Andrew Kirby
A5013391577- Cardiac, Anesthesia and Surgical Outcomes
- Urinary Tract Infections Management
- Viral gastroenteritis research and epidemiology
- Appendicitis Diagnosis and Management
- Surgical site infection prevention
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Viral Infections and Immunology Research
- Antibiotic Use and Resistance
- Colorectal Cancer Surgical Treatments
- Antibiotic Resistance in Bacteria
- Diverticular Disease and Complications
- Infective Endocarditis Diagnosis and Management
- Pediatric Urology and Nephrology Studies
- Pneumonia and Respiratory Infections
- Hepatitis Viruses Studies and Epidemiology
- Antifungal resistance and susceptibility
- Nosocomial Infections in ICU
- Streptococcal Infections and Treatments
- Bacterial biofilms and quorum sensing
- Sepsis Diagnosis and Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Enhanced Recovery After Surgery
- Advanced Thermodynamic Systems and Engines
- Delphi Technique in Research
University of Liverpool
1953-2024
University of Leeds
2015-2024
Royal Hospital for Children
2018-2024
Los Alamos National Laboratory
2023-2024
St James's University Hospital
2024
Leeds Teaching Hospitals NHS Trust
2013-2023
Leeds General Infirmary
2014-2023
University of Göttingen
2022
University of Birmingham
2022
National Institute for Health Research
2022
Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global priority not fully understood. We quantified burden SSI after gastrointestinal surgery in countries all parts world.
Anastomotic leak (AL) is a major complication of rectal cancer surgery. Despite advances in surgical practice, the rates AL have remained static, at around 10-15%. The aetiology multifactorial, but one most crucial risk factors, which mostly under control surgeon, blood supply to anastomosis. MRC/NIHR IntAct study will determine whether assessment anastomotic perfusion using fluorescent dye (indocyanine green) and near-infrared laparoscopy can minimize rate compared with conventional...
Carbapenemase-producing Enterobacteriaceae (CPE), including KPC-producing Klebsiella pneumoniae (KPC-Kpn), are an increasing threat to patient safety. To use WGS investigate the extent and complexity of carbapenemase gene dissemination in a controlled KPC outbreak. with reduced ertapenem susceptibility recovered from rectal screening swabs/clinical samples, during 3 month outbreak (2013–14), were investigated for production, antimicrobial susceptibility, variable-number-tandem-repeat profile...
The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery not been assessed on a global scale. aim of this study was to evaluate reported checklist use settings and examine the relationship with perioperative mortality patients who had laparotomy.In two multinational cohort studies, adults undergoing laparotomy were compared those having elective gastrointestinal surgery. Relationships between determined using...
The detection of norovirus by ELISA and immunochromatographic methods may facilitate epidemiological studies into the global disease burden associated with gastroenteritis provide a quick method testing for infection.To evaluate new RIDASCREEN (3rd generation) RIDAQUICK test on collection samples from Brazilian children acute gastroenteritis, compare them against established 2nd generation IDEIA assay.Reverse transcriptase PCR, study reference standard, was used to 726 specimens presence...
Abstract Rotaviruses and noroviruses are leading viral causes of diarrhoea in children. A cross‐sectional study was undertaken among children aged <5 years with acute gastroenteritis at Al‐Jala Children's Hospital, Tripoli, Libya, from October 2007 to September 2008. Of 1,090 fecal samples collected, 260 inpatients 830 outpatients, all approximately a third selected systematically, were investigated for rotavirus norovirus infection by ELISA real‐time RT‐PCR, respectively. 520 examined...
Internationally, chest radiography is the standard investigation for identifying rib fractures in suspected physical abuse infants. Several small observation studies children have found that CT can provide greater accuracy than fracture detection, potentially aiding medicolegal proceedings cases; however, to our knowledge, this has not been comprehensively evaluated. We aimed determine differences detection rates between post-mortem radiographs and images, using forensic autopsy as reference...
Invasive Escherichia coli disease (IED), including bloodstream infection, sepsis, and septic shock, can lead to high hospitalization mortality rates. This multinational study describes the clinical profile of patients with IED in tertiary care hospitals. We applied criteria systemic inflammatory response syndrome (SIRS), or shock hospitalized culture-confirmed E from urine a presumed sterile site. assessed proposed case definition against physician diagnoses. Most (N = 902) were adults aged...
BackgroundEnd colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation end after left-sided resection.
ObjectivesTo investigate if colonization with heterogeneous glycopeptide-intermediate Staphylococcus aureus (hGISA) is associated hGISA bacteraemia.
To describe the epidemiology of rotavirus and norovirus infection among children with acute gastroenteritis in Sana'a, Yemen.A cross-sectional study from November 2007 to March 2009 aged 1 month 5 years attending emergency outpatient departments two hospitals Sana'a gastroenteritis. Rotavirus was detected by ELISA genotyped RT-PCR. Norovirus End Point RT-PCR nucleotide sequencing.A total 290 (48% department 52% respectively) were enrolled. infections 78 (27%) 30 (10%). genotypes included...
Background: Gastro-enteritis is associated with significant mortality in low- and middle-income countries, rotavirus norovirus are the principal viral agents implicated.Aims: To investigate molecular epidemiology burden of disease children attending a health centre Ethiopia.Methods: A cross-sectional study was conducted Awassa, southern Ethiopia. Children diarrhoea (cases) without (controls) were recruited over 6-month period from December 2008 to May 2009. Rotavirus detected by ELISA...
The aim of this study is to investigate if correlations exist between income inequality and antimicrobial resistance. This study's hypothesis that at the national level positively correlated with resistance within developed countries.Income data were obtained from Standardized World Income Inequality Database. Antimicrobial European Resistance Surveillance Network outpatient consumption data, measured by Defined daily Doses per 1000 inhabitants day, Consumption group. Spearman's correlation...