Niall Brindl
A5074119494- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatic and Hepatic Oncology Research
- COVID-19 Clinical Research Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Hernia repair and management
- COVID-19 and Mental Health
- Healthcare cost, quality, practices
- Colorectal Cancer Surgical Treatments
- Neuroendocrine Tumor Research Advances
- Diversity and Career in Medicine
- Long-Term Effects of COVID-19
- Surgical Simulation and Training
- Pancreatitis Pathology and Treatment
- Gastrointestinal Tumor Research and Treatment
- Appendicitis Diagnosis and Management
- Aortic aneurysm repair treatments
- Hemodynamic Monitoring and Therapy
- Healthcare Systems and Challenges
- SARS-CoV-2 and COVID-19 Research
- Enhanced Recovery After Surgery
- SARS-CoV-2 detection and testing
University Hospital Heidelberg
2021-2022
Heidelberg University
2020-2022
German Cancer Research Center
2022
Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed describe international variation in drain placement and the safety this practice.COMPASS (COMPlicAted intra-abdominal collectionS Surgery) was prospective, international, cohort which enrolled consecutive adults undergoing (February March 2020). The primary outcome...
There is low-certainty evidence on the impact of extended pharmacological prophylaxis venous thromboembolism-associated morbidity and mortality. The aim this study was to determine efficacy safety after major abdominopelvic surgery for prevention clinically relevant thromboembolism hospital discharge. CArdiovaSCulAr outcomes abDominal surgEry (CASCADE) a prospective, international, cohort into which consecutive adult patients undergoing were enrolled (January-May 2022). Extended considered...
Abstract Background Postoperative complications following major abdominal surgery are frequent despite progress in surgical technique and perioperative care. Early enhanced postoperative mobilisation has been advocated to reduce complications, but it is still unknown whether can independently improve outcomes after surgery. Fitness trackers (FTs) a promising tool mobilisation, their effect on recovery not investigated clinical trials. Methods This multicentre randomised controlled trial with...
Intraductal papillary mucinous neoplasms (IPMNs) are premalignant lesions of pancreatic cancer. An accurate serum biomarker, which allows earlier identification asymptomatic individuals with high-risk for developing cancer, is urgent need. Apolipoprotein A2-isoforms (apoA2-i) have previously been identified as biomarkers in This study investigates a potential clinical application the apoA2-i risk stratification IPMN and associated The concentrations were retrospectively determined 523...
Background Most data on COVID-19 was collected in hospitalized cases. Much less is known about the spectrum of disease entire populations. In this study, we examine a representative cohort primarily symptomatic cases an administrative district Southern Germany. Methods We contacted all confirmed SARS-CoV-2 district. Consenting participants answered retrospective survey either via telephone, electronically or mail. Clinical and sociodemographic features were compared between non-hospitalized...
(1) Background: A reliable non-invasive distinction between low- and high-risk pancreatic intraductal papillary mucinous neoplasms (IPMN) is needed to effectively detect IPMN with malignant potential. This would improve preventative care reduce the risk of developing cancer overtreatment. The present study aimed at exploring presence autoreactive antibodies in blood patients various grades dysplasia. (2) Methods: single-center cohort was studied composed 378 serum samples from low-grade (n =...
Abstract Background After infection with severe acute respiratory syndrome coronavirus (SARS-CoV-2), Immunoglobulin G (IgG) antibodies and virus-specific neutralizing (nAbs) develop. This study describes antibody responses in a cohort of recovered COVID-19 patients to identify predictors. Methods We recruited confirmed SARS-CoV-2 from Heidelberg, Germany. Blood samples were collected three weeks after symptoms ended. Participants high titers invited for follow-up visits. IgG measured by the...