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Dirkje W. Sommeijer

ORCID: 0000-0001-7974-5045
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A5002130583
Research Areas
  • Cancer survivorship and care
  • Colorectal Cancer Treatments and Studies
  • Palliative Care and End-of-Life Issues
  • Childhood Cancer Survivors' Quality of Life
  • Genetic factors in colorectal cancer
  • Patient-Provider Communication in Healthcare
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer Genomics and Diagnostics
  • Gastric Cancer Management and Outcomes
  • Nutrition and Health in Aging
  • Cancer Treatment and Pharmacology
  • Intraperitoneal and Appendiceal Malignancies
  • Colorectal Cancer Surgical Treatments
  • Patient Dignity and Privacy
  • Family Support in Illness
  • Pancreatic and Hepatic Oncology Research
  • Radiomics and Machine Learning in Medical Imaging
  • Ovarian cancer diagnosis and treatment
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Blood Coagulation and Thrombosis Mechanisms
  • Colorectal Cancer Screening and Detection
  • Venous Thromboembolism Diagnosis and Management
  • Olfactory and Sensory Function Studies
  • Cancer Risks and Factors
  • Cancer-related cognitive impairment studies

Flevoziekenhuis
 2017-2025

Cancer Center Amsterdam
 2022-2025

Amsterdam University Medical Centers
 2018-2024

University of Amsterdam
 1999-2023

Vrije Universiteit Amsterdam
 2022

Amsterdam UMC Location University of Amsterdam
 1999-2022

De Kinderkliniek
 2017-2022

The University of Sydney
 2013-2019

National Health and Medical Research Council
 2013-2014

Australia New Zealand Gynaecological Oncology Group
 2013

 Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial
OPENALEX - Publications 
Charlotte E.L. Klaver D D Wisselink Cornelis J.A. Punt Pétur Snæbjörnsson Johannes Crezee and 84 more Arend G. J. Aalbers Alexandra Brandt André J. A. Bremers Jacobus W. A. Burger Hans F. J. Fabry F. Ferenschild Sebastiaan Festen Wilhelmina M. U. van Grevenstein Patrick Hemmer Ignace H. J. T. de Hingh Niels F.M. Kok Gijsbert D. Musters Lotte Schoonderwoerd Jurriaan B. Tuynman Anthony W. H. van de Ven Henderik L. van Westreenen Marinus J. Wiezer D. D. E. Zimmerman Annette A. van Zweeden Marcel G. W. Dijkgraaf Pieter J. Tanis Caroline S. Andeweg Vivian P. Bastiaenen Willem A. Bemelman Jarmila D.W. van der Bilt Johanne G. Bloemen Frank C. den Boer Djamila Boerma Daan ten Bokkel Huinink Walter J.A. Brokelman Huib A. Cense Esther C. J. Consten Geert‐Jan Creemers Rogier M. P. H. Crolla Jan‐Willem T. Dekker Jennifer Demelinne Marc J. van Det Karin K. van Diepen Marjolein Diepeveen Eino B. van Duyn Esther D. van den Ende Pauline Evers Anna A. W. van Geloven Erwin van der Harst Jeroen Heemskerk Joost T. Heikens Daniël A. Hess Bas Inberg Jan B.�M.�J. Jansen Frank W.H. Kloppenberg Thomas J.M. Kootstra R.T.J. Kortekaas Maartje Los Eva V. E. Madsen H.C.J. van der Mijle Linda Mol Peter A. Neijenhuis Simon W. Nienhuijs Loes van den Nieuwenhof Koen Peeters Sebastiaan W. Polle Jolien Pon Pieter Poortman Sandra A. Radema Bert van Ramshorst Philip R. de Reuver Koen P. Rovers Roderick F. Schmitz Nina R. Sluiter Dirkje W. Sommeijer D.J.A. Sonneveld T.C. van Sprundel Sanne C. Veltkamp Maarten Vermaas Victor J. Verwaal Emma C. E. Wassenaar Johannes A. Wegdam Johannes H.W. de Wilt Marinke Westerterp Fennie Wit Arjen J. Witkamp Karlijn Woensdregt Edwin S. van der Zaag Mandy Zournas

10.1016/s2468-1253(19)30239-0 article EN ˜The œLancet. Gastroenterology & hepatology 2019-07-29
 Role of eHealth application Oncokompas in supporting self-management of symptoms and health-related quality of life in cancer survivors: a randomised, controlled trial
OPENALEX - Publications 
Anja van der Hout Cornelia F. van Uden‐Kraan Karen Holtmaat Femke Jansen Birgit I. Lissenberg‐Witte and 24 more Grard A. P. Nieuwenhuijzen José A. Hardillo Robert J. Baatenburg de Jong N. L. Tiren-Verbeet Dirkje W. Sommeijer Koen de Heer C. G. Schaar Robert-Jan E Sedee K. Bosscha Michiel W. M. van den Brekel Japke F. Petersen Matthijs Westerman Jimmie Honings Robert P. Takes Ilse Houtenbos W.T. van den Broek Remco de Bree P. Jansen Simone E. J. Eerenstein C. René Leemans Josée M. Zijlstra Pim Cuijpers Lonneke V. van de Poll‐Franse Irma M. Verdonck‐de Leeuw

