André L. Mihaljević
- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Hernia repair and management
- Gallbladder and Bile Duct Disorders
- Neuroendocrine Tumor Research Advances
- Esophageal and GI Pathology
- Renal cell carcinoma treatment
- Esophageal Cancer Research and Treatment
- Surgical site infection prevention
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Clinical practice guidelines implementation
- Interprofessional Education and Collaboration
- Innovations in Medical Education
- Enhanced Recovery After Surgery
- Stoma care and complications
- Health and Medical Research Impacts
- Intraperitoneal and Appendiceal Malignancies
- Medical Practices and Rehabilitation
- Appendicitis Diagnosis and Management
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Screening and Detection
- Palliative Care and End-of-Life Issues
Technical University of Munich
2008-2025
University Children's Hospital Tübingen
2023-2025
Klinikum rechts der Isar
2008-2025
Universitätsklinikum Tübingen
2023-2025
München Klinik
2025
University Hospital Ulm
2021-2024
Heidelberg University
2015-2024
University Hospital Heidelberg
2015-2024
Yahoo (United Kingdom)
2024
Universität Ulm
2023
Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global priority not fully understood. We quantified burden SSI after gastrointestinal surgery in countries all parts world.
Objectives: To assess pancreatic fistula rate and secondary endpoints after pancreatogastrostomy (PG) versus pancreatojejunostomy (PJ) for reconstruction in pancreatoduodenectomy the setting of a multicenter randomized controlled trial. Background: PJ PG are established methods pancreatoduodenectomy. Recent prospective trials suggest superiority regarding perioperative complications. Methods: A trial comparing with was conducted involving 14 German high-volume academic centers surgery. The...
Open partial pancreatoduodenectomy (OPD) represents the current gold standard of surgical treatment a wide range diseases pancreatic head but is associated with morbidity in around 40% cases. Robotic (RPD) being used increasingly, yet, no randomised controlled trials (RCTs) RPD versus OPD have been published, leaving low level evidence to support this practice. This investigator-initiated, exploratory RCT two parallel study arms was conducted at high-volume centre line IDEAL recommendations...
To evaluate the impact of clinical and pathological parameters, including resection margin (R) status, on survival in patients undergoing pancreatic surgery after neoadjuvant treatment for initially unresectable ductal adenocarcinoma (PDAC).Prognostic factors are well documented with resectable PDAC, but have not been described detail PDAC therapy.Prospectively collected data consecutive cancer treated by were analyzed. The R status was categorized as R0 (tumor-free >1 mm), R1 ≤1 mm direct...
To investigate the perioperative and oncologic long-term outcomes of patients with LAPC after surgical resection at a high-volume center for pancreatic surgery.The role surgery in arterial involvement is controversial.We analyzed 385 consecutive undergoing PAR (n = 195) or PAD 190) encased artery between January 1, 2003 April 30, 2019.There were 183 total pancreatectomies, 113 partial pancreatoduodenectomies, 79 distal 10 resections tumor recurrences, including 121 multivisceral 171 venous...
Surgical site infections frequently occur after open abdominal surgery. Intraoperative wound irrigation as a preventive measure is common practice worldwide, although evidence supporting this lacking.
NMDA receptors (NMDARs) are essential for modulating synaptic strength at central synapses. At hippocampal CA3-to-CA1 synapses of adult mice, different NMDAR subtypes with distinct functionality assemble from NR1 NR2A and/or NR2B subunits. Here we investigated the role these receptor in long-term potentiation (LTP) induction. Because higher contribution young hippocampus, LTP extracellular field potentials could be enhanced by repeated tetanic stimulation but not mice. Similarly,...
To determine whether circular plastic wound edge protectors (CWEPs) significantly reduce the rate of surgical site infections (SSIs) in comparison to standard towels patients undergoing laparotomy.SSIs cause substantial morbidity, prolonged hospitalization, and costs remain one most frequent complications. CWEPs have been proposed as a measure incidence SSIs.In this randomized controlled, multicenter, 2-arm, parallel-group design, patient- observer-blinded trial open elective abdominal...
The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery not been assessed on a global scale. aim of this study was to evaluate reported checklist use settings and examine the relationship with perioperative mortality patients who had laparotomy.In two multinational cohort studies, adults undergoing laparotomy were compared those having elective gastrointestinal surgery. Relationships between determined using...
Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed describe international variation in drain placement and the safety this practice.COMPASS (COMPlicAted intra-abdominal collectionS Surgery) was prospective, international, cohort which enrolled consecutive adults undergoing (February March 2020). The primary outcome...
The objective of the HASTA trial was to compare hand suture versus stapling loop ileostomy closure in a randomized controlled trial.Bowel obstruction is one main and clinically economically most relevant complication following after low anterior resection. best surgical technique for has not been defined yet.HASTA multicenter pragmatic with 2 parallel groups ileostomy. primary endpoint rate bowel within 30 days closure.A total 337 patients undergoing resection because rectal cancer 27...