Mesut Akıl

ORCID: 0000-0002-0147-1731
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Research Areas
  • Parasitic infections in humans and animals
  • Congenital Anomalies and Fetal Surgery
  • Parasitic Infections and Diagnostics
  • Parasite Biology and Host Interactions
  • Amoebic Infections and Treatments
  • Viral gastroenteritis research and epidemiology
  • Gut microbiota and health
  • Helminth infection and control
  • Inflammatory Bowel Disease
  • Vibrio bacteria research studies
  • vaccines and immunoinformatics approaches
  • Monoclonal and Polyclonal Antibodies Research
  • Helicobacter pylori-related gastroenterology studies
  • Parasites and Host Interactions
  • Legionella and Acanthamoeba research
  • Biosensors and Analytical Detection
  • Coccidia and coccidiosis research

Istanbul Medeniyet University
2020-2023

Ege University
2020-2022

Amaç: Serbest yaşayan amiplerden biri olan Acanthamoeba, başta su, toprak ve hava olmak üzere birçok çevresel örnekte tespit edilmiştir.Acanthamoeba'nın neden olduğu en önemli klinik tablolar içinde Acanthamoeba keratiti granülomatöz amibik ensefalit bulunmaktadır.Bu çalışmada örneklerde Acanthamoeba'nın varlığının daha hızlı bir şekilde saptanabilmesi için 18S rRNA gen bölgesine özgü primerler ile geliştirilen döngü aracılı izotermal amplifikasyon (LAMP) testinin hassasiyetinin belirlenmesi...

10.4274/tpd.galenos.2023.46362 article TR cc-by-nc-nd Turkish Journal of Parasitology 2023-09-18

Fasciola hepatica is an important pathogen that causes liver fluke disease in definitive hosts such as livestock animals and humans. Various excretory/secretory products have been used serological diagnosis vaccination studies targeting fasciolosis. There are no commercial vaccines against fasciolosis yet. Bioinformatic analysis based on computational methods lower cost provide faster output compared to conventional vaccine antigen discovery techniques. The aim of this study was predict B-...

10.1080/14760584.2022.1996233 article EN Expert Review of Vaccines 2021-10-21

Summary In Turkey, cyst hydatid disease (CHD) or cystic echinococcosis (CE) is publicly known as “dog cyst”, a fatal and serious not only affects livestock husbandry human health but also brings about economic loss to our country. According the data of Ministry Health; number annual cases was 408 in 2008, this reached 1,867 by end 2019. Cystic especially taken up during childhood emerged at an older age. They become exposed eggs tapeworm after close contact with infected dog its contaminated...

10.2478/helm-2021-0013 article EN cc-by-nc-nd Helminthologia 2021-06-01

Objective: Blastocystis is a common protozoan parasite detected worldwide. This study aims to investigate the in vitro inhibitory effect of ethyl alcohol extracts Tunceli garlic (Allium tuncelianum) on growth ST3 subtype.Methods: were grown 3 ml Jones's medium containing A. tuncelianum prepared at five different concentrations for 72 hours 37°C. Distilled water was used as negative control whereas metronidazole (MTZ) and trimethoprim-sulfamethoxazole (TMP-SMX) 0.1, 0.5 1 mg/ml positive...

10.1080/21678707.2020.1857725 article EN Expert Opinion on Orphan Drugs 2020-11-01

Objective: To date, many studies have been performed on genotyping of E. granulosus s.l. in Turkey. However, a systematically analysis the data human genotypes Turkey is lacking. In this context, aim study to provide summary information about distribution E.granulosus which detected with molecular methods isolates Materials and Methods: Both English Turkish four international national databases up September 2022 were searched keywords related “Echinococcus” access eligible articles for our...

10.5455/ije.2023.01.01 article EN International Journal of Echinococcoses 2023-01-01

Kistik ekinokokkozis (KE), Avrupa'da çok yaygın bir hastalıktır ve dünyada yaklaşık 2-3 milyon olgunun % 95'inden fazlasını oluşturmaktadır. KE, ölümcül ciddi hastalıktır. Türkiye de bu sorunun halen halk sağlığı tehdidi oluşturduğu ülkeler arasındadır. Bu çalışma, İzmir ilinin 10 farklı ilçesinde KE farkındalığını yaratmak için yapılmış pilot çalışmadır. Farkındalık artırma seminerleri, öğrenciler okul öğretmenleri çalışmanın temel bileşenidir. Ayrıca anket formları oluşturularak sunum...

10.51754/cusbed.880941 article TR Cumhuriyet Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 2021-03-30

Objective: The aim of the study is to determine prevalence Echinococcus granulosus sensu lato by molecular analysis with Real Time PCR (RT-PCR) method collecting stool samples from stray animals that can be reached in 9 10 determined districts Izmir province (Aliaga, Menemen, Bornova, Urla, Selcuk, Bayindir, Odemis, Tire, Kiraz). Materials and Methods: Thirty Aliaga, 41 35 40 Bayındır, 33 45 26 Kiraz, totally 300 were collected. left at −80°C for 5 days inactivate. Afterwards, all...

10.5455/ije.2022.09.012 article EN International Journal of Echinococcoses 2022-01-01

The aim of this study was to investigate whether Enzyme-Linked Immunosorbent Assays (ELISA) and Western Blotting (WB) methods could contribute the assessment clinical outcomes in genotype-defined cystic echinococcosis (CE) patients. Twenty-nine human isolates blood samples have been taken from patients who underwent surgery or percutaneous aspiration (PAIR) for therapeutic purposes at Ege University Manisa Celal Bayar Hospitals. All sera were screened presence E. granulosus IgG antibodies...

10.2478/helm-2020-0012 article EN cc-by-nc-nd Helminthologia 2020-05-23

Objective: Cystic echinococcosis (CE) caused by larval stage of Echinococcus granulosus is one the neglected parasitic disease, both medical and public health importance. It has a worldwide distribution including Turkey. The current study was designed to determine seropositivity E. infection in patients with suspected cystic attending Dr.Ersin Arslan Training Research Hospital Gaziantep, Materials Methods: A total 545 serum samples were taken from individuals screened for presence IgG...

10.5455/ije.2021.07.05 article EN International Journal of Echinococcoses 2022-01-01

Objective: To evaluate three different serological tests [Indirect Hemaglutination (IHA), Enzyme Linked Immunosorbent Assay (ELISA) and Western Blotting (WB)] using native crude antigen for diagnosis of hepatic cystic echinococcosis (HCE) patients. Materials Methods: Sheep hydatid fluid (HF) was collected from fertile cysts obtained a slaughterhouse used as an antigen. Forty patients who were attended the Dr. Ersin Arslan Training Research Hospital in Gaziantep, Turkey, investigated. Serum...

10.4236/ojmm.2021.112006 article EN Open Journal of Medical Microbiology 2021-01-01

Comparison of the New Multiepitope Recombinant Peptide Antigen with Cyst Fluid in Follow-up Patients Cystic EchinococcosisAmaç: Çalışmada, kistik ekinokokkozisli (KE) hastaların takibi, enfeksiyonun prognozu ve tekrarlayan kistlerin mümkün olan en kısa sürede tespiti konularında değerlendirme imkanı sunulmaktadır.Ayrıca, yeni multiepitop rekombinant peptit (recDipol) antijeninin cerrahi veya perkütan aspirasyon enjeksiyon reaspirasyon işlemi uygulanan KE'li takibindeki performansının...

10.4274/tpd.galenos.2021.7286 article TR cc-by-nc-nd Turkish Journal of Parasitology 2021-08-04
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