Cherry Koh
- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal and Anal Carcinomas
- Intraperitoneal and Appendiceal Malignancies
- Anorectal Disease Treatments and Outcomes
- Hernia repair and management
- Appendicitis Diagnosis and Management
- Pelvic floor disorders treatments
- Enhanced Recovery After Surgery
- Cancer survivorship and care
- Colorectal Cancer Screening and Detection
- Nutrition and Health in Aging
- Delphi Technique in Research
- Ovarian cancer diagnosis and treatment
- Pelvic and Acetabular Injuries
- Colorectal Cancer Treatments and Studies
- Diverticular Disease and Complications
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- COVID-19 and healthcare impacts
- Clinical practice guidelines implementation
- Frailty in Older Adults
- Uterine Myomas and Treatments
- Pain Management and Opioid Use
- Hip and Femur Fractures
The University of Sydney
2016-2025
Royal Prince Alfred Hospital
2016-2025
Sydney Local Health District
2014-2024
Cooperative Trials Group for Neuro-Oncology
2018-2024
Southampton General Hospital
2023
University of Southampton
2023
Basingstoke and North Hampshire Hospital
2023
University of Iowa Hospitals and Clinics
2023
University of Minnesota
2023
Ospedale Papa Giovanni XXIII
2023
Consensus abstract Background The management of primary rectal cancer beyond total mesorectal excision planes (PRC-bTME) and recurrent (RRC) is challenging. There global variation in standards no guidelines exist. To achieve cure most patients require extended, multivisceral, exenterative surgery, conventional planes. aim the Beyond TME Group was to consensus on definitions principles management, identify areas research priority. Methods Delphi methodology used consensus. consisted invited...
Consensus abstract Background The management of primary rectal cancer beyond total mesorectal excision planes (PRC-bTME) and recurrent (RRC) is challenging. There global variation in standards no guidelines exist. To achieve cure most patients require extended, multivisceral, exenterative surgery, conventional planes. aim the Beyond TME Group was to consensus on definitions principles management, identify areas research priority. Methods Delphi methodology used consensus. consisted invited...
Abstract Background Pelvic exenteration for locally recurrent rectal cancer (LRRC) is associated with variable outcomes, the majority of data from single-centre series. This study analysed an international collaboration to determine robust parameters that could inform clinical decision-making. Methods Anonymized on patients who had pelvic LRRC between 2004 and 2014 were accrued 27 specialist centres. The primary endpoint was survival. impact resection margin, bone resection, node status use...
Objective: To assess the outcomes and patterns of treatment failure patients who underwent pelvic exenteration surgery for recurrent rectal cancer. Background: Despite advances in management cancer, local recurrence still occurs. For appropriately selected patients, can achieve long-term disease control. Methods: Prospectively maintained databases 5 high volume institutions were reviewed data combined. We assessed combined endpoints overall 5-year survival, cancer-specific mortality,...
Pelvic exenteration was first described by Alexander Brunschwig in 1948 New York as a palliative procedure for recurrent carcinoma of the cervix. Because initially high rates morbidity and mortality, practice this ultraradical operation largely confined to small number American centers most 20 century. The post-World War II era saw advances anaesthesia, blood transfusion, intensive care medicine that would facilitate evolution more radical heroic abdominal pelvic surgery. In last 3 decades,...
Abstract Background Pelvic exenteration is highly radical surgery offering the only potential cure for locally advanced pelvic cancer. This study compared quality of life and other relevant patient-reported outcomes over 12 months patients who did those not undergo exenteration. Methods Consecutive referred consideration completed clinical outcome assessments at baseline, hospital discharge (exenteration only), 1, 3, 6, 9 months. Outcomes included cancer-specific (Functional Assessment...
Pelvic exenteration (PE) is the preferred treatment available for selected patients diagnosed with locally advanced or recurrent cancer confined to pelvis. Currently, majority of literature reports only on short-term survival and quality-of-life (QoL) outcomes. The aim this prospective cohort study was describe long-term QoL outcomes following PE. This a consecutive undergoing PE from 1994 2016 at major teaching hospital in Sydney, Australia. From 2008, consenting were also included study....
Recently, the number of prehabilitation trials has increased significantly. The identification key research priorities is vital in guiding future directions. Thus, aim this collaborative study was to define for patients undergoing cancer surgery.The Delphi methodology implemented over three rounds surveys distributed experts from across multiple specialties, tumour streams and countries via a secure online platform. In first round, participants were asked provide baseline demographics...
Abstract Background Involvement of the lateral compartment remains a relative or absolute contraindication to pelvic exenteration in most units. Initial experience with authors' unit produced 21 per cent clear margin rate (R0), which improved 53 by adopting novel technique for en bloc resection iliac vessels and other side-wall structures. The objective this study was report morbidity oncological outcomes consecutive exenterations involving compartment. Methods Patients undergoing between...
BackgroundPelvic exenteration for locally advanced rectal cancer (LARC) and recurrent (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes over time.
Abstract Background Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in availability of laparoscopic appendectomy, alternative management choices, outcomes are poorly described. The aim was to identify variation appendicitis within low-, middle-, high-Human Development Index (HDI) countries Methods This a multicenter, international prospective cohort study. Consecutive sampling patients undergoing appendectomy over 6...
Abstract Background Pelvic exenteration (PE) provides a potentially curative option for advanced or recurrent malignancy confined to the pelvis. A clear (R0) resection margin is strongest prognostic factor predicting long-term survival, driving most technical advances in PE surgery. The aim of this cohort study was describe changing trends extent resection, postoperative complications, mortality and overall survival after Methods Consecutive patients who underwent pelvic at single...
To determine surgical, survival and quality of life outcomes across different tumour streams lessons learned over 28 years.Consecutive patients undergoing pelvic exenteration at a single, high volume, referral hospital, between 1994 2022 were included. Patients grouped according to their type presentation as follows, advanced primary rectal cancer, other malignancy, locally recurrent malignancy non-malignant indications. The main included, resection margins, postoperative morbidity,...
Advanced pelvic cancers involving the lateral compartment, and particularly iliac vasculature, are difficult to manage. Common or external vessel involvement has traditionally been considered a contraindication for curative surgery.The purpose of this study was investigate pathological surgical outcomes, postoperative morbidity exenteration with en bloc major vascular excision reconstruction.This case series.The conducted at quaternary referral center in Sydney.Patients included those...
Considerable progress has been made in the management of patients with locally advanced or recurrent cancers pelvis over past 60 years since inception pelvic exenteration. Early exenteration was marred by high surgical mortality and morbidity, which drew scepticism from broader community. Subsequent evolution procedure hinged on establishing safety a better understanding outcome predictors. Surgical is now comparable to that elective resection for primary colorectal cancers. The importance...
Abstract Objective To establish the feasibility and acceptability of a preoperative exercise program, to obtain pilot data on likely difference in key surgical outcomes inform sample size calculation for full-scale trial. Design Pilot randomized controlled Setting Royal Prince Alfred Hospital, Sydney, Australia. Subjects We included patients undergoing elective pelvic exenteration or cytoreductive surgery aged 18 80 years, who presented participating gastrointestinal surgeon at least 2 weeks...
Abstract Background Radical surgery is the mainstream treatment for patients presenting with advanced primary or recurrent gastrointestinal cancers; however, rate of postoperative complications exceptionally high. The current evidence suggests that improving patients’ fitness during preoperative period may enhance recovery. Thus, aim this study to establish effectiveness prehabilitation a progressive, individualised, exercise and education program compared usual care alone in reducing...