Yeşim Tok

ORCID: 0000-0003-4970-9216
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 detection and testing
  • Animal Virus Infections Studies
  • Vaccine Coverage and Hesitancy
  • Hepatitis B Virus Studies
  • Medical and Biological Ozone Research
  • Biosensors and Analytical Detection
  • Laser Applications in Dentistry and Medicine
  • Occupational health in dentistry
  • Viral gastroenteritis research and epidemiology
  • Respiratory viral infections research
  • Retinal and Optic Conditions
  • Hepatitis C virus research
  • Long-Term Effects of COVID-19
  • Ocular Diseases and Behçet’s Syndrome
  • Turkish Literature and Culture
  • Bacillus and Francisella bacterial research
  • Immunotherapy and Immune Responses
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Probiotics and Fermented Foods
  • Garlic and Onion Studies
  • Infection Control and Ventilation
  • Infections and bacterial resistance
  • Viral Infections and Immunology Research

Istanbul University-Cerrahpaşa
2021-2024

Izmir Kâtip Çelebi University
2018-2024

Istanbul University
2022

It is essential to know about immune response levels after booster doses of the two different types vaccines, mRNA, and inactivated, currently used against COVID-19. For this purpose, we aimed determine effects BNT162b2 (BNT) CoronaVac (CV) boosters on humoral cellular immunity individuals who had CV vaccination.

10.1111/all.15316 article EN Allergy 2022-04-19

This study aimed to evaluate the performance characteristics of a rapid antigen test developed detect SARS-CoV-2 (COVID-19), influenza A virus (IAV), and B (IBV) (flu) compared with those real-time reverse transcription-polymerase chain reaction (rRT-PCR) method. One hundred SARS-CoV-2, one IAV, twenty-four IBV patients whose diagnoses were confirmed by clinical laboratory methods included in patient group. Seventy-six patients, who negative for all respiratory tract viruses, as control The...

10.3390/diagnostics13050972 article EN cc-by Diagnostics 2023-03-03

Abstract Myroides spp. are opportunistic environmental Gram-negative bacteria. These affect mostly immunocompromised hosts and generally lead to soft tissue, urinary tract infections. Bacteremia most commonly develop secondary tissue or catheter related infections may rarely mortality. suscetible fluoroquinolones, piperacillin/tazobactam, trimethoprim/sulfamethoxazole, carbapenems tetracyclines however, pan-resistant isolates multiple resistance genes have been reported in clinical of We...

10.1556/030.2022.01702 article EN Acta Microbiologica et Immunologica Hungarica 2022-03-21

Numerous vaccines have been generated to decrease the morbidity and mortality of COVID-19. This study aims evaluate immunogenicity heterologous boosts by BioNTech against homologous CoronaVac at three-month intervals in two health care worker (HCW) cohorts, with or without prior COVID-19, for one year post-vaccination. is a prospective cohort which humoral responses 386 HCWs were followed-up longitudinally six main groups according their previous COVID-19 exposure vaccination status....

10.3390/vaccines11020355 article EN cc-by Vaccines 2023-02-03

Monitoring the longevity of immunoglobulin G (IgG) responses following severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections is vital to understanding role antibodies in preventing infection.To determine quantitative IgG specific Spike-S1 (S1) receptor-binding domain (S1/RBD) region virus serum samples taken between 4 weeks and 7 months after polymerase chain reaction (PCR) positivity patients who are diagnosed with coronavirus disease-2019 (COVID-19).A longitudinal...

10.4274/balkanmedj.galenos.2022.2021-8-131 article EN cc-by-nc-nd Balkan Medical Journal 2022-04-05

COVID-19 vaccines are highly protective against severe disease; however, vaccine breakthrough infections resulting in hospitalization may still occur a small percentage of vaccinated individuals. We investigated whether the clinical and microbiological features outcomes were different between hospitalized patients who either fully with Coronovac or not. All had at least one dose Coronavac included study. The oldest unvaccinated comorbidities, during same period, chosen as controls....