10.1016/s1470-2045(19)30675-8 article EN The Lancet Oncology 2019-12-12
 Extended adjuvant aromatase inhibition after sequential endocrine therapy (DATA): a randomised, phase 3 trial
OPENALEX - Publications 
Vivianne C. G. Tjan‐Heijnen Irene E.G. van Hellemond Petronella G.M. Peer Astrid C.P. Swinkels Carolien H. Smorenburg and 80 more Maurice J.C. van der Sangen Judith R. Kroep Hiltje de Graaf Aafke H. Honkoop Frans Erdkamp Franchette W.P.J. van den Berkmortel Maaike de Boer W Roos Sabine C. Linn Alexander L.T. Imholz Caroline Seynaeve Jos Kitzen L.J.A. Strobbe E.A. Kouwenhoven T van Dalen Adriaan J van Overbeeke J. K. S. Nuytinck I.E. Arntz R.J.B. Blaisse Hein B.A.C. Stockmann P.H.A. Nijhuis Gerrit-Jan Veldhuis W.J.B. Mastboom J.M.G.H. van Riel Johan Hygum Dam Marien O. den Boer Mariëtte J Agterof Marnix A.J. de Roos Rudi M. H. Roumen Jacobus J. M. van der Hoeven Aart Beeker Ron Koelemij Aart van Bochove G. S. Madretsma Ester Siemerink Onno R. Guicherit Allert H. Vos Grard A. P. Nieuwenhuijzen Diederik F.S. Kehrer F.A.A. Valster Bea C. Tanis Theo van Voorthuizen Ankie M.T. van der Velden R.A. Hellingman R. Vree Q. van Rossum-Schornagel Jetske M. Meerum Terwogt Willemien G. van Leeuwen-Breuk Janny G. Haasjes Marjan A. Davidis-van Schoonhoven Eline Vriens M. Jagers E.W. Muller P.P. Schiphorst C.J. van Groeningen M.A. van Dijk Esmée J. van Vliet Eva Schepers J. W. S. Merkus Nico G. J. van Diemen R.C. van Doorn K. Bosscha R. Den Toom P.C. van der Velden C.T.A.M. van Rossum Hendrika M. Oosterkamp Richard van Hillegersberg B. Jas E.E.M. Weernink J. M. A. Ketel JP Jansen John K. Maring Marc J. P. M. Govaert Yvonne Kamm M M Vleugel Sjoerd Hovenga J. de Boer H. Potthoff Dirkje W. Sommeijer Eric J. van Dulken

10.1016/s1470-2045(17)30600-9 article EN The Lancet Oncology 2017-10-13
 Differences in dietary intake during chemotherapy in breast cancer patients compared to women without cancer
OPENALEX - Publications 
Y. C. de Vries M. M. G. A. van den Berg J.H.M. de Vries Sanne Boesveldt J. Th. C. M. de Kruif and 9 more N. Buist A. Haringhuizen Maartje Los Dirkje W. Sommeijer J. H. N. Timmer-Bonte Hanneke W.M. van Laarhoven Marjolein Visser Ellen Kampman Renate M. Winkels

Breast cancer patients receiving chemotherapy often experience symptoms such as nausea, vomiting and loss of appetite that potentially affect dietary habits. This study assessed the intake energy, macronutrients food groups before during in breast compared with women without cancer, determined association between energy macronutrient intake. included 117 newly diagnosed scheduled for 88 cancer. Habitual was a frequency questionnaire. Two 24-h recalls were completed on random days each...

10.1007/s00520-017-3668-x article EN cc-by-nc Supportive Care in Cancer 2017-03-16
 Effect of physical exercise on cognitive function after chemotherapy in patients with breast cancer: a randomized controlled trial (PAM study)
OPENALEX - Publications 
Emmie W. Koevoets Sanne B. Schagen Michiel B. de Ruiter Mirjam I. Geerlings Lenja Witlox and 25 more Elsken van der Wall Martijn M. Stuiver Gabe S. Sonke Miranda J. Velthuis Jan J. Jobsen Marian B. E. Menke‐Pluijmers Emine Göker Carmen C. van der Pol Monique E.M.M. Bos Lidwine W. Tick Nel A. van Holsteijn Job van der Palen Anne M. May Evelyn M. Monninkhof A. Haringhuizen Wim A. van der Steeg Dirkje W. Sommeijer Frederiek Terheggen C.F.J.M. Blanken-Peeters Harold Fliervoet Margrethe Schlooz-Vries Tanja G. Frakking Marc W. A. van Tilburg Corina Oldenhuis Maartje F. Sier

Abstract Background Up to 60% of breast cancer patients treated with chemotherapy is confronted cognitive problems, which can have a significant impact on daily activities and quality life (QoL). We investigated whether exercise training improves cognition in chemotherapy-exposed 2–4 years after diagnosis. Methods Chemotherapy-exposed patients, both self-reported problems lower than expected performance neuropsychological tests, were randomized an or control group. The 6-month intervention...

