referred unit interventional assessment were included study. Treatment...
Bipolar disorder (BD) patients have recently been shown to exhibit increased proinflammatory cytokine levels indicating the role of inflammation in this disease. As inflammatory responses often include complement level alterations and production is influenced by cytokines, we aimed find out whether system activated BD a time-dependent manner factors are involved pathogenesis.Serum C4, factor B, sC5b-9 neuron-specific enolase were measured enzyme-linked immunosorbent assay, whereas peripheral...
Anti-neuronal autoimmunity may cause cognitive impairment that meets the criteria for dementia. Objective. Our aim was to detect incidence and clinical features of autoimmune encephalitis imitating findings primary dementia disorders delineate validity anti-neuronal antibody screening in patients.Fifty consecutive patients fulfilling dementia, 130 control patients, 50 healthy controls were included. Their sera investigated several ion channel glutamic acid decarboxylase (GAD) antibodies by a...
Agitation is one of the most devastating behavioral symptoms in demented patients but there little evidence about effective and safe pharmacotherapy. We aimed to determine effectiveness safety mirtazapine treatment agitated with Alzheimer's disease (AD). The consecutive AD who have significant agitation were assigned a 12-week open-label, prospective study. Patients received 15-30 mg/day. changes Cohen-Mansfield Inventory-Short form (CMAI-SF) scores primary outcome measurement. change...
In this study, we aimed to compare the clinical features and response patterns long-term prophylaxis of bipolar patients with or without psychotic features.The life charts I disorder were evaluated. Two hundred eighty-one who suffer for at least 4 years had three mood episodes included study. The whose all are (psychotic group) never experienced episode (non-psychotic assigned as comparison groups. compared across groups.The group consists 43 patients; non-psychotic 54 patients. history...
Abstract The aim of this study was to investigate the association between T102C polymorphism on 5HT2A gene and cognitive function as well clinical manifestations in patients with schizophrenia. Eighty‐two outpatients schizophrenia participated study. Brief Psychiatric Rating Scale (BPRS) used assess severity each patient's symptoms. In order evaluate their short‐term attention capacity, a Digit Span Test used. Continuous Performance (CPT) test sustained span subjects. Cognitive flexibility...
<b>BACKGROUND AND PURPOSE:</b> The callosal disconnectivity theory was previously proposed to explain the pathophysiology of schizophrenia. goal this study investigate metabolic integrity corpus callosum in patients with schizophrenia by proton MR spectroscopy. <b>MATERIALS METHODS:</b> Twelve first-episode and 16 chronic meeting <i>Diagnostic Statistical Manual Mental Disorders (DSM-IV)</i> criteria for 28 age- sex-matched control subjects were enrolled study. We measured absolute...
The increase in the circulatory cytokine levels observed patients with bipolar disorder (BD) may imply involvement of inflammation pathogenesis mood disorders. However, association between inflammatory process and stage severity illness is not well understood. In this study, our aim was to investigate neuroinflammation disease progression clinical course BD.IL-6, TNF-α, IL-1 receptor antagonist (IL-1RA), neuronspecific enolase (NSE) S100B were measured by ELISA plasma samples at early-stage...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Electroconvulsive therapy (ECT) is known to be an effective option in the treatment of mood disorders, especially resistant depression. However, remission achieved by ECT was reported not long lasting enough. The aim present study investigate relapse/recurrence rates and associated risk factors during first year after patients diagnosed with disorders.In a naturalistic observation, unipolar depressive disorder or episode bipolar who had were followed up for at least one year. evaluated...
Second-generation antipsychotics (SGAs) have been used in the augmentation of treatment-resistant depression. However, little is known about their effectiveness, tolerability, and adverse events treatment late-life depression, which were aim this study.The retrospective data patients aged >65 years who had a major depressive episode with inadequate response to antidepressant adjuvant SGA analyzed. The outcome measures number continued use SGAs fourth twelfth weeks, events, changes symptoms...
The recurrent nature of bipolar disorder needs an optimum compliance with long term pharmacotherapy, however the poor adherence is common. Adjunctive psychoeducation seems favorable effects on during pharmacotherapy. Even strong benefits were showed, setting a in clinical practice still novel and recruiting patients history may not be feasible. In literature, recruitment rate, motivation attitudes for participation studied. present study was conducted to clarify intends participate factors...