10.3390/vaccines10050733 article EN cc-by Vaccines 2022-05-07

SARS-CoV-2 ile İlgili Farklı Prensipli Ticari Antikor Testlerinin COVID-19 Hastalarındaki Tanısal Performanslarının Değerlendirilmesi However, it is thought that the combined use of both ECLIA/CLIA-based and EIA/ELISA-based tests together may be more effective in routine for IgG tests.

10.5578/mb.20219907 article EN Mikrobiyoloji Bulteni 2021-04-19

The gold standard in the definitive diagnosis of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is nucleic acid amplification tests (NAAT) due to their high sensitivity and specificity detecting viral ribonucleic acid. However, while leaving two years behind pandemic, resources have come point exhaustion terms both economy manpower working field health services. Therefore, need for rapid, simple accurate diagnose SARS-CoV-2 infection continues. In this study, it was aimed...

10.5578/mb.20229805 article EN Mikrobiyoloji Bulteni 2022-04-25

As viruses spread through a population, they mutate and change, leading to the evolution of slightly different forms or variants. SARS-CoV-2 has been mutating ever since it was first detected in Wuhan, China, December 2019. While most mutations will not have significant effect on virus, some (...)

10.36519/idcm.2021.43 article EN cc-by-nc Infectious Diseases and Clinical Microbiology 2021-08-31

Background: Widespread and effective use of molecular diagnostic tests is indispensable for protecting public health containing the severe respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.More than 1 year into pandemic, as resources have reached a point depletion, grouping samples in pools certain sizes appears to be reasonable method reduce both costs processing time without necessitating additional training, equipment, or materials. Aims:To assess whether pooling strategy that was...

10.5152/balkanmedj.2021.21135 article EN cc-by-nc-nd Balkan Medical Journal 2021-12-03

Objective: In Turkey, the fourth wave of SARS-CoV-2 started in December 2021 and peaked mid-January 2022. Afterward, peaks were seen number COVID-19 cases because Omicron BA.2 BA.5 variants. Our study aimed to observe prevalence viral load-related transmissibility rates variant infections our region between January 21 July 01, 2022, using an easy cost-effective PCR screening method.

10.36519/idcm.2022.143 article EN cc-by-nc Infectious Diseases and Clinical Microbiology 2022-09-26

da, Çin'in Wuhan şehrinde ilk tespitinden bu yana, koronavirüs hastalığı-2019 (COVID-19) bir pandemiye dönüşerek dünya çapında yüksek oranda ölüm ve ekonomik kayıplara neden olmuştur.Şiddetli akut solunum sendromu koronavirüs-2 (SARS-CoV-2) zoonotik, pozitif polariteli RNA virüsü olup, viral enfeksiyon replikasyonda rol oynayan proteinleri hedef alan nötralizan antikorların üretimini de kapsayan immün yanıt başlatır ki oluşan antikorlar aylarca plazmada saptanır düzeyde kalır, virüs...

10.5578/mb.20219704 article TR Mikrobiyoloji Bulteni 2021-10-18

Amaç: Bu çalışmanın amacı, laboratuvarımızda son 5 yılda gastroenterit ön tanısı almış hastalardan alınan örneklerde viral etken profilini değerlendirmektir.Gereç ve Yöntem: çalışmada,

10.17932/iau.tfk.2018.008/tfk_v06i2003 article TR AYDIN TIP FAKÜLTESİ KLİNİKLERİ DERGİSİ 2018-01-01

Hepatitis B infection is still among the most important public health problems worldwide, even great improvements have been made in treatment strategies. virus (HBV) replicates itself by entering liver cells and simultaneously with antigen release, many antagonistic immune responses are induced regulatory including T cell (Treg), helper 17 (Th17), 1 (Th1) 2 (Th2) cells. The main function of Treg to develop an appropriate response against suppress if it not required. Tregs effector via...

10.5578/mb.69340 article EN Mikrobiyoloji Bulteni 2020-04-15

Hepatitis C virus (HCV), defined as a non-A non-B hepatitis agent in 1989, is hepatotropic, noncytopathic, positive-stranded ribonucleic acid (RNA) from the family Flaviviridae. HCV infection an acute or chronic necroinflammatory (...)

10.36519/idcm.2021.68 article EN cc-by-nc Infectious Diseases and Clinical Microbiology 2021-12-30
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