A5028601350- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Colorectal Cancer Surgical Treatments
- Diverticular Disease and Complications
- Gastrointestinal motility and disorders
- Colorectal and Anal Carcinomas
- Urinary Bladder and Prostate Research
- Hernia repair and management
- Music Therapy and Health
- Congenital gastrointestinal and neural anomalies
- Acupuncture Treatment Research Studies
- Effects of Radiation Exposure
- Inflammatory Bowel Disease
- Cardiac, Anesthesia and Surgical Outcomes
- Myofascial pain diagnosis and treatment
- Advanced Radiotherapy Techniques
- Appendicitis Diagnosis and Management
- Prostate Cancer Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Management of metastatic bone disease
- Elasticity and Material Modeling
- Airway Management and Intubation Techniques
- Lymphatic System and Diseases
- Therapeutic Uses of Natural Elements
- Diagnosis and treatment of tuberculosis
Aarhus University Hospital
2015-2025
Danish Cancer Society
2018-2021
Aarhus University
2019
State Scientific Center of Coloproctology
2018
Massachusetts General Hospital
2018
Pontificia Universidad Católica de Chile
2018
Aalborg University
2018
National Research University Higher School of Economics
2018
Maastricht University Medical Centre
2018
Hôpital de la Timone
2018
Adjuvant radiotherapy in the treatment of rectal cancer has been shown to increase long-term morbidity causing severe anorectal dysfunction with physiologic changes whose interaction remains poorly understood. This study examines from adjuvant postoperative radiotherapy.In a prospective study, patients Dukes B or C carcinoma were randomized no after anterior resection. The effect on function subset surviving was assessed questionnaire subjective symptoms and physiology laboratory evaluation...
PURPOSE: Sacral nerve stimulation is one of many new surgical modalities for fecal incontinence. Short-term results from sacral have been more encouraging than those other modalities. The aim this study was to report the outcome percutaneous evaluation tests and treatment incontinence a single center covering period 6 years since procedure introduced. METHODS: All candidates test seen at our anal physiology unit between March 2001 2007 were included in study. RESULTS: A total 177 patients...
This study aimed to evaluate the outcome of sacral nerve stimulation (SNS) for fecal incontinence at 5 years after implantation and identify predictors sustained efficacy.There is a lack knowledge about long-term SNS incontinence.Prospectively collected data from patients who underwent an device between 2001 2006 were reviewed.One hundred one available evaluation years. Sixty 101 [42.6% on intention-to-treat (ITT) 55.6% per protocol (PP)] reported favorable outcome, 41 (ITT 29.1%; PP 38.0%)...
<h3>Background and Objectives</h3> Ultrasound-guided techniques for pudendal nerve block have been described at the level of ischial spine transperineally. Theoretically, however, blockade inside Alcock canal with a small local anesthetic volume would minimize risk sacral plexus anesthetize all 3 branches before they ramify in ischioanal fossa. This technical report describes new ultrasound-guided technique to nerve. The indicates an easy effective roadmap target by following margin hip bone...
Phantom breast syndrome after mastectomy has already been reported by us and other authors. The temporal course, character, extent of these phenomena, however, have not yet elucidated. Objective To investigate in a prospective study the incidence, clinical picture, course phantom during 6-year period. Design One-hundred twenty women who embarked on consecutive postoperative control or treatment at our department 1-year period were interviewed standard questionnaire 3 weeks operation. Of...
The treatment of complex anorectal and rectovaginal fistulae remains a difficult problem. options are fistulotomy, setons, fibrin glue variety flap procedures. Recently, there have been several reports new plug; the Surgisis AFP plug. Reports from various centres do not give consistent results. aim this study was to assess efficacy fistula plug in wide spectrum patients with anorectal, pouch vaginal fistulae.Between March 2006 September 2007, anal were selected for insertion coloproctology...
Abstract Background The aim of the study was to identify incidence suboptimal therapeutic responses and adverse events associated with sacral nerve stimulation (SNS) for faecal incontinence, determine their influence on treatment outcome. Methods Prospectively collected data from 176 patients who underwent SNS were reviewed retrospectively. Patient variables reportable analysed by binary regression predictors Results Overall, 592 recorded 150 (85·2 per cent) at a median 11 (interquartile...