10.1186/s13058-022-01530-2 article EN cc-by Breast Cancer Research 2022-05-26
 Trajectories of health‐related quality of life and symptom burden in patients with advanced cancer towards the end of life: Longitudinal results from the eQuiPe study
OPENALEX - Publications 
Moyke A. J. Versluis Natasja Raijmakers Arnold Baars M.H.J. van den Beuken-van Everdingen Alexander de Graeff and 8 more Mathijs P. Hendriks Wouter K. de Jong Jeroen S. Kloover Evelien Kuip Caroline Mandigers Dirkje W. Sommeijer Yvette M. van der Linden Lonneke V. van de Poll‐Franse

The number of individuals with advanced cancer is increasing, making palliative care more important. However, there limited knowledge in the Netherlands about quality received by patients phase. This why comprehensive organization (IKNL) started 'eQuiPe study' to understand experienced and life their relatives further improve care. Patients (stage IV) were asked complete questionnaires regarding every three months 40 Dutch hospitals. (n=1108) declines, particularly last life, accompanied an...

10.1002/cncr.35060 article EN Cancer 2023-10-13
 Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: a longitudinal analysis
OPENALEX - Publications 
Evertine Wesselink Hendriek C. Boshuizen Anne‐Sophie van Lanen Dieuwertje E. Kok Jeroen W. G. Derksen and 12 more Karel C Smit Johannes H.W. de Wilt Miriam Koopman Anne M. May Ellen Kampman Fränzel J.B. van Duijnhoven Henk K. van Halteren Jan Willem T. Dekker Dirkje W. Sommeijer D J A Sonneveld Frederiek Terheggen Mark P.S. Sie

The aim of this study was to longitudinally investigate dietary and lifestyle inflammation scores their interaction in relation risk colorectal cancer (CRC) recurrence all-cause mortality.

10.1016/j.clnu.2024.07.028 article EN cc-by-nc-nd Clinical Nutrition 2024-07-27
 Taste and smell perception and quality of life during and after systemic therapy for breast cancer
OPENALEX - Publications 
Y. C. de Vries Sanne Boesveldt Celine S. Kelfkens E. E. Posthuma M. M. G. A. van den Berg and 9 more J. Th. C. M. de Kruif A. Haringhuizen Dirkje W. Sommeijer N. Buist S. Grosfeld Cees de Graaf Hanneke W.M. van Laarhoven Ellen Kampman Renate M. Winkels

The purpose of the study was to assess self-reported taste and smell perception after chemotherapy in breast cancer patients compared with women without cancer, whether is associated quality life end chemotherapy. We included 135 newly diagnosed who completed 114 cancer. Questionnaires on taste, smell, were shortly 6 months (patients) or at two moments months' time window between (comparisons). Self-reported significantly lower comparison group. Most recovered chemotherapy, although still...

10.1007/s10549-018-4720-3 article EN cc-by Breast Cancer Research and Treatment 2018-02-23
 Nationwide comprehensive gastro-intestinal cancer cohorts: the 3P initiative
OPENALEX - Publications 
Robert R.J. Coebergh van den Braak L. Bengt van Rijssen Jessy Joy van Kleef Geraldine R. Vink Maaike Berbée and 54 more Mark I. van Berge Henegouwen Haiko J. Bloemendal Marco J. Bruno Mark C. Burgmans Olivier R. Busch P. P. L. O. Coene Veerle M.H. Coupé Jan Willem T. Dekker Casper H.J. van Eijck Marloes A.G. Elferink Frans Erdkamp Wilhelmina M. U. van Grevenstein Jan Willem B. de Groot Nicole C.T. van Grieken Ignace H. J. T. de Hingh Maarten C.C.M. Hulshof Jan N.M. IJzermans Linda Kwakkenbos V.E.P.P. Lemmens Maartje Los Gerrit A. Meijer I. Quintus Molenaar Grard A. P. Nieuwenhuijzen Mirre E. de Noo Lonneke V. van de Poll‐Franse Cornelis J.A. Punt R. C. Rietbroek Wilfried Roeloffzen Tom Rozema Jelle P. Ruurda Johanna W. van Sandick A. H. W. Schiphorst Harvey Schipper Peter D. Siersema Marije Slingerland Dirkje W. Sommeijer Manon C.W. Spaander Mirjam A. G. Sprangers Hein B.A.C. Stockmann Marin Strijker Geertjan van Tienhoven Liesbeth Timmermans Manuel L. R. Tjin‐A‐Ton Ankie M.T. van der Velden Marlies Verhaar Helena M. Verkooijen Wouter J. Vles Judith de Vos‐Geelen Johanna W. Wilmink D. D. E. Zimmerman Martijn G.H. van Oijen Miriam Koopman Marc G. Besselink Hanneke W.M. van Laarhoven

