- Antibiotic Resistance in Bacteria
- Asthma and respiratory diseases
- Bacterial Identification and Susceptibility Testing
- Gut microbiota and health
- Antibiotic Use and Resistance
- Virus-based gene therapy research
- Parasitic Infections and Diagnostics
- Vector-borne infectious diseases
- Viral Infections and Immunology Research
- Hepatitis C virus research
- Probiotics and Fermented Foods
- Rabies epidemiology and control
- Antimicrobial Resistance in Staphylococcus
- Helicobacter pylori-related gastroenterology studies
- Pediatric health and respiratory diseases
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Viral gastroenteritis research and epidemiology
- Urinary Tract Infections Management
- Enterobacteriaceae and Cronobacter Research
- Hepatitis Viruses Studies and Epidemiology
- Nuclear Structure and Function
- Bacillus and Francisella bacterial research
- Advanced Biosensing Techniques and Applications
- Biosensors and Analytical Detection
Istanbul Health and Technology University
2024
Gümüşhane University
2018-2023
Linköping University
2020
Istanbul University-Cerrahpaşa
2014-2019
Istanbul University
2014-2018
Geographical variation in the frequency of various gastroduodenal pathologies was shown to be related geographical diversity H. pylori CagA Glu-Pro-Ile-Tyr-Ala (EPIYA) patterns. We examined EPIYA patterns and association with gastric cancer (GC) for first time, best our knowledge, Turkey. The patient group (PG) contained 60 patients [38 GC 22 duodenal ulcer (DU) patients]. control (CG) 110 individuals [94 gastritis 16 persons a normal gastrointestinal system (NGIS)]. Specific primers were...
Hepatitis A virus (HAV) is a food and water-borne causing clinical (mainly hepatitis) subclinical disease in humans. It important to characterize circulating strains of HAV order prevent infections using efficacious vaccines. The aim this study was the detection characterization Turkey by performing serology, RT-PCR, sequencing phylogenetic analysis.In study, 355 suspected cases were analysed ELISA for presence antibodies HAV. RNA extracted from 54 IgM positive human sera. None suspect...
Tick-borne encephalitis virus (TBEV) and West Nile (WNV) are mainly transmitted by arthropod vectors to vertebrate hosts including humans, resulting in fever neurological signs. The aim of this study was investigate the presence antibodies TBEV WNV, TBEV-RNA WNV-RNA Turkish children with and/or arthritis. For purpose, 110 sera buffy-coat samples were collected; analyzed indirect enzyme-linked immunosorbent assay for IgM IgG buffy-coat-derived white blood cells quantitative real-time RT-PCR...
Vancomycin-resistant enterococci (VRE) are a serious problem all over the world. The present study was conducted to investigate antimicrobial resistance patterns, genotypes, clonal relationship, and virulence fac- tors of VRE species isolated from rectal swab samples hospitalized patients, patient's relatives, medical staff at Istanbul University Cerrahpasa Medical School hospital.The isolates were typed with an automated VITEK system their antibiotic sensibilities analysed by disc diffusion...
Neopterin and soluble CD14 (sCD14) are detected at high levels in hepatitis C virus (HCV) infections.We aimed to evaluate the role of these plasma immune activation biomarkers, for indirect assessment status patients with low anti-HCV reactivity a HCV infection.Low group (LRG, n: 70), true positive infection (THG, 30) healthy control (HCG, were analyzed this study.We have used ELISA, RIBA/LIA HCV-RNA methods.Mean neopterin significantly lower LRG than THG (p <0.001).In contrast, those values...
Hepatitis A and E viruses (HAV HEV) are recognised as food- water-borne infections shellfish a well-documented source of these viruses. The presence HAV HEV in mussels has not previously been investigated Bosphorus, Istanbul, Turkey, therefore the aim this study was to investigate frequency collected from location. total 92 pooled samples representing 736 originating along Bosphorus coast were fish distributors. RNA extracted using RNeasy Plant Mini Kit TaqMan real-time RT-PCR performed...
Background: Aerobic and especially anaerobic bacteria of the skin flora victim oral biter were reported as playing an important role in ethiology bite infection which can lead to serious complication.The aim this study is determine aerobic pus samples wound abscesses detect antimicrobial resistances bacteria. Methods & Materials: From December 2012 until November 2013, taken from 53 young adult patient's abscess (12 human bites, 41 animal bites) studied. isolated using standard...
Background: It was reported that there is an inverse relationship between the presence of H.pylori and asthma Th2 response may be directed to Th1 in asthmatic persons by HP-NAP A. We reporte quantity gut microbiota children with allergic comparing healthy controls. Additionnaly we report gene expression levels Methods & Materials: From March 2014 January 2015 bacterial DNA RNA were isolated from stool samples 92 aged 3 8 years 88 age, gender matched The determined Real Time PCR cDNA...
Background: Dientamoeba fragilis is a neglected intestinal protist associated with clinical outcomes in humans. There still an obscurity about its pathogenicity humans, including whether it can modulate immune responses, through which mechanisms initiates infection, or mostly silent resident of human gut. are many studies and case reports all indicate D. as the causative agent patients diarhhea, abdominal pain, meteorism urticaria. Yet, may have pathogenic subtypes and/or act pathogen under...
Background: Neopterin and sCD14 levels could be detected at high in HBV, HCV HIV infections as well pathologies including trauma, sepsis rheumaoid arthritist. We aimed to evaluate the importance of neopterin for determination infection situations where low Anti-HCV reactivity indeterminate RIBA are present. also compose a new diagnostic perspective atypical cases which have different results Methods & Materials: As Total Study Group (TSG), 70 individuals with reactive test due > 1-<3,8...