OBJECTIVE: This study aimed to test the hypothesis that sacral nerve stimulation affects afferent vagal projections central nervous system associated with frontal cortex activation in patients fecal incontinence. PATIENTS: Nine women and one man received temporary permanent electrodes as a treatment for INTERVENTIONS: We used positron emission tomography record indices of regional cerebral blood flow before after 30 minutes continuous stimulation. repeated this procedure 2 weeks continued...
Abstract Aim The objective of primary radiotherapy for anal cancer is to remove while maintaining anorectal function. However, little known about function among long‐term survivors without colostomy. Using a cross‐sectional questionnaire study, we examined symptoms and distress related the dysfunction pelvic organs after cancer. Method A regarding anorectal, urinary sexual was sent patients recurrence or colostomy, diagnosed during 1996–2003, treated with curative intent (chemo)radiotherapy...
A variety of therapeutic approaches are available for faecal incontinence. Implantation Gatekeeper prostheses is a new promising option. The primary endpoint this prospective observational multicentre study was to assess the clinical efficacy implantation in patients with Secondary endpoints included assessment patients' quality life, and feasibility safety implantation.Patients incontinence, either intact sphincters or internal anal sphincter lesions extending less than 60° circumference,...
Laparoscopic ventral mesh rectopexy (LVMR) for rectal prolapse has been implemented to reduce postoperative bowel symptoms. The preoperative-to-postoperative change in a double-blinded, randomized study comparing it laparoscopic posterior sutured (LPSR) found no significant difference between the two procedures after one year. aim of this was investigate long-term functional outcomes.From November 2006-January 2014, 75 patients were LVMR (n = 37) or LPSR 38). In March 2017, questionnaires...
Abstract Aim Sacral neuromodulation (SNM) is approved for the treatment of faecal incontinence (FI) in a two‐stage technique. With standardized implantation, approximately 90% patients undergo successful Stage I operation and proceed to permanent implant (Stage II). The aim this work was explore feasibility SNM as one‐stage procedure report 24‐week efficacy. Method This study included diagnosed with idiopathic FI or due an external anal sphincter defect ≤160° one more episodes per week...
PURPOSE: Sacral nerve stimulation is an emerging treatment for patients with severe constipation. There has been no substantial report to date on suboptimal outcomes and complications. We our experience of more than 6 years by focusing incidents the management reportable events. METHODS: A retrospective review was performed who underwent sacral constipation between August 2002 September 2008. Collected data included patients' demographic data, type complications, parameters at time RESULTS:...
Abstract Background Anatomical structures and their distensibility vary along the length of anal canal. The sphincter muscles have dynamic properties that are not well‐reflected by standard manometry. Abnormal canal may be importance in idiopathic fecal incontinence ( IFI ). functional lumen imaging probe FLIP ) allows detailed studies axial variation sphincters. We aimed at comparing segmental patients with healthy subjects. Methods was used for distension 22 (17 female, age 27–82 years) 21...
Sacral nerve stimulation (SNS) is an established treatment for faecal incontinence (FI) when conservative modalities have failed to restore continence. This two-centre study aimed document functional outcome and its relationship patient satisfaction.Patients treated with SNS idiopathic FI in Aarhus (Denmark) Maastricht (The Netherlands) were included. At the most recent follow-up appointment, 127 patients (80%) identified as receiving active therapy. A questionnaire considering bowel habits,...
In Brief Objective: To investigate whether sacral nerve stimulation reduces irritable bowel syndrome (IBS)-specific symptoms by a randomized, controlled, crossover study. Background: IBS affects 3% to 22% of the population worldwide, but most patients continue have despite treatment. Methods: Patients included from our tertiary center had diarrhea-predominant or mixed IBS, with minimum baseline symptom score (Gastrointestinal Syndrome Rating Scale–IBS questionnaire) 40 points reduced 30%...
Clinical decision-making in the treatment of patients with obstructed defaecation remains controversial and no international guidelines have been provided so far. This study reports a consensus among European opinion leaders on management different possible clinical scenarios.