Nina M. Clark

ORCID: 0000-0002-1573-554X
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About
Contact & Profiles
Research Areas
  • Trauma and Emergency Care Studies
  • Ovarian function and disorders
  • Uterine Myomas and Treatments
  • Genetic factors in colorectal cancer
  • BRCA gene mutations in cancer
  • Gynecological conditions and treatments
  • Reproductive Biology and Fertility
  • Pelvic and Acetabular Injuries
  • Burn Injury Management and Outcomes
  • Cancer Genomics and Diagnostics
  • Abdominal Trauma and Injuries
  • Endometriosis Research and Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Ovarian cancer diagnosis and treatment
  • Healthcare Policy and Management
  • Autopsy Techniques and Outcomes
  • Disaster Response and Management
  • Emergency and Acute Care Studies
  • Cardiac electrophysiology and arrhythmias
  • Tracheal and airway disorders
  • Dental Education, Practice, Research
  • Surgical site infection prevention
  • Health disparities and outcomes
  • Workplace Health and Well-being
  • Hip and Femur Fractures

University of Washington
2022-2025

Loyola University Chicago
2025

University of Edinburgh
2024

Seattle University
2022

University of California, San Francisco
2015-2018

Tufts Medical Center
2016

Cornell University
2012-2014

Queen Alexandra Hospital
2005

Background: Studies of out-of-hospital cardiac arrest and sudden death (SCD) use emergency medical services records, certificates, or definitions that infer cause death; thus, the true incidence SCD is unknown. Over 90% SCDs occur out-of-hospital; nonforensic autopsies are rarely performed, therefore causes presumed. We conducted a examiner–based investigation to determine precise autopsy-defined all in an entire metropolitan area. hypothesized postmortem would identify actual arrhythmic...

10.1161/circulationaha.117.033427 article EN Circulation 2018-06-18

Background Cytokine release triggered by a hyperactive immune response is thought to contribute severe acute respiratory syndrome coronavirus 2019 (SARS-CoV-2)–related failure. Bruton tyrosine kinase (BTK) involved in innate immunity, and BTK inhibitors block cytokine release. We assessed the next-generation inhibitor zanubrutinib SARS-CoV-2–infected patients with distress. Method Cohort 1 had prospective, randomized, double-blind, placebo-controlled design; cohort 2 single-arm design....

10.3389/fimmu.2024.1369619 article EN cc-by Frontiers in Immunology 2025-01-21

<h3>Importance</h3> Interrogations and autopsies of sudden deaths with cardiac implantable electronic devices (CIEDs) are rarely performed. Therefore, causes these the incidence device failure unknown. <h3>Objective</h3> To determine death in individuals CIEDs a prospective autopsy study all over 35 months as part San Francisco, California, Postmortem Systematic Investigation Sudden Cardiac Death (POST SCD) study. <h3>Design, Setting, Participants</h3> Full autopsy, toxicology, histology,...

10.1001/jamainternmed.2015.2641 article EN JAMA Internal Medicine 2015-06-22

Studies have suggested that polycystic ovary syndrome (PCOS) is associated with increased cardiovascular risk. The aim of this study was to examine risk profiles in women PCOS compared healthy age and weight matched control subjects using novel biochemical biophysical markers.After ethics committee approval, 11 12 controls were recruited (mean age, 32; SD, 6.5 years; mean body mass index (BMI), 33.1; 5.9 kg/m2). Serum analysed for lipid lipoprotein profile (total high density cholesterol,...

10.1136/jcp.2003.015271 article EN Journal of Clinical Pathology 2005-01-27

Importance Timely access to care is a key metric for health systems and particularly important in conditions that acutely worsen with delays care, including surgical emergencies. However, the association between travel time emergency risk complex presentation poorly understood. Objective To evaluate impact of on disease complexity at among people general surgery whether was associated clinical outcomes measures increased resource utilization. Design, Setting, Participants This retrospective...

