- Intestinal Malrotation and Obstruction Disorders
- Infant Nutrition and Health
- Appendicitis Diagnosis and Management
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Neonatal Respiratory Health Research
- Congenital Anomalies and Fetal Surgery
- Congenital Diaphragmatic Hernia Studies
- Delphi Technique in Research
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- Social Work Education and Practice
- Hernia repair and management
- Intestinal and Peritoneal Adhesions
- Clinical Nutrition and Gastroenterology
- Breastfeeding Practices and Influences
- Congenital gastrointestinal and neural anomalies
- Education and Technology Integration
- Gastrointestinal disorders and treatments
- Urological Disorders and Treatments
- Child Nutrition and Feeding Issues
- Viral gastroenteritis research and epidemiology
- Social Policy and Reform Studies
- Foreign Body Medical Cases
- Early Childhood Education and Development
Southampton Children's Hospital
2016-2025
University of Southampton
2016-2025
Southampton General Hospital
1998-2025
Alder Hey Children's NHS Foundation Trust
2025
University Hospital Southampton NHS Foundation Trust
2013-2024
Janssen (United States)
2024
NIHR Southampton Biomedical Research Centre
2024
University of Hertfordshire
2023
University College London
2006-2022
EES Research (United Kingdom)
2013-2022
The aim of this study was to evaluate the feasibility and safety nonoperative treatment acute nonperforated appendicitis with antibiotics in children.A pilot randomized controlled trial performed comparing versus surgery for children. Patients imaging-confirmed who would normally have had emergency appendectomy were either or surgery. Follow-up 1 year.Fifty patients enrolled; 26 24 antibiotics. All children group histopathologically confirmed appendicitis, there no significant complications...
While non-operative treatment has emerged as an alternative to surgery for the of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these a feasibility randomised trial. Of 57 participants, data were available 26. Compared with appendicectomy, children allocated reported higher short-term quality life scores, shorter duration requiring analgesia, more rapid return normal activities and parental absence from work. These...
Language brokering describes the task in an intercultural language event undertaken by children families with one or two non-national languaged parents caregivers. This paper examines complex issues involved being a broker and explores these as they apply to group of adolescents Chinese UK. The findings show that for activities undertake are not only demanding, but make significant economic contribution family life.
The aim of this study was to investigate the factors associated with mortality in infants referred for surgical treatment advanced necrotizing enterocolitis (NEC).Retrospective review all confirmed (Bell stage II or III) NEC treated our unit during past 8 years (January 2002 December 2010). Data survivors and nonsurvivors were compared using Mann-Whitney test Fisher's exact are reported as median (range).Of 205 NEC, 35 (17%) medically managed; 170 (83%) had surgery; 66 (32%) died; received...
The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery not been assessed on a global scale. aim of this study was to evaluate reported checklist use settings and examine the relationship with perioperative mortality patients who had laparotomy.In two multinational cohort studies, adults undergoing laparotomy were compared those having elective gastrointestinal surgery. Relationships between determined using...
Objective Congenital duodenal obstruction (CDO) comprising atresia or stenosis is a rare congenital anomaly requiring surgical correction in early life. Identification of variation and postoperative practice previous studies has been limited by small sample sizes. This study aimed to prospectively estimate the incidence CDO UK, report current management strategies short-term outcomes. Design Prospective population-based, observational for 12 months from March 2016. Setting Specialist...
Abstract Background Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in availability of laparoscopic appendectomy, alternative management choices, outcomes are poorly described. The aim was to identify variation appendicitis within low-, middle-, high-Human Development Index (HDI) countries Methods This a multicenter, international prospective cohort study. Consecutive sampling patients undergoing appendectomy over 6...