Radhian Amandito
A5012412539- Cardiac, Anesthesia and Surgical Outcomes
- Neonatal Health and Biochemistry
- Infant Nutrition and Health
- Public Health and Nutrition
- Global Health and Surgery
- Enterobacteriaceae and Cronobacter Research
- Appendicitis Diagnosis and Management
- Gut microbiota and health
- Methemoglobinemia and Tumor Lysis Syndrome
- Heme Oxygenase-1 and Carbon Monoxide
- Colorectal Cancer Surgical Treatments
- Erythrocyte Function and Pathophysiology
- Hemoglobinopathies and Related Disorders
- Surgical site infection prevention
- Pluripotent Stem Cells Research
- Child Nutrition and Water Access
- Diverticular Disease and Complications
- Global Health Workforce Issues
- Hormonal Regulation and Hypertension
- Advances in Oncology and Radiotherapy
- Biomedical Ethics and Regulation
- Colorectal Cancer Screening and Detection
- COVID-19 and healthcare impacts
- Hip and Femur Fractures
- Nerve injury and regeneration
University of Edinburgh
2024
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2018-2022
University of Indonesia
2015-2022
American Academy of Pediatrics
2018
Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global priority not fully understood. We quantified burden SSI after gastrointestinal surgery in countries all parts world.
Background80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative breast, colorectal, gastric surgery hospitals worldwide, focusing the effect disease stage complications mortality.MethodsThis was multicentre, international prospective cohort study consecutive adult patients undergoing for primary or requiring skin incision done under general neuraxial...
Abstract Background Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in availability of laparoscopic appendectomy, alternative management choices, outcomes are poorly described. The aim was to identify variation appendicitis within low-, middle-, high-Human Development Index (HDI) countries Methods This a multicenter, international prospective cohort study. Consecutive sampling patients undergoing appendectomy over 6...
This study compares the minimally invasive Bilistick and a noninvasive method with standard Total Serum Bilirubin (TSB) measurement in preterm newborns receiving phototherapy. We assess agreement of Transcutaneous Bilirubinometer (TcB) bilirubin measurements TSB infants was measured by using TcB 94 RSCM Jakarta Neonatal Ward from October 2016 to March 2017, gestational ages < 35 weeks, before phototherapy after 24 48 h There significant correlation before, at between either (r = 0.874; r...
BackgroundEnd colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation end after left-sided resection.
Background: Single nucleotide polymorphism (SNP) variants of the uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) gene have been studied as an important factor in neonatal hyperbilirubinemia (jaundice) severity. Specific ethnicities, including Asians, certain SNPs that appear more frequently than others. Aim: To identify most common Indonesian neonates and their association with severity hyperbilirubinemia. Methods: Eighty-eight inborn outborn jaundiced infants from three different...
Abstract Background Identification of patients at high risk surgical-site infections may allow surgeons to minimize associated morbidity. However, there are significant concerns regarding the methodological quality and transportability models previously developed. The aim this study was develop a novel score predict 30-day infection after gastrointestinal surgery across global context externally validate against existing models. Methods This secondary analysis two prospective international...
The genetic involvement in unconjugated neonatal hyperbilirubinemia has been extensively studied. Despite the high incidence of Indonesia, studies are lacking. objective this study is to elucidate role polymorphism UGT1A1 Neonatal Hyperbilirubinemia Bengkulu, Indonesia. There were 41 neonates enrolled study; 30 had a total serum bilirubin level ≥ 15 mg/dL (hyperbilirubinemia neonates) while 11 < (control neonates). Genetic mutations Exon 1, UGT1A1*6 (c211g > a) and one promoter region,...
Abstract Determining the initial normal neonatal gut microbiome is challenging. The debate regarding sterile fetal environment still ongoing. Therefore, studying and comparing dysbiotic microbiomes requires elucidation of both infant microbiomes. Factors influencing also include regional genetic factors specific to different countries. population in our center their association with clinical conditions infants helpful as a tool for prevention treatment related diseases during care. Here, we...
