A5013039320- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Lung Cancer Research Studies
- Adrenal and Paraganglionic Tumors
- Cancer, Hypoxia, and Metabolism
- Adrenal Hormones and Disorders
- Pituitary Gland Disorders and Treatments
- Immunodeficiency and Autoimmune Disorders
- Pancreatic and Hepatic Oncology Research
- Apelin-related biomedical research
- Vitamin D Research Studies
- Inflammation biomarkers and pathways
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research
- Renal Transplantation Outcomes and Treatments
- Ion Channels and Receptors
- IgG4-Related and Inflammatory Diseases
- Pancreatitis Pathology and Treatment
- Alkaline Phosphatase Research Studies
- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- Bone health and treatments
Ankara University
2024-2025
Hacettepe University
2020-2024
<title>Abstract</title> Idiopathic Infantile Hypercalcemia (IIH) is a rare disorder marked by PTH-independent hypercalcemia, usually diagnosed in infancy, with adult cases being uncommon. This report discusses 60-year-old male 25-year history of type 2 diabetes, recurrent kidney stones, and stage 3a chronic disease. Laboratory findings included normal phosphorus 25-hydroxycholecalciferol levels, suppressed PTH. Urinary ultrasonography revealed medullary nephrocalcinosis. Comprehensive...
Abstract Background Grade 1/2 PanNETs are mostly managed similarly, typically without any adjunct treatment with the belief that their overall metastasis rate is low. In oncology literature, Ki67-index of 10% increasingly being used as cutoff in stratifying patients to different protocols, although there no systematic pathology-based studies supporting this approach. Methods was correlated clinicopathologic parameters 190 resected PanNETs. A validation cohort ( n = 145) separately analyzed....
Abstract Background Intriguingly, liver regeneration after injury does not induce uncontrolled growth and the underlying mechanisms of such a “ hepatostat ” are still clear. Endocan, proteoglycan, was implicated in regeneration. It can support function hepatocyte factor/scatter factor tissue repair injury. Endostatin, 20 kDa C-terminal fragment collagen XVIII, may modulate cessation eEF2K, protein kinase that regulates synthesis, regulate angiogenesis. Thus, we investigated role endocan,...
Loss of function mutations in Diaphanous related formin 1 (DIAPH1) are associated with seizures, cortical blindness, and microcephaly syndrome (SCBMS) recently linked to combined immunodeficiency. However, the extent defects T innate lymphoid cells (ILCs) remain unexplored. Herein, we characterized primary T, natural killer (NK) helper ILCs six patients carrying two novel loss mutation DIAPH1 Jurkat after knockdown. Mutations were identified by whole exome sequencing. T-cell...
Olmsted syndrome is a rare congenital keratinization disorder characterized by mutilating palmoplantar keratoderma, often accompanied flexion deformity, periorificial keratotic plaques and hair abnormalities. The majority of cases are attributed to mutations in TRPV3. We report patient with sporadic case recurrent c.1717G&gt;T p.Gly573Cys variant TRPV3, who demonstrated clinical improvement when treated the epidermal growth factor inhibitor erlotinib.
Abstract Introduction Prader-Willi syndrome (PWS) is the leading inherited cause of severe childhood obesity. The aim this case report to describe a delayed diagnosis PWS and emphasize importance early PWS. Clinical Case A 24-year-old young woman with history hyperphagia, obesity, cognitive impairment was admitted our department for glycemic control due newly diagnosed type 2 diabetes mellitus. She also had obstructive sleep apnea, daytime sleepiness, scoliosis, short stature (148 cm),...
Everolimus-associated cytomegalovirus colitis is very rare in cancer patients. We present a case of that occurred on using everolimus 64-year-old male with metastatic renal cell carcinoma who received pazopanib, nivolumab, and treatments, respectively. Although an increasing number nivolumab-related cases are reported recently, its mechanism development still unknown. Our study highlights clinicians should remember reactivation the presence diarrhea or patients receiving and/or nivolumab....