Jacobus W. A. Burger
- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Intraperitoneal and Appendiceal Malignancies
- Colorectal Cancer Screening and Detection
- Appendicitis Diagnosis and Management
- Hernia repair and management
- Colorectal Cancer Treatments and Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Anorectal Disease Treatments and Outcomes
- Ovarian cancer diagnosis and treatment
- Gastric Cancer Management and Outcomes
- Pelvic and Acetabular Injuries
- Radiomics and Machine Learning in Medical Imaging
- Intestinal and Peritoneal Adhesions
- Genetic factors in colorectal cancer
- Frailty in Older Adults
- Pelvic floor disorders treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Stoma care and complications
- Nutrition and Health in Aging
- Neuroendocrine Tumor Research Advances
- Advanced Radiotherapy Techniques
- Multiple and Secondary Primary Cancers
- Enhanced Recovery After Surgery
- Occupational and environmental lung diseases
Catharina Ziekenhuis
2018-2025
Radboud University Nijmegen
2018-2025
Maastricht University
2021-2025
Cancer Center Amsterdam
2024
University of Amsterdam
2024
Cancer Institute (WIA)
2024
Wisconsin Institutes for Discovery
2024
University of Wisconsin–Madison
2024
Amsterdam University Medical Centers
2024
Southampton General Hospital
2023
The objective of this study was to determine the best treatment incisional hernia, taking into account recurrence, complications, discomfort, cosmetic result, and patient satisfaction.Long-term results hernia repair are lacking. Retrospective studies midterm indicate that mesh is superior suture repair. However, many surgeons still performing repair.Between 1992 1998, a multicenter trial performed, in which 181 eligible patients with primary or first-time recurrent midline were randomly...
Abstract Background The association between body composition (e.g. sarcopenia or visceral obesity) and treatment outcomes, such as survival, using single‐slice computed tomography (CT)‐based measurements has recently been studied in various patient groups. These studies have conducted with different software programmes, each their specific characteristics, of which the inter‐observer, intra‐observer, inter‐software correlation are unknown. Therefore, a comparative study was performed....
Abstract Background Pelvic exenteration for locally recurrent rectal cancer (LRRC) is associated with variable outcomes, the majority of data from single-centre series. This study analysed an international collaboration to determine robust parameters that could inform clinical decision-making. Methods Anonymized on patients who had pelvic LRRC between 2004 and 2014 were accrued 27 specialist centres. The primary endpoint was survival. impact resection margin, bone resection, node status use...
Aim Comparison of transanal excision (TE) and endoscopic microsurgery (TEM) rectal adenomas (RA) has rarely been performed. Method From 1990 to 2007, the results TE (43 RA) TEM (216 were compared. Rectal matched for diameter distance from anal verge. Results Operation time was 47.5 min 35 (P < 0.001). Morbidity 10% after 5.3% Negative resection margins observed in 50% 88% Fragmentation excised specimen 23.8% 1.4% In cases fragmentation, positive more frequently. Recurrence 28.7% 6.1% After...
The peritoneum is the second most common site of recurrence in colorectal cancer. Early detection peritoneal carcinomatosis (PC) by imaging difficult. Patients eventually presenting with clinically apparent PC have a poor prognosis. Median survival only about five months if untreated and benefit palliative systemic chemotherapy limited. Only quarter patients are eligible for curative treatment, consisting cytoreductive surgery hyperthermic intraperitoneal (CR/HIPEC). However, effectiveness...
Abstract Background Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in Netherlands. This study investigates whether addition of perioperative systemic therapy to CRS-HIPEC improves oncological outcomes. Methods open-label, parallel-group, phase II-III, randomised, superiority performed nine Dutch tertiary referral centres. Eligible patients are adults who have a good performance status,...
To determine the effect of biological mesh closure on perineal wound healing after extralevator abdominoperineal resection (eAPR).Perineal complications frequently occur eAPR with preoperative radiotherapy for rectal cancer. Cohort studies have suggested that pelvic floor improves healing.Patients were randomly assigned to primary (standard arm) or (intervention arm). A non-cross-linked porcine acellular dermal was sutured remnants in intervention arm, followed by a layered ischioanal and...
Rectal cancer surgery is accompanied with high morbidity and poor long term functional outcome. Screening programs have shown a shift towards more early staged cancers. Patients rectal can potentially benefit significantly from preserving therapy. For the earliest stage cancers, local excision sufficient when risk of lymph node disease subsequent recurrence below 5 %. However, majority cancers are associated an intermediate involvement (5-20 %) suggesting that alone not sufficient, while...
Abstract Background In rectal cancer, watch and wait for patients with a cCR after neoadjuvant treatment has an established evidence base. However, there is lack of consensus on the definition management near-cCR. This study aimed to compare outcomes in who achieved at first reassessment versus later reassessment. Methods registry included from International Watch & Wait Database. Patients were categorized as having or (that near-cCR reassessment) based MRI endoscopy. Organ preservation,...
Portal vein thrombosis is a rare but potentially fatal complication of splenectomy. The aim this study was to assess the incidence, risk factors, treatment and outcome portal after splenectomy in large series patients.All patients who had undergone University Hospital, Rotterdam, between 1984 1997 were reviewed retrospectively. Splenectomy that followed by symptomatic selected for analysis. Risk factors sought.Of 563 splenectomies, nine (2 per cent) complicated thrombosis. All these either...
The choice of incision for laparotomy depends on the area that needs to be exposed, elective or emergency nature operation and personal preference. Type may however have its influence occurrence postoperative wound complications. Techniques features various incisions are discussed, as well incidence their complications.A medline search was conducted identifying prospective randomised trials, retrospective studies with sufficient follow-up, comparing midline, paramedian, transverse oblique...
Because there is no survival benefit of amputation for extremity soft tissue sarcomas (STSs), limb-sparing surgery has become the gold standard. Tumor size reduction by induction therapy to render nonresectable tumors resectable or facilitate function-preserving can be achieved tumor necrosis factor α (TNF) -based and melphalan-based isolated limb perfusion (TM-ILP). This study reports long-term results 231 TM-ILPs locally advanced STS.We analyzed in 208 consecutive patients (1991 2005), who...
BackgroundPelvic exenteration for locally advanced rectal cancer (LARC) and recurrent (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes over time.
<h3>Importance</h3> To date, no randomized clinical trials have investigated perioperative systemic therapy relative to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) alone for resectable colorectal peritoneal metastases (CPM). <h3>Objective</h3> assess the feasibility safety of in patients with CPM response neoadjuvant treatment. <h3>Design, Setting, Participants</h3> An open-label, parallel-group phase 2 trial all 9 Dutch tertiary centers surgical treatment...