- Cancer Risks and Factors
- Metabolism, Diabetes, and Cancer
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Colorectal and Anal Carcinomas
- Growth Hormone and Insulin-like Growth Factors
- Nutrition and Health in Aging
- Cancer, Lipids, and Metabolism
- Intraperitoneal and Appendiceal Malignancies
- Genetic factors in colorectal cancer
- Liver Disease Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Appendicitis Diagnosis and Management
- Nutritional Studies and Diet
- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Pituitary Gland Disorders and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Ear and Head Tumors
- Multiple and Secondary Primary Cancers
- Hernia repair and management
- Cancer survivorship and care
The Christie NHS Foundation Trust
2016-2025
University of Manchester
2016-2025
National Health Service
2000-2025
NIHR Manchester Biomedical Research Centre
2017-2025
Champalimaud Foundation
2025
Hospital Alemão Oswaldo Cruz
2025
Beneficência Portuguesa de São Paulo
2025
The Christie Hospital
2012-2024
Cancer Research UK Manchester Institute
2013-2024
Cancer Research UK Manchester Centre
2019-2024
High body-mass index (BMI; defined as 25 kg/m(2) or greater) is associated with increased risk of cancer. To inform public health policy and future research, we estimated the global burden cancer attributable to high BMI in 2012.
<h3>Importance</h3> Intensive follow-up of patients after curative surgery for colorectal cancer is common in clinical practice, but evidence a survival benefit limited. <h3>Objective</h3> To examine overall mortality, cancer–specific and recurrence rates among with stage II or III who were randomized to 2 alternative schedules testing computed tomography carcinoembryonic antigen. <h3>Design, Setting, Participants</h3> Unblinded trial including 2509 treated at 24 centers Sweden, Denmark,...
Excess adiposity is associated with increased risks of developing adult malignancies. To inform public health policy and guide further research, the incident cancer burden attributable to excess body mass index (BMI >or= 25 kg/m(2)) across 30 European countries were estimated. Population (PARs) calculated using European- gender-specific risk estimates from a published meta-analysis mean BMI World Health Organization Global Infobase. Country-specific numbers new cancers derived Globocan2002....
Previous studies have shown that extracapsular dissection (ECD) is an alternative approach to superficial parotidectomy (SP) for pleomorphic adenoma parotid tumours, associated with low recurrence rates equal those following SP, but significantly reduced morbidity. However, if a malignant tumour masquerades as clinically benign lump, this may be inappropriate. This study addressed question by analysing the outcome of 821 consecutive patients tumours treated at one centre over 40 years and...
Abstract Between 1947 and 1992, 1403 patients with 1432 salivary gland tumours were treated at the Christie Hospital, Manchester. There 1194 epithelial neoplasms: parotid, 1082 (91 per cent); submandibular, 47 (4 minor glands, 65 (5 cent). The commonest histological diagnoses pleomorphic adenoma (n = 776) adenolymphoma 159). A total of 244 carcinomas seen (adenoid cystic carcinoma, n 75). Treatment was primarily surgical, conservative where possible, determined by tumour extent not...