Background: The increasing sub-classification of cancer patients due to more detailed molecular classification tumors, and limitations current trial designs, require innovative research designs. We present the design, governance standing three comprehensive nationwide cohorts including pancreatic, esophageal/gastric, colorectal (NCT02070146). Multidisciplinary collection clinical data, tumor tissue, blood samples, patient-reported outcome (PRO) measures with a coverage, provides...

10.1080/0284186x.2017.1346381 article EN cc-by-nc-nd Acta Oncologica 2017-07-19
 Effect of a Skills Training for Oncologists and a Patient Communication Aid on Shared Decision Making About Palliative Systemic Treatment: A Randomized Clinical Trial
OPENALEX - Publications 
Inge Henselmans Hanneke W.M. van Laarhoven Pomme E. A. van Maarschalkerweerd Hanneke C.J.M. de Haes Marcel G. W. Dijkgraaf and 7 more Dirkje W. Sommeijer Petronella B. Ottevanger Helle‐Brit Fiebrich Serge E. Dohmen Geert-Jan Creemers Filip De Vos Ellen M.A. Smets

Abstract Background Palliative systematic treatment offers uncertain and often limited benefits, the burden can be high. Hence, decisions require shared decision making (SDM). This trial examined independent combined effect of an oncologist training a patient communication aid on SDM. Methods In this multicenter randomized controlled with four parallel arms (2016–2018), oncologists (n = 31) were to receive SDM skills or not. The consisted reader, two group sessions, booster session,...

10.1634/theoncologist.2019-0453 article EN cc-by-nc-nd The Oncologist 2019-11-26
 Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment
OPENALEX - Publications 
Dave E. W. van der Kruijssen Sjoerd G. Elias Geraldine R. Vink Karlijn L. van Rooijen Jorine ‘t Lam-Boer and 88 more Linda Mol Cornelis J.A. Punt Johannes H.W. de Wilt Miriam Koopman Gijs J.D. van Acker Rahim Altaf Kees van Arkel Coen I.M. Baeten Sandra D. Bakker Frank C. den Boer Marien O. den Boer K. Bosscha Edwin A. van Breugel Rebecca P. M. Brosens Huib A. Cense Esther C. J. Consten Geert‐Jan Creemers Hester van Cruijsen Wendy M. van der Deure Joyce M. van Dodewaard Anne-Lene G. Fromm A. J. Gelderblom Michael F. Gerhards Marie-José de Gier Eelco J. R. de Graaf Wilhelmina M. U. van Grevenstein Jan Willem B. de Groot Brigitte C.M. Haberkorn Jamal Oulad Hadj Paul Hamberg Erwin van der Harst Helgi H. Helgason Mathijs P. Hendriks Daniël A. Hess Ignace H. J. T. de Hingh Ronald Hoekstra Joost A.B. van der Hoeven M.J. van Hoogstraten Henrik Jakobsen Felix E. de Jongh Emile D. Kerver Monica L Kjaer Bart C. Kuenen Philomeen Kuijer Sophie A. Kurk Wouter K. G. Leclercq Lobke L. van Leeuwen-Snoeks Jeroen W. A. Leijtens Gábor Liposits O. J. L. Loosveld Martijn F. Lutke Holzik Peter Nieboer Jesper Dan Nielsen Koen Peeters Lone N. Petersen Apollo Pronk Bareld B. Pultrum Koen Reijnders J.M.G.H. van Riel Ron C. Rietbroek George P. van der Schelling Wilhelmina H. Schreurs Nis H. Schlesinger Heidi Schut Michael Seiersen Lieke H. J. Simkens Dirkje W. Sommeijer Pieter J. Tanis Mehmet Temizkan Marc W. A. van Tilburg Marija Trajkovic Anthony W. H. van de Ven Henk M.W. Verheul Mareille Verseveld Jeroen Vincent Wouter J. Vles F. Jeroen Vogelaar Aad I. de Vos Allert H. Vos Ronald J.C.L.M. Vuylsteke Wim Bleeker Dareczka Wasowicz-Kemps Johannes A. Wegdam Henderik L. van Westreenen Louise M. de Widt-Levert Agnès J. van de Wouw Mette Yilmaz Peter van Duijvendijk

<h3>Importance</h3> The role of primary tumor resection (PTR) in synchronous patients with metastatic colorectal cancer (mCRC) who had unresectable metastases and few or absent symptoms their is unclear. Studying subgroups low postoperative mortality may identify potentially benefit from PTR. <h3>Objective</h3> To determine the difference 60-day between randomized to systemic treatment only vs PTR followed by treatment, explore risk factors associated mortality. <h3>Design, Setting,...

