- Parasitic Infections and Diagnostics
- Amoebic Infections and Treatments
- Reproductive tract infections research
- Toxoplasma gondii Research Studies
- Viral gastroenteritis research and epidemiology
- Helicobacter pylori-related gastroenterology studies
- Cytomegalovirus and herpesvirus research
- HIV Research and Treatment
- COVID-19 Clinical Research Studies
- Herpesvirus Infections and Treatments
- MicroRNA in disease regulation
- Long-Term Effects of COVID-19
- Hepatitis B Virus Studies
- Respiratory viral infections research
- Helminth infection and control
- Genital Health and Disease
- Hepatitis C virus research
- HIV/AIDS Research and Interventions
- Parvovirus B19 Infection Studies
- Parasites and Host Interactions
- Rabies epidemiology and control
- Asthma and respiratory diseases
- Cancer-related molecular mechanisms research
- SARS-CoV-2 detection and testing
- Pediatric health and respiratory diseases
Istanbul University
2013-2025
This study aimed to evaluate the performance characteristics of a rapid antigen test developed detect SARS-CoV-2 (COVID-19), influenza A virus (IAV), and B (IBV) (flu) compared with those real-time reverse transcription-polymerase chain reaction (rRT-PCR) method. One hundred SARS-CoV-2, one IAV, twenty-four IBV patients whose diagnoses were confirmed by clinical laboratory methods included in patient group. Seventy-six patients, who negative for all respiratory tract viruses, as control The...
Background/Objectives: T. pallidum subsp. is a spirochete that only causes disease in humans as the causative agent of syphilis. HIV and syphilis have common transmission routes. In present study, our aim was to evaluate presence coinfection people living with using conventional reverse algorithms investigate its effects on laboratory parameters. Methods: The traditional algorithm for begins testing non-treponemal test. If test reactive, treponemal then used confirm infection. this...
New rapid, reliable, and cost-effective alternative systems are needed for the rapid diagnosis of Streptococcus pyogenes. The aim this study was to fabricate a microfluidic test device detect pyogenes by combining Loop-mediated isothermal amplification method via 3D printer. Microfluidic devices were designed in CATIA V5 Release 16 software, data directly transferred printer produced using FDM with biocompatible PLA filament. S. ATCC 19615 different strains used. Following identification...
We aimed to investigate the presence of three recently identified point mutations (A2115G, G2141A and A2144T) 23 S rRNA gene compare them with most frequently encountered (A2142G, A2142C A2143G) in Helicobacter pylori strains Turkey.A total 63 patients (mean 47.08±12.27) were included. The E-test method (for clarithromycin) was used for clarithromycin antimicrobial susceptibility test isolated H. strains. Real-time PCR detect mutations.A 24 out (38.1%) detected as resistant (>0.5 mg l-1 )....
Cystic echinococcosis is one of the most important zoonotic diseases in Turkey. The aim this study was for molecular analysis of Echinococcus granulosusisolates from different regions For purpose, 46 hydatid cyst samples collected humans during surgery were included. partial sequences mitochondrial cytochrome c oxidase subunit 1 (CO1) gene used identification and of E. granulosus strains. Molecular showed that all human cysts belonged to G1 genotype (common sheep strain) granulosus....
Amaç: Bu çalışma, Avrupa ve Asya'nın ortak coğrafik özelliklerine
Among sexually transmitted diseases, HIV causes very serious clinical manifestations that can lead to death. As a result, millions of people have live with this problem threatens their health. The virus attacks the immune system host, especially CD4+ T lymphocytes, causing suppression system. CD4, CD8 counts, and RNA viral loads are monitored in HIV-infected patients antiretroviral treatment, CD4 counts play an important role determining effectiveness treatment. Despite advances treatment...
A 51-year-old woman who lives in northeastern Turkey presented with diminished vision the right eye a 1-year duration. On examination, best corrected visual acuity was 2/10 and 10/10 left eye. The slit-lamp examination of anterior segment revealed no significant findings either Intraocular pressure within normal limits. Ophthalmoscopic disclosed slender motile parasite held on Weiss ring old multiple chorioretinitis foci …
Background We aimed to evaluate the roles of plasma immune activation biomarkers neopterin and soluble CD14 (sCD14) in indirect assessment status patients with indeterminate HIV-1 (IHIV-1) pattern a true HIV-1-positive infection (PCG). Methods This cross-sectional descriptive study included eighty-eight IHIV-1 pattern, 100 PCG, people healthy control group (HCG). Neopterin sCD14 levels were determined by competitive sandwich ELISA methods, respectively. Results Mean among those significantly...
Background: Eosinophils may suggest the presence of a great variety anomalies whereupon allergies, malignancies, certain tissue disorders, idiopathic hypereosynophilic syndrome and parasitic infections (with exception protozoons) can be cited as few. Although clinical manifestations differ, eosinophils level is quite an important data in cases related to helminth infections. Similarly, larva migrans (visceral, cutaneous, ocular), again primary indicator its evident cause roundworm Toxocara...
In people living with human immunodeficiency virus (HIV), several complaints related to the gastrointestinal system, mainly diarrhea can be determined. our study, we aimed detect existence of intestinal parasites conventional methods based on microscopy and molecular multiplex-PCR among 90 anti-retroviral treatment (ART) naive or ART adherent HIV/AIDS cases. The Giardia spp., Blastocystis Entamoeba histolytica, Dientamoeba spp. Cryptosporidium were searched in stool samples relation these...
Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium are the three most commonly reported sexually transmitted bacteria. The present study aimed to investigate presence of C. N. M. in urogenital samples collected from 18-68-year-old Turkish patients who were admitted hospital with various symptoms. A total 360 symptoms STD included study. Following DNA extraction by QIAamp Mini Kit, investigated using multiplex real-time PCR. Causative organisms identified 68 (18.9%)...
Viral load varies during infection and is higher the initial stages of disease. Given importance intensive care unit (ICU) in late COVID-19 infection, analyzing cycle threshold values to detect viral upon ICU admission can be a clinically valuable tool for identifying patients with highest mortality risk.This was retrospectively designed study. Patients older than 18 years who tested positive SARS-CoV-2 PCR had PaO2/FiO2 ratio <200 were included The patient population divided into two...
Cytomegalovirus (CMV) can cause serious complications in immunocompromised individuals and fetuses with congenital infections. These include neurodevelopmental impairments abnormalities newborns. This paper emphasizes the importance of concurrently evaluating ultrasonography findings laboratory parameters diagnosing CMV infection. To examine prenatal characteristics DNA-positive patients, we assessed serum amniotic fluid from 141 pregnant women aged 19–45 years, each fetal anomalies. ELISA...
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Respiratory viruses significantly impact public health, contributing to high morbidity and mortality rates in both children adults. This study evaluates the distribution incidence of respiratory tract our hospital from 2019 2022, focusing on changes post-COVID-19 pandemic.
Oral Lichen Planus (OLP) is an immune system disease and its cause has not been fully determined yet. Lichenoid Contact Lesions (OLCL) allergic condition known to develop because of dental materials. It considered that some infectious agents (e.g., Epstein-Barr virus (EBV)) play roles in the etiology OLP OLCL. The purpose present study was investigate presence EBV different clinical samples patients who had OLCL, show relationship with determine role etiopathogenesis these patients.
Hepatitis A infections continue to be a major global public health problem. The epidemiology and seroprevalence of hepatitis virus (HAV) have important implications. This study aimed retrospectively examine the cases in our region hospital with highest number inpatient outpatient Istanbul.