A5011325825- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Infection Control and Ventilation
- Ginkgo biloba and Cashew Applications
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Acupuncture Treatment Research Studies
- Nosocomial Infections in ICU
- Pediatric Pain Management Techniques
- Adenosine and Purinergic Signaling
- Advanced Glycation End Products research
- Blood donation and transfusion practices
- Mechanical Circulatory Support Devices
- History and Cultural Heritage
- Streptococcal Infections and Treatments
- Neonatal Respiratory Health Research
- Phagocytosis and Immune Regulation
- Airway Management and Intubation Techniques
- Thermal Regulation in Medicine
- Cultural and Sociopolitical Studies
- Cardiac Arrest and Resuscitation
- Family and Patient Care in Intensive Care Units
Istanbul University
2020-2025
Türk Anesteziyoloji ve Reanimasyon Derneği
2020-2023
Türkisch-Deutsche Universität
2021-2023
Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi
2020
Sağlık Bilimleri Üniversitesi
2020
Background/Aim: Sepsis-induced acute kidney injury is a fatal, potentially reversible clinical condition. C5a receptor (C5aR) has been implied to play pivotal roles in both autophagy and sepsis-induced organ dysfunction. The aim of this study was demonstrate the effects intravenous immunoglobulin preparations on expression markers investigate possible association between C5aR tissue septic rats. Materials Methods: Sepsis induced by cecal ligation perforation (CLP) rats, which were divided...
Objective:The defective interplay between coagulation and inflammation may be the leading cause of intravascular organ dysfunction in coronavirus disease-19 (COVID-19) patients.Abnormal profiles were reported to associated with poor outcomes.In this study, we assessed prognostic values antithrombin (AT) activity levels impact fresh frozen plasma (FFP) treatment on outcome. Materials Methods:Conventional parameters as well AT outcomes 104 consecutive critically ill acute respiratory distress...
Objectives To evaluate the effect of adjunct treatment with Octagam, an intravenous immunoglobulin (IVIG) product, on clinical outcomes and biomarkers in critically ill COVID-19 patients.
Abstract Introduction Acute kidney injury (AKI) is linked to disease severity and prognosis in patients with coronavirus 2019 (COVID-19), mortality increases even milder stages. This study primarily investigated the effects of continuous renal replacement therapy (CRRT) timing on intensive care unit (ICU) COVID-19 acute respiratory distress syndrome (ARDS) AKI. Secondary goals were secondary for ICU, days without life support treatment, change post-CRRT day biomarker levels, length ICU...
The information on electrocardiographic features of patients with coronavirus disease 2019 (COVID-19) is limited. Our aim was to determine if baseline hospitalized COVID-19 are associated markers myocardial injury and clinical outcomes.In this retrospective, single center cohort study, we included 223 laboratory-confirmed COVID-19. Clinical, laboratory data were collected analyzed. Primary composite endpoint mortality, need for invasive mechanical ventilation, or admission the intensive care...
Viral load varies during infection and is higher the initial stages of disease. Given importance intensive care unit (ICU) in late COVID-19 infection, analyzing cycle threshold values to detect viral upon ICU admission can be a clinically valuable tool for identifying patients with highest mortality risk.This was retrospectively designed study. Patients older than 18 years who tested positive SARS-CoV-2 PCR had PaO2/FiO2 ratio <200 were included The patient population divided into two...
Abstract Background: There is some evidence from case reports and a few studies in China that critically ill COVID-19 patients may benefit treatment with intravenous immunoglobulins (IVIG). We compared clinical outcomes biomarkers Turkish cohort of severe who were treated the institution's standard care (SOC), either alone or combination IVIG. Methods: Data two intensive units at University hospital Istanbul was analyzed retrospectively. Patients received preliminary SOC according to...
Objective: In November 2019, an outbreak of coronavirus disease-2019 caused by SARS-CoV-2, a new type from Wuhan, China, was reported.The risk factors affecting mortality are still not clearly defined.This study aimed to determine the effect gender on inflammatory markers in COVID-19 patients who were admitted intensive care unit (ICU).Materials and Methods: Data 90 ICU Istanbul Medical Faculty Hospital between March 18, 2020 May 30, 2020, retrospectively reviewed.Demographic, clinical,...
Abstract Background Coronavirus disease- 2019 (COVID-19) related to acute respiratory distress syndrome (ARDS) caused by the highly infectious SARS-CoV-2 novel coronavirus is a major cause of death during pandemic period. Here we aim present retrospective data analysis extubation success High Flow Nasal Cannula Oxygen Therapy (HFNO) in COVID-19 ARDS patients. Methods The 22 laboratory-confirmed patients who were extubated HFNO therapy at an intensive care unit (ICU) analyzed. Respiratory...
ÖZ Amaç: Aşırı inflamasyona bağlı hiperkoagülopati, koronavirüs hastalığı-19 (COVID-19) hastalarında mortalite ve organ yetmezliğinden sorumlu olabilir.Anormal pıhtılaşma profilleri, kötü sonlanımlarla ilişkilendirilmiştir. Bu çalışmada, yoğun bakım ünitesine (YBÜ) kabul edilen kritik COVID-19 antitrombin (AT) düzeylerinin prognostik değerini değerlendirmeyi
Training and Research Hospital.Available on-line
Case PresentationAll patients were male with a mean age of 48.8 (36-68) years and body mass index (BMI) 35 (31.1-38.9).The time between symptom initiation to intensive care unit (ICU) admission was 9.5 days, the Acute Physiology Chronic Health Evaluation (APACHEII) median Sepsis-Related Organ Failure Assessment (SOFA) scores on ICU 19.16 (24-16) 7.3 (5-10), respectively.The comorbidities were: 1 patient hypertension, 2 diabetes, coronary artery disease.ECMO started relatively early after...
Objective: The acute respiratory distress syndrome (ARDS)-associated coronavirus disease-2019 , caused by the highly contagious severe 2 novel coronavirus, is a major cause of death during pandemic period.Here, we aim to present retrospective data analysis success extubation high-flow nasal oxygen (HFNO) among COVID-19 ARDS patients.Materials and Methods: 22 patients who were laboratory confirmed extubated on HFNO while under intubation in intensive care unit (ICU) analyzed.Respiratory...
Objective: Our study aimed to compare the mini-bronchoalveolar lavage (mini-BAL) method with classical methods of endotracheal aspiration (ETA) and BAL in patients followed up intensive care unit (ICU) diagnosed nosocomial pneumonia.Materials Methods: comprised 30 who were a suspicion ventilator-associated pneumonia (VAP) between February 2014 January 2015 at İstanbul University, Faculty Medicine, Department Anesthesiology Reanimation, ICU.Results: A total 40% (12 people) women, 60% (18 men,...