10.1001/jamasurg.2021.4992 article EN JAMA Surgery 2021-10-09
 Self-care, resilience, and caregiver burden in relatives of patients with advanced cancer: results from the eQuiPe study
OPENALEX - Publications 
Janneke van Roij Linda Brom Dirkje W. Sommeijer Lonneke V. van de Poll‐Franse Natasja Raijmakers

Abstract Purpose Relatives are often involved in caregiving for patients with advanced cancer and carry a heavy burden. Self-care resilience might be beneficial to enhance their wellbeing burden-bearing capacity. This study assessed the engagement self-care relatives of its association caregiver Methods analyzed baseline data eQuiPe study, prospective longitudinal, multicenter, observational on quality care life which (Self-care Practices Scale), (Connor-Davidson Resilience burden (Zarit...

10.1007/s00520-021-06365-9 article EN cc-by Supportive Care in Cancer 2021-07-03
 Upfront resection versus no resection of the primary tumor in patients with synchronous metastatic colorectal cancer: the randomized phase III CAIRO4 study conducted by the Dutch Colorectal Cancer Group and the Danish Colorectal Cancer Group
OPENALEX - Publications 
Dave E. W. van der Kruijssen Sjoerd G. Elias Peter M. van de Ven Karlijn L. van Rooijen Jorine ‘t Lam-Boer and 88 more Linda Mol Cornelis J.A. Punt Dirkje W. Sommeijer Pieter J. Tanis Jørn Dalsgaard Nielsen M.K. Yilmaz J.M.G.H. van Riel D.K. Wasowiz-Kemps O. J. L. Loosveld George P. van der Schelling J.W.B. de Groot Henderik L. van Westreenen Henrik Jakobsen A.L. Fromm Paul Hamberg M. Verseveld Claudia Jaensch Gábor Liposits Peter van Duijvendijk Jamal Oulad Hadj Joost A.B. van der Hoeven Marija Trajkovic Johannes H.W. de Wilt M. Koopman Jeroen Vincent Johannes A. Wegdam Brigitte C.M. Haberkorn Erwin van der Harst Mathijs P. Hendriks Wilhelmina H. Schreurs Huib A. Cense Ron C. Rietbroek Marie-José de Gier Edwin A. van Breugel Aad I. de Vos Rebecca P. M. Brosens Pascal G. Doornebosch Felix E. de Jongh Wouter J. Vles Marien O. den Boer Jeroen W. A. Leijtens A. J. Gelderblom Koen Peeters Bart C. Kuenen Bareld B. Pultrum Joyce M. van Dodewaard-de Jong Esther C. J. Consten A.J. Yes van de Wouw Joop Konsten Ronald Hoekstra Martijn F. Lutke Holzik Allert H. Vos M.J. van Hoogstraten Nis H. Schlesinger Geert-Jan Creemers Ignace H. J. T. de Hingh Monica L Kjaer Lone N. Petersen Michael Seiersen Rahim Altaf Hester van Cruijsen Daniël A. Hess Lobke L. van Leeuwen-Snoeks Apollo Pronk Coen I.M. Baeten Wendy M. van der Deure K. Bosscha Heidi Schut Wouter K. G. Leclercq Lieke H. J. Simkens Koen Reijnders Kees van Arkel W.M.U. Helma van Grevenstein Anthony W. H. van de Ven Ronald J.C.L.M. Vuylsteke Philomeen Kuijer Sandra D. Bakker Hauwy Goei Helgi H. Helgason Gijs J.D. van Acker Mehmet Temizkan Marc W. A. van Tilburg Michael F. Gerhards Emile D. Kerver Elske C. Gootjes Peter Nieboer Wim Bleeker Gitta Bleeker

Upfront primary tumor resection (PTR) has been associated with longer overall survival (OS) in patients synchronous unresectable metastatic colorectal cancer (mCRC) retrospective analyses. The aim of the CAIRO4 study was to investigate whether addition upfront PTR systemic therapy resulted a benefit mCRC without severe symptoms their tumor.

