- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Hemodynamic Monitoring and Therapy
- Cardiac Ischemia and Reperfusion
- Airway Management and Intubation Techniques
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Anesthesia and Pain Management
- Anesthesia and Neurotoxicity Research
- Cardiac Arrest and Resuscitation
- Mitochondrial Function and Pathology
- Hip and Femur Fractures
- Peripheral Artery Disease Management
- Radiation Effects and Dosimetry
- Chemical Reactions and Isotopes
- Cardiac electrophysiology and arrhythmias
- Acute Kidney Injury Research
- Delphi Technique in Research
- Protist diversity and phylogeny
- Smoking Behavior and Cessation
- Blood transfusion and management
- Protein Kinase Regulation and GTPase Signaling
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Anesthesia and Sedative Agents
- Adipose Tissue and Metabolism
University of