It has been established that genetic factors play a substantial role in the development of neonatal hyperbilirubinemia. The population Indonesia and other Southeast Asian countries similar, yet different makeup compared to rest Asia. Aside from UGT1A1, variants SLCO1B1 have also known contribute severity hyperbilirubinemia populations. Since there no report on polymorphism relation with Indonesia, this study aims explore incidence SLCO1B1*1B based 3 hospitals provinces population, their...
Pada bayi baru lahir terjadi kenaikan fisiologis kadar bilirubin dan 60% >35 minggu akan terlihat ikterik. Namun, 3%-5% dari kejadian ikterik tersebut tidaklah berisiko untuk terjadinya kerusakan neurologis bahkan kematian. Sebagai pencegahan hiperbilirubinemia berat yang dapat menyebabkan neurologis, pemeriksaan telah menjadi rekomendasi universal kuning. Semakin tinggi perhatian klinisi kernikterus, semakin rendah insidensinya. Indonesia menghadapi masalah overtreatment di perkotaan,...
Microbial colonization of a neonate's gastrointestinal tract has significant perinatal and lifetime health consequences. However, information regarding the profile meconium microbiota in neonates influence clinical parameters are lacking Indonesian population. This study aimed to preliminary investigate cultivable bacterial diversity isolated from born at Cipto Mangunkusumo Hospital (CMH), Jakarta. The bacteria were samples then processed for cultivation molecular identification.Fourteen...
Background Uridine diphospho-glucuronocyltransferase 1A1 (UGT1A1) polymorphisms are a risk factor for unconjugated hyperbilirubinemia in neonates. UGT1A1 decrease bilirubin conjugation, thus causing hyperbilirubinemia. A variety of have been reported, with UGT1A1*60 and UGT1A1*6 especially prominent the Asian population. Hyperbilirubinemia polymorphism studies lacking Indonesian populations. Objective To identify profiles populations heterogeneous ethnicity. Methods We enrolled 42 jaundiced...
Bayi prematur memiliki risiko lebih tinggi untuk terjadinya gagal tumbuh dan kembang dibandingkan bayi aterm. Intervensi yang diperlukan penting terutama selama 1000 hari pertama kelahiran. Risiko penyakit metabolik, obesitas, kardiovaskuler, gangguan kembang, merupakan beberapa dari dampak negatif bila pemberian nutrisi ridak optimal di pertama. Indonesia salah satu negara dengan masalah stunting. Stunting bisa dicegah adekuat serta pemantauan rutin baik grafik khusus prematur. Selama...
Komposisi mikrobioma usus pada neonatus prematur dapat diidentifikasi dari mekonium dan feses dengan teknologi Next-Generation Sequencing (NGS). Akan tetapi, perolehan DNA sampel memiliki tantangan karena konsistensi serta kandungan inhibitor PCR yang tinggi tersebut. Tujuan penelitian ini adalah untuk mengoptimasi neonatus. Proses dilakukan menerapkan optimasi parameter yaitu pertimbangan tahap pra-ekstraksi replikasi kondisi sampel, penggunaan pilihan kit ekstraksi, elusi hasil ekstraksi....
Microbial colonization of a neonate’s gastrointestinal tract has significant perinatal and lifetime health consequences, with some clinical outcomes that have been linked to differences in the diversity composition gut microbiota. The effort engineer intestinal ecosystem led us preserve cultivable commensal Here we investigated association bacterial neonates meconium from Indonesian National Referral Hospital Cipto Mangunkusumo (NRHCM) mode delivery feeding patterns, as well...
Bayi prematur memiliki risiko lebih tinggi untuk terjadinya gagal tumbuh dan kembang dibandingkan bayi aterm. Intervensi yang diperlukan penting terutama selama 1000 hari pertama kelahiran. Risiko penyakit metabolik, obesitas, kardiovaskuler, gangguan kembang, merupakan beberapa dari dampak negatif bila pemberian nutrisi ridak optimal di pertama. Indonesia salah satu negara dengan masalah stunting. Stunting bisa dicegah adekuat serta pemantauan rutin baik grafik khusus prematur. Selama...