A5036536314- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
- Anorectal Disease Treatments and Outcomes
- COVID-19 and healthcare impacts
- Esophageal and GI Pathology
- Appendicitis Diagnosis and Management
- Pancreatic and Hepatic Oncology Research
- Cancer Cells and Metastasis
- Hip and Femur Fractures
- Pelvic floor disorders treatments
- Cancer Genomics and Diagnostics
- Enhanced Recovery After Surgery
- Gastroesophageal reflux and treatments
- Pelvic and Acetabular Injuries
- Stoma care and complications
- Trauma and Emergency Care Studies
- Diverticular Disease and Complications
- Hernia repair and management
- Cancer, Hypoxia, and Metabolism
- Vitamin D Research Studies
University of Cyprus
2020-2025
University of Edinburgh
2024
Nicosia General Hospital
2020-2023
Worcestershire Acute Hospitals NHS Trust
2017-2021
University of Birmingham
2020-2021
NIHR Birmingham Biomedical Research Centre
2021
Yorkshire Cancer Research
2021
Urology Foundation
2021
Association for Cancer Surgery
2021
AstraZeneca (Brazil)
2020
Complete mesocolic excision (CME) with central vessel ligation (CVL) as performed in Erlangen offers the best long-term outcome for colon cancer. The aim of this study was to assess specimens after laparoscopic vs open CME-CVL macroscopically and morphometrically patients left right cancers.All were freshly photographed. Precise tumour morphometry grading surgical plane described by pathologists Leeds, UK.Thirty-four from right-sided cancers divided into 18 transverse (nine nine open) 16...
Malnutrition is a risk factor for postoperative morbidity but the optimal tool assessment of malnutrition unclear. This prospective multicentre cohort study. Consecutive patients undergoing elective or emergency major abdominal surgery benign malignant disease in 12 Greek hospitals between January 2022 and December 2023 were included. Patients unable to provide nutrition history and/or informed consent excluded. Subjective global (SGA) was used as reference standard diagnosis. GLIM (global...
There is low-certainty evidence on the impact of extended pharmacological prophylaxis venous thromboembolism-associated morbidity and mortality. The aim this study was to determine efficacy safety after major abdominopelvic surgery for prevention clinically relevant thromboembolism hospital discharge. CArdiovaSCulAr outcomes abDominal surgEry (CASCADE) a prospective, international, cohort into which consecutive adult patients undergoing were enrolled (January-May 2022). Extended considered...
Colon cancer surgery is a complex clinical pathway and traditional quality metrics may exhibit significant variability between hospitals healthcare providers. The Textbook Outcome (TO) composite marker capturing the fraction of patients, in whom all desired short-term outcomes care are realised. aim present study was to assess TO series non-metastatic colon patients treated with curative intent, emphasis on long-term survival.Stage I-III who underwent colectomy following Complete Mesocolic...
<i>Background:</i> Laparoscopic resection of the rectum is still under scrutiny for its adequacy oncological clearance. <i>Aim:</i> To assess lymph node yield after laparoscopic total mesorectal excision (TME) rectal cancer as compared to open approach. <i>Methods:</i> 74 patients with middle and low were prospectively randomized in two groups. Group A included 39 who had an TME (35 anterior (LARR) 4 abdominoperineal (APR)). In group B, there 34 a (27 LARR...
Abstract Background Emergency laparotomy (EL) is accompanied by high post‐operative morbidity and mortality which varies significantly between countries populations. The aim of this study to report outcomes emergency in Greece compare them with the results National Laparotomy Audit (NELA). Methods This a multicentre prospective cohort undertaken 01.2019 05.2020 including consecutive patients subjected EL 11 Greek hospitals. was defined according NELA criteria. Demographics, clinical...
In rectal cancer management, accurate staging by magnetic resonance imaging, neo-adjuvant treatment with the use of radiotherapy, and total mesorectal excision have resulted in remarkable improvement oncological outcomes. However, there is substantial discrepancy therapeutic approach failure to adhere international guidelines among different Greek-Cypriot hospitals. The present aim aid multidisciplinary management cancer, considering both local special characteristics our healthcare system...
Depending on the extent of left colon resection, splenic flexure mobilization is sometimes necessary to achieve a tension-free anastomosis. The aim study was assessment necessity and impact morbidity for laparoscopic colectomy with anastomosis cancer located distally flexure.Patients subjected carcinoma at any site from descending distal rectum 2004 2010 were reviewed. Comparisons made between cases without mobilization.A total 229 patients operated or rectal cancer. There no difference...
Laparoscopic repair of paraesophageal hernia (PEH) involves removal the sac, cruroplasty, and fundoplication. Mesh application to cruroplasty seems reduce recurrence rate, but may be associated with dysphagia. The aim study was review clinical laboratory outcomes a series patients PEH after laparoscopic repair. Patients PEH, who had 1-year postoperative follow-up, were included in study. Pre- testing symptom questionnaires, barium esophagogram, pH-monitoring, swallow testing. In first half...
Vitamin D deficiency has been associated with increased colorectal cancer (CRC) incidence risk and mortality. mediates its action through the binding of vitamin receptor (VDR), polymorphisms VDR might explain these inverse associations. The aim study was investigation relevance rs731236; Thermus aquaticus I (TaqI), rs7975232; Acetobacter pasteurianus sub. (ApaI), rs2228570; Flavobacterium okeanokoites (FokI) rs1544410, Bacillus stearothermophilus (BsmI) gene to carcinogenesis progression....
The purpose of the current study is to investigate prognostic significance M2 isoform pyruvate kinase (PKM2) mRNA expression loss in patients with operable colon cancer (CC). Two hundred sixty-two specimens from stage-III or high-risk stage-II CC (group-A) treated adjuvant fluoropyrimidine and oxaliplatin chemotherapy (FOLFOX), 118 metastatic (group-B) FOLFOX, 104 (group-C) irinotecan-based were analyzed for PKM2, TS, ERCC1, MYC, NEDD9 expression, as well KRAS exon2 BRAFV600E mutations. High...