- Intestinal Malrotation and Obstruction Disorders
- Congenital Diaphragmatic Hernia Studies
- Congenital Anomalies and Fetal Surgery
- Congenital gastrointestinal and neural anomalies
- Esophageal and GI Pathology
- Urological Disorders and Treatments
- Gastrointestinal disorders and treatments
- Hernia repair and management
- Appendicitis Diagnosis and Management
- Pediatric Hepatobiliary Diseases and Treatments
- Abdominal Trauma and Injuries
- Intestinal and Peritoneal Adhesions
- Pelvic floor disorders treatments
- Clinical Nutrition and Gastroenterology
- Neonatal Respiratory Health Research
- Tracheal and airway disorders
- Pleural and Pulmonary Diseases
- Diverticular Disease and Complications
- Tumors and Oncological Cases
- Gastroesophageal reflux and treatments
- Inflammatory Bowel Disease
- Gallbladder and Bile Duct Disorders
- Vascular Malformations and Hemangiomas
- Bariatric Surgery and Outcomes
- Trauma Management and Diagnosis
Hospital for Sick Children
2016-2025
University of Toronto
2016-2025
SickKids Foundation
2016-2025
McMaster Children's Hospital
1996-2025
King Abdulaziz University
2025
Children's Hospital of Eastern Ontario
2025
University of British Columbia
2025
University of Alberta
2025
Nationwide Children's Hospital
2021-2024
Centre for Social Innovation
2021
The Food and Drug Administration recently approved the use of palivizumab (pal-vizh-mäb), an intramuscularly administered monoclonal antibody preparation. Recommendations for its are based on a large, randomized study demonstrating 55% reduction in risk hospitalization attributable to respiratory syncytial virus (RSV) infections high-risk pediatric patients. Infants children with chronic lung disease (CLD), formerly designated bronchopulmonary dysplasia, as well prematurely born infants...
Perforated necrotizing enterocolitis is a major cause of morbidity and mortality in premature infants, the optimal treatment uncertain. We designed this multicenter randomized trial to compare outcomes primary peritoneal drainage with laparotomy bowel resection preterm infants perforated enterocolitis.We randomly assigned 117 (delivered before 34 weeks gestation) birth weights less than 1500 g at 15 pediatric centers undergo or resection. Postoperative care was standardized. The outcome...
Summary Guidelines on hereditary spherocytosis (HS) published in 2004 (Bolton‐Maggs et al , 2004) are here replaced to reflect changes current opinion the surgical management, (particularly indications for concomitant splenectomy with cholecystectomy children mild HS, and those asymptomatic gallstones). Further potential long term hazards of now recognised. Advances have been made our understanding biochemistry red cell membrane which underpins choice tests. Biochemical assays membranes...
Interleukin-10 (IL-10) signaling genes are attractive inflammatory bowel disease (IBD) candidate as IL-10 restricts intestinal inflammation, polymorphisms have been associated with IBD in genome-wide association studies, and mutations receptor (IL-10R) reported immunodeficient children severe infantile-onset IBD. Our objective was to determine if IL-10R were early-onset (EO-IBD) very-early-onset (VEO-IBD).Candidate-gene analysis of IL10RA IL10RB performed after initial sequencing an...
In Brief Background: The surgical management of Hirschsprung's disease (HD) has evolved from the original 3-stage approach to recent introduction minimal-access single-stage techniques. We reviewed early results transanal Soave pullthrough 6 centers use it. Methods: clinical course all children with HD undergoing a 1-stage between 1995 and 2002 were reviewed. Children preliminary stoma or total colonic excluded. Results: There 141 patients. Mean time diagnosis surgery was 32 days, mean age...
Since 1967, 40 patients with hydatid disease of the liver have been treated at our hospital. Diagnosis was made using clinical criteria, serology, skin tests, and imaging techniques. Thirty-five were operated upon. In 18 cyst uncomplicated (Group I), in 17 infected or communicated biliary tract II). Three forms surgical treatment used: A) evacuation, scolicidal irrigation, primary closure, B) external drainage, C) complete partial resection. Mebendazole used six patients, four whom also...