10.1016/j.annonc.2024.06.001 article EN cc-by Annals of Oncology 2024-06-07
 Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study
OPENALEX - Publications 
Suzanna J. Schraa Karlijn L. van Rooijen Dave E. W. van der Kruijssen Carmen Rubio‐Alarcón Jillian Phallen and 51 more Mark Sausen John K. Simmons Veerle M.H. Coupé Wilhelmina M. U. van Grevenstein Sjoerd G. Elias Helena M. Verkooijen Miangela M. Laclé Linda J.W. Bosch Daan van den Broek Gerrit A. Meijer Victor E. Velculescu Remond J.A. Fijneman Geraldine R. Vink Miriam Koopman Mich S. Dunker Martijn F. Lutke Holzik Ronald Hoekstra Dirkje W. Sommeijer Jarmila D.W. van der Bilt Esther C. J. Consten Geert A. Cirkel Thijs A. Burghgraef Emma M. van der Schans Peter Nieboer Ron C. Rietbroek Jan Willem T. Dekker Arie J. Verschoor Koen Talsma Rebecca P. M. Brosens Helgi H. Helgason Andreas Marinelli Ignace H. J. T. de Hingh Corina N.A.M. Oldenhuis Jan B.�M.�J. Jansen Henk K. van Halteren Hein B.A.C. Stockmann Aart Beeker K. Bosscha Hans Pruijt Leontine E.A.M.M. Spierings Liselot Valkenburg‐van Iersel Wouter J. Vles Felix E. de Jongh Hester van Cruijsen Joost T. Heikens D. D. E. Zimmerman R J van Alphen A. H. W. Schiphorst Lobke L. van Leeuwen-Snoeks Jeroen Vogelaar Natascha A. J. B. Peters

Abstract Background Accurate detection of patients with minimal residual disease (MRD) after surgery for stage II colon cancer (CC) remains an urgent unmet clinical need to improve selection who might benefit form adjuvant chemotherapy (ACT). Presence circulating tumor DNA (ctDNA) is indicative MRD and has high predictive value recurrent disease. The MEDOCC-CrEATE trial investigates how many CC detectable ctDNA will accept ACT whether reduces the risk recurrence in these patients....

10.1186/s12885-020-07252-y article EN cc-by BMC Cancer 2020-08-20
 The eHealth self-management application ‘Oncokompas’ that supports cancer survivors to improve health-related quality of life and reduce symptoms: which groups benefit most?
OPENALEX - Publications 
Anja van der Hout Karen Holtmaat Femke Jansen Birgit I. Lissenberg‐Witte Cornelia F. van Uden‐Kraan and 24 more Grard A. P. Nieuwenhuijzen José A. Hardillo Robert J. Baatenburg de Jong N. L. Tiren-Verbeet Dirkje W. Sommeijer Koen de Heer C. G. Schaar Robert-Jan Sedee K. Bosscha Michiel W. M. van den Brekel Japke F. Petersen Matthijs Westerman Jimmie Honings Robert P. Takes Ilse Houtenbos W.T. van den Broek Remco de Bree P. Jansen Simone E. J. Eerenstein C. René Leemans Josée M. Zijlstra Pim Cuijpers Lonneke V. van de Poll‐Franse Irma M. Verdonck‐de Leeuw

Background Oncokompas is a web-based self-management application that supports cancer survivors to monitor their health-related quality of life (HRQOL) and symptoms, obtain personalised feedback tailored options for supportive care. In large randomised controlled trial among head neck cancer, colorectal breast (non-)Hodgkin lymphoma, proved improve HRQOL, reduce several tumour-specific symptoms. Effect sizes were however small, no effect was observed on the primary outcome patient...

10.1080/0284186x.2020.1851764 article EN cc-by-nc-nd Acta Oncologica 2020-12-21
 Trajectories of health-related quality of life and psychological distress in patients with colorectal cancer: A population-based study
OPENALEX - Publications 
Seyed M. Qaderi J. Van Der Heijden Rob H.A. Verhoeven Johannes H.W. de Wilt José A. E. Custers and 52 more Geerard L. Beets Eric J.T. Belt Maaike Berbée Frédérique H. Beverdam Ruud Blankenburgh Peter Paul L. O. Coene Jan Willem B. de Groot Ignace H. J. T. de Hingh Aad I. de Vos Johannes H.W. de Wilt Jan Willem T. Dekker Frans Erdkamp A. Haringhuizen Helgi H. Helgason Mathijs P. Hendriks Ronald Hoekstra Jan N.M. IJzermans Jan B.�M.�J. Jansen Frank W.H. Kloppenberg Maartje Los Martijn R. Meijerink Leonie J. Mekenkamp Peter Nieboer Koen Peeters Natascha A. J. B. Peters Marco B. Polée Hans Pruijt Patricia Quarles van Ufford-Mannesse Ron C. Rietbroek A. H. W. Schiphorst Arjan Schouten van der Velden Ruud W.M. Schrauwen Mark P.S. Sie Lieke H. J. Simkens Dirkje W. Sommeijer D J A Sonneveld Leontine E.A.M.M. Spierings Hein B.A.C. Stockmann Koen Talsma Albert J. ten Tije Frederiek Terheggen Manuel L. R. Tjin‐A‐Ton Liselot Valkenburg‐van Iersel Hester van Cruijsen Ankie M.T. van der Velden Joyce M. van Dodewaard-de Jong Anja U.G. van Lent Theo van Voorthuizen Maarten Vermaas Wouter J. Vles Jeroen Vogelaar D. D. E. Zimmerman

BackgroundThe aim of this nationwide cohort study was to examine the course symptoms and trajectories health-related quality life (HR-QoL) psychological distress during follow-up identify vulnerable patients.MethodsPatients with pathological stage I–III colorectal cancer (CRC) between 2013 2018 were included. Baseline characteristics collected from Netherlands Cancer Registry, patients completed European Organisation for Research Treatment QLQ-C30/CR29, Hospital Anxiety Depression Scale low...