10.1001/jamanetworkopen.2024.55258 article EN cc-by-nc-nd JAMA Network Open 2025-01-21

BACKGROUND National estimates of financial hardship because injury are lacking, which limits our ability to both define and mitigate the impacts outcomes trauma care. Furthermore, absence preinjury data understanding association between hardship. METHODS We analyzed from 2014–2021 Medical Expenditure Panel Survey. compared injured adults (18–64 years old) uninjured controls using coarsened-exact matching on age, sex, race/ethnicity, income, payer, survey panel, comorbidities. Our main...

10.1097/ta.0000000000004545 article EN Journal of Trauma and Acute Care Surgery 2025-02-06

Objective: We sought to evaluate associations between rural training exposure during surgical residency and eventual practice in a community, whether specific types of were more likely yield surgeons. Background: Growing deficits the surgery workforce have prompted increased attention toward training. However, association communities remains limited. Methods: performed retrospective cohort study US general graduates from 2011-2020. Program information was abstracted websites, American...

10.1097/sla.0000000000006696 article EN Annals of Surgery 2025-03-19

Objective: To describe the experience of uninsured and Medicaid Oregon tobacco users who registered in Free &amp; Clear (F&amp;C), a telephone based cessation programme including five scheduled outbound calls. Design setting: Using retrospective cohort design, 1334 (423 uninsured, 806 Medicaid, 105 commercially insured) F&amp;C between 18 November 1998 28 February 2000 were identified followed for 12 months post-registration; 648 (48.6%) successfully contacted at months. Information was...

10.1136/tc.12.1.45 article EN Tobacco Control 2003-02-28

To evaluate the association between U.S. Food and Drug Administration (FDA) communication discouraging use of power morcellators on changes in surgical practice for women with uterine leiomyomas.This is a cross-sectional study using data from 2013 to 2014 Healthcare Cost Utilization Project State Inpatient Ambulatory Surgical Databases Arizona, Florida, Kentucky, New Jersey. Women diagnosis leiomyomas who underwent hysterectomy or myomectomy were included analysis. Multivariable models used...

10.1097/aog.0000000000002309 article EN Obstetrics and Gynecology 2017-10-10

We compared the Ambu aScope™ with a conventional fibrescope in two simulated settings. First, 22 volunteers performed paired oral and nasal fibreoptic intubations three different manikins: Laerdal Airway Trainer, Bill 1 Airsim (a total of 264 intubations). Second, 21 intubated Trainer manikin via supraglottic airways: classic intubating laryngeal mask airways i-gel 66 Performance aScope was good few failures infrequent problems. In first study, choice had an impact on number user-reported...

10.1111/j.1365-2044.2011.06647.x article EN Anaesthesia 2011-02-24

Abstract Background Identification of patients at high risk surgical-site infections may allow surgeons to minimize associated morbidity. However, there are significant concerns regarding the methodological quality and transportability models previously developed. The aim this study was develop a novel score predict 30-day infection after gastrointestinal surgery across global context externally validate against existing models. Methods This secondary analysis two prospective international...

10.1093/bjs/znae129 article EN cc-by British journal of surgery 2024-06-01

BACKGROUND Early transfer to specialized centers improves trauma and burn outcomes; however, overtriage can result in unnecessary burdens patients, providers, health systems. Our institution developed novel triage pathways 2016 improve resource allocation. We evaluated the implementation of these pathways, analyzing trends adoption, optimization, pathway reliability after implementation. METHODS Triage consist nurses (RNs) triaging calls based on review images clinical history: green for...

10.1097/ta.0000000000004202 article EN Journal of Trauma and Acute Care Surgery 2023-12-21

10.1016/j.annemergmed.2024.08.328 article EN Annals of Emergency Medicine 2024-09-25

This Viewpoint highlights the need for standardization in rural surgery training and suggests specific strategies to address this issue.

10.1001/jamasurg.2024.3403 article EN JAMA Surgery 2024-10-23

Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine condition associated with risk of infertility and endometrial hyperplasia. Women PCOS demonstrate varying degrees menstrual cycle dysfunction ranging from frank oligo-amenorrhea to regular cycles. Variations in status suggest differences significant fertility potential long-term health risks for women milder phenotypes. The establishment ovulatory anovulatory phenotypes warrants better understanding development PCOS. present study...

10.1093/biolreprod/87.s1.344 article EN Biology of Reproduction 2012-08-01
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