Arcangelo Picciariello
A5071669564- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Surgical Treatments
- Pelvic floor disorders treatments
- Diverticular Disease and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Appendicitis Diagnosis and Management
- Gastric Cancer Management and Outcomes
- Advanced Chemical Sensor Technologies
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Pelvic and Acetabular Injuries
- Abdominal Surgery and Complications
- Olfactory and Sensory Function Studies
- Bariatric Surgery and Outcomes
- Global Health and Surgery
- Hernia repair and management
- Diversity and Career in Medicine
- Surgical Simulation and Training
- Analytical Chemistry and Chromatography
- Minimally Invasive Surgical Techniques
- Esophageal and GI Pathology
- Trauma and Emergency Care Studies
- Gastrointestinal Tumor Research and Treatment
- Enhanced Recovery After Surgery
University of Salento
2023-2025
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2018-2024
University of Bari Aldo Moro
2016-2023
Collaborative Group (United States)
2021-2023
Kyungpook National University Hospital
2023
University of Göttingen
2022
University of Birmingham
2022
National Institute for Health Research
2022
Istituti di Ricovero e Cura a Carattere Scientifico
2021
Istituto Tumori Bari
2021
Abstract Background Effective screening for colorectal cancer can reduce mortality by early detection of tumours and colonic polyps. An altered pattern volatile organic compounds (VOCs) in exhaled breath has been proposed as a potential non-invasive diagnostic tool cancer. The aim this study was to evaluate the reliability breath-testing diagnosis using an advanced sampler. Methods patients with non-cancer controls negative findings on colonoscopy collected ReCIVA® Breath Sampler. This...
Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed describe international variation in drain placement and the safety this practice.COMPASS (COMPlicAted intra-abdominal collectionS Surgery) was prospective, international, cohort which enrolled consecutive adults undergoing (February March 2020). The primary outcome...
Abstract Background The spread of the SARS-CoV2 virus, which causes COVID-19 disease, profoundly impacted surgical community. Recommendations have been published to manage patients needing surgery during pandemic. This survey, under aegis Italian Society Endoscopic Surgery, aims analyze how surgeons changed their practice Methods authors designed an online survey that was circulated for completion departments general registered in Ministry Health database December 2020. Questions were...
We recently reported that activation of Trop-2 through its cleavage at R87-T88 by ADAM10 underlies Trop-2–driven progression colon cancer. However, the mechanism action and pathological impact in metastatic diffusion remain unexplored. Through searches for molecular determinants cancer metastasis, we identified TROP2 as unique up-regulation across independent metastasis models. Overexpression wild-type KM12SM human cells increased liver rates vivo immunosuppressed mice. Metastatic growth was...
Clinical decision-making in the treatment of patients with obstructed defaecation remains controversial and no international guidelines have been provided so far. This study reports a consensus among European opinion leaders on management different possible clinical scenarios.
The COVID-19 pandemic is having a deep impact on emergency surgical services, with significant reduction of patients admitted into units world widely. Reliable figures this have not been produced yet. Our international audit aimed at giving precise snapshot the absolute and relative changes admissions outbreak pandemic.Datasets as general emergencies 45 internationally distributed during months March April 2020 (Covid-19 outbreak) were collected compared those same 2019 (pre-Covid-19)....
Bariatric surgery is a safe and effective treatment for obesity, although in super-obese patients (BMI ≥50 kg/m2) it can become challenging anatomical anesthesiologic issues. Several bridging therapies have been proposed to increase preoperative weight loss decrease perioperative morbidity mortality. The aim of this study was compare the efficacy safety different two-stage approaches patients: laparoscopic sleeve gastrectomy (LSG) following liraglutide therapy versus LSG with intragastric...
Screening methods available for colorectal cancer (CRC) to date are burdened by poor reliability and low patient adherence compliance. An altered pattern of volatile organic compounds (VOCs) in exhaled breath has been proposed as a non-invasive potential diagnostic tool distinguishing CRC patients from healthy controls (HC). The aim this study was evaluate the an innovative portable device containing micro-gas chromatograph enabling rapid, on-site diagnosis through analysis patients’ breath....
Abstract TROP2 was previously shown to drive metastatic diffusion of colorectal cancer (CRC), upon proteolytic activation by ADAM10. Trop-2 lead cleavage E-cadherin, with release from the scaffolding cytoskeleton and disruption cell-cell junctions. This suggested that Trop-2-driven loss cell adhesion is pivotal for acquisition invasion capacity in CRC. Tumor budding play a role CRC at tumor/stroma interface impact on disease outcome. We thus investigated whether associated budding. Our...
Percutaneous tibial nerve stimulation (PTNS) is a minimally invasive procedure which has been demonstrated to be effective in faecal/urinary incontinence but never tested low anterior resection syndrome (LARS). The severity of LARS may evaluated by the score, rectal cancer treatments also affect urinary and sexual function, are not explored score. Three Axial Perineal Evaluation (TAPE) score new validated index addressing overall pelvic floor functions. This study aims assess efficacy PTNS...
Abstract Aim The management of haemorrhoids has changed significantly in the last two decades as a result new insights into their pathophysiology and availability surgical devices. aim this survey was to evaluate changes Italy over 17 years. Method An electronic database which recorded details relating severity between 2000 2016 obtained from 18 34 colorectal surgeons who were invited participate. Results A total 32 458 patients treated for by expert coloproctologists during 17‐year period....
Sclerotherapy with 3% polidocanol foam is becoming increasingly popular for the treatment of symptomatic I-II or III degree haemorrhoidal disease (HD). However, there are no studies that have reported a follow-up more than 1 year. The purpose this study was to analyse long-term outcomes sclerotherapy in II-degree HD.This an open label, single-arm, phase 2b trial conducted 10 tertiary referral centres HD. A total 183 patients HD, aged between 18 and 75 years HD according Goligher...
Chronic kidney disease (CKD) may result in end-stage renal disorder and an increased mortality rate. Presently, transplantation represents the only definitive treatment to restore normal life expectancy. Nevertheless, there is elevated risk of organ rejection short–medium term after surgery. This preclinic study proposes optimization innovative, fast, non-invasive, cheap thermal desorption-gas chromatograph–mass spectrometry (TD-GC–MS) protocol, which provides simple monitoring respiratory...