- Congenital gastrointestinal and neural anomalies
- Intestinal Malrotation and Obstruction Disorders
- Esophageal and GI Pathology
- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Tracheal and airway disorders
- Congenital Anomalies and Fetal Surgery
- Gastrointestinal disorders and treatments
- Congenital Diaphragmatic Hernia Studies
- Appendicitis Diagnosis and Management
- Pediatric Hepatobiliary Diseases and Treatments
- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Inflammatory Bowel Disease
- Hernia repair and management
- Intestinal and Peritoneal Adhesions
- Diverticular Disease and Complications
- Microscopic Colitis
- Urological Disorders and Treatments
- Diet and metabolism studies
- Dysphagia Assessment and Management
- Cystic Fibrosis Research Advances
- Childhood Cancer Survivors' Quality of Life
- Abdominal Surgery and Complications
- Child Nutrition and Feeding Issues
Royal Children's Hospital
2016-2025
Murdoch Children's Research Institute
2016-2025
The University of Melbourne
2016-2025
Children's Hospital Foundation
2024
The Royal Children's Hospital Foundation
2024
The University of Sydney
2012-2024
Royal Ottawa Mental Health Centre
2024
Heilbronn University
2024
University of Edinburgh
2022
Hospital for Sick Children
2002-2020
Abstract Background Slow‐transit constipation (STC) is recognized in children but the etiology unknown. Abnormalities substance P (SP), vasoactive intestinal peptide (VIP) and nitric oxide (NO) have been implicated. The density of nerve fibers circular muscle containing these transmitters was examined colon from with STC compared to other pediatric adult samples. Methods Fluorescence immunohistochemistry using antibodies NO synthase (NOS), VIP SP performed on colonic biopsies (transverse...
Intraoperative hypercapnia and acidosis have been associated with thoracoscopic repair of both congenital diaphragmatic hernia esophageal atresia/tracheoesophageal fistula.The aim the present study was to investigate whether or fistula in a large group neonates, analyze effects on early postoperative outcomes.We reviewed charts neonates who underwent open (2004-2014). Patients available intraoperative arterial gas values were included. Data (PaCO2 : mm Hg) compared using paired/unpaired...
objectives were to investigate the relations between associated anomalies and ARM types, timing of reconstructive surgery. Subjects data collectionARM patients under 18 years age treated in one ARM-Net Consortium registered registry until 1 March 2023 included.Each centre has a lead paediatric surgeon who is responsible for patient registration collection at their respective centre.Patient are de-identified pseudonymized before collection.Surgeons can only re-identify own with personal...
Abstract Objectives Esophageal atresia (EA) is a significant congenital anomaly, with most survivors experiencing esophageal dysmotility. Currently, there no reliable way to predict which patients will develop significant, life‐threatening Using high‐resolution impedance manometry (HRIM), this study aimed characterize the common pressure topography patterns in children repaired EA. Methods This prospective longitudinal cohort focused on (<18 years) Utilizing HRIM, motility were studied....
BACKGROUND The physiological basis of slow transit constipation (STC) in children remains poorly understood. We wished to examine pan-colonic motility a group with severe chronic refractory conservative therapy. METHODS performed 24 h manometry 18 (13 boys, 11.6 ± 0.9 yr, range 6.6–18.7 yr) scintigraphically proven STC. A water-perfused, balloon tipped, 8-channel, silicone catheter 7.5 cm intersidehole distance was introduced through previously formed appendicostomy. Comparison data were...
Background Anorectal malformations (ARM) are common congenital abnormalities of the terminal hindgut. The high incidence associated anomalies necessitates systematic screening, which should include renal and spinal ultrasonography, radiography an echocardiogram. This study aimed to determine in ARM, whether screening protocols were appropriately applied. Methods A retrospective review was performed all ARM patients managed at Royal Children's Hospital, Melbourne over a 16‐year period...