10.1016/j.ejca.2021.08.050 article EN cc-by European Journal of Cancer 2021-10-19
 Adjuvant Hyperthermic Intraperitoneal Chemotherapy in Patients With Locally Advanced Colon Cancer (COLOPEC): 5-Year Results of a Randomized Multicenter Trial
OPENALEX - Publications 
Emma S. Zwanenburg Charlotte E.L. Klaver D D Wisselink Cornelis J.A. Punt Pétur Snæbjörnsson and 86 more Johannes Crezee Arend G. J. Aalbers Alexandra R. M. Brandt‐Kerkhof André J. A. Bremers Pim J. W. A. Burger Hans F. J. Fabry F. Ferenschild Sebastiaan Festen Wilhemina M.U. van Grevenstein Patrick Hemmer Ignace H. J. T. de Hingh Niels F.M. Kok Miranda Kusters G.D. Musters Lotte Schoonderwoerd Jurriaan B. Tuynman Anthony W. H. van de Ven Henderik L. van Westreenen Marinus J. Wiezer D. D. E. Zimmerman Annette van Zweeden Marcel G. W. Dijkgraaf Pieter J. Tanis Caroline S. Andeweg Vivian P. Bastiaenen Willem A. Bemelman Jarmila D.W. van der Bilt Johanne G. Bloemen Frank C. den Boer Djamila Boerma Daan ten Bokkel Huinink Walter J.A. Brokelman Huib A. Cense Esther C. J. Consten Geert-Jan Creemers Rogier M. P. H. Crolla Jan‐Willem T. Dekker Jennifer Demelinne Marc J. van Det Karin K. van Diepen Marjolein Diepeveen Eino B. van Duyn Esther D. van den Ende Pauline Evers Anna A. W. van Geloven Erwin van der Harst Jeroen Heemskerk Joost T. Heikens Daniël A. Hess Bas Inberg Jan B.�M.�J. Jansen Frank W.H. Kloppenberg Thomas J.M. Kootstra R.T.J. Kortekaas Maartje Los Eva V. E. Madsen H.C.J. van der Mijle Linda Mol Peter A. Neijenhuis Simon W. Nienhuijs Loes van den Nieuwenhof Koen Peeters Sebastiaan W. Polle Jolien Pon Pieter Poortman Sandra A. Radema Bert van Ramshorst Philip R. de Reuver Koen P. Rovers Roderick F. Schmitz Nina R. Sluiter Dirkje W. Sommeijer Eric Sonneveld T.C. van Sprundel Sanne C. Veltkamp Maarten Vermaas Victor J. Verwaal Emma C. E. Wassenaar Johannes A. Wegdam Johannes H.W. de Wilt Marinke Westerterp Fennie Wit Arjen J. Witkamp Karlijn Woensdregt Edwin S. van der Zaag Mandy Zournas

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary point, may be published when key planned co-primary or secondary analyses are not yet available. Trial Updates provide an opportunity to disseminate additional results from studies, in JCO elsewhere, for which point has already been reported. Whether adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) might prevent peritoneal metastases after...

10.1200/jco.22.02644 article EN Journal of Clinical Oncology 2023-11-03
 Physical symptoms, coping styles and quality of life in recurrent ovarian cancer: A prospective population-based study over the last year of life
OPENALEX - Publications 
M Price Melanie L. Bell Dirkje W. Sommeijer Michael Friedlander Martin R. Stockler and 3 more Anna deFazio Penelope M. Webb Phyllis Butow

10.1016/j.ygyno.2013.03.031 article EN Gynecologic Oncology 2013-04-08
 Altered food preferences and chemosensory perception during chemotherapy in breast cancer patients: A longitudinal comparison with healthy controls
OPENALEX - Publications 
Y. C. de Vries Renate M. Winkels M. M. G. A. van den Berg Cees de Graaf Celine S. Kelfkens and 7 more J. Th. C. M. de Kruif Emine Göker S. Grosfeld Dirkje W. Sommeijer Hanneke W.M. van Laarhoven Ellen Kampman Sanne Boesveldt

10.1016/j.foodqual.2017.09.003 article EN Food Quality and Preference 2017-09-07
 Training for Medical Oncologists on Shared Decision-Making About Palliative Chemotherapy: A Randomized Controlled Trial
OPENALEX - Publications 
Inge Henselmans Hanneke W.M. van Laarhoven Hanneke C.J.M. de Haes Meltem Tokat Ellen G. Engelhardt and 8 more Pomme E. A. van Maarschalkerweerd Marleen Kunneman Petronella B. Ottevanger Serge E. Dohmen Geert-Jan Creemers Dirkje W. Sommeijer Filip De Vos Ellen M.A. Smets

Abstract Background Systemic treatment for advanced cancer offers uncertain and sometimes limited benefit, while the burden can be high. This study examines effect of shared decision-making (SDM) training medical oncologists on observed SDM in standardized patient assessments. Materials Methods A randomized controlled trial comparing with standard practice was conducted. Medical oncologists-in-training (n = 31) participated a video-recorded, assessment at baseline (T0) after 4 months (T1,...

10.1634/theoncologist.2018-0090 article EN The Oncologist 2018-06-29
 Body composition is associated with risk of toxicity-induced modifications of treatment in women with stage I–IIIB breast cancer receiving chemotherapy
OPENALEX - Publications 
M. M. G. A. van den Berg Dieuwertje E. Kok Liesbeth Posthuma Lisette Kamps Celine S. Kelfkens and 12 more N. Buist Maud M. Geenen A. Haringhuizen Joan B. Heijns Rianne H. M. A. van Lieshout Maartje Los Dirkje W. Sommeijer Johanna N.H. Timmer-Bonte Anja Th. C. M. de Kruif Hanneke W.M. van Laarhoven Ellen Kampman Renate M. Winkels

Initial dose of chemotherapy is planned based on body surface area, which does not take composition into account. We studied the association between fat mass (kg and relative to total weight) as well lean toxicity-induced modifications treatment in breast cancer patients receiving chemotherapy. In an observational study among 172 (stage I–IIIB) Netherlands, we assessed using dual-energy X-ray scans. Information treatment, defined reductions, cycle delays, regimen switches, or premature...

10.1007/s10549-018-5014-5 article EN cc-by Breast Cancer Research and Treatment 2018-10-23
 OVQUEST – Life after the diagnosis and treatment of ovarian cancer - An international survey of symptoms and concerns in ovarian cancer survivors
OPENALEX - Publications 
Kate Webber Elisa Carolus Linda Mileshkin Dirkje W. Sommeijer Jessica N. McAlpine and 7 more Sarah Bladgen Robert L. Coleman Thomas J. Herzog Jalid Sehouli Sara Nasser Guelhan Inci Michael Friedlander

10.1016/j.ygyno.2019.08.009 article EN Gynecologic Oncology 2019-08-13
 The Prospective Dutch Colorectal Cancer (PLCRC) cohort: real-world data facilitating research and clinical care
OPENALEX - Publications 
Jeroen W. G. Derksen Geraldine R. Vink Marloes A.G. Elferink Jeanine Roodhart Helena M. Verkooijen and 59 more Wilhelmina M. U. van Grevenstein Peter D. Siersema Anne M. May Miriam Koopman Geerard L. Beets Eric J.T. Belt Maaike Berbée Frédérique H. Beverdam Ruud Blankenburgh Peter Paul L. O. Coene Hester van Cruijsen Jan Willem T. Dekker Joyce M. van Dodewaard-de Jong Frans Erdkamp Jan Willem B. de Groot A. Haringhuizen Helgi H. Helgason Mathijs P. Hendriks Ignace H. J. T. de Hingh Ronald Hoekstra Jan N.M. IJzermans Jan B.�M.�J. Jansen Frank W.H. Kloppenberg Anja U.G. van Lent Maartje Los Martijn R. Meijerink Leonie J. Mekenkamp Peter Nieboer Koen Peeters Natascha A. J. B. Peters Marco B. Polée Hans Pruijt Cornelis J.A. Punt Patricia Quarles van Ufford-Mannesse Ron C. Rietbroek A. H. W. Schiphorst Arjan Schouten van der Velden Ruud W.M. Schrauwen Mark P.S. Sie Lieke H. J. Simkens Dirkje W. Sommeijer D J A Sonneveld Leontine E A M M Spierings Hein B.A.C. Stockmann Koen Talsma Frederiek Terheggen Albert J. ten Tije Manuel L. R. Tjin‐A‐Ton Liselot Valkenburg‐van Iersel Renzo P. Veenstra Ankie M.T. van der Velden Maarten Vermaas Wouter J. Vles Jeroen Vogelaar Theo van Voorthuizen Aad I. de Vos Johannes A. Wegdam Johannes H. W. de Wilt D. D. E. Zimmerman

Real-world data (RWD) sources are important to advance clinical oncology research and evaluate treatments in daily practice. Since 2013, the Prospective Dutch Colorectal Cancer (PLCRC) cohort, linked Netherlands Registry, serves as an infrastructure for scientific collecting additional patient-reported outcomes (PRO) biospecimens. Here we report on cohort developments investigate what extent PLCRC reflects "real-world". Clinical demographic characteristics of participants were compared with...

10.1038/s41598-020-79890-y article EN cc-by Scientific Reports 2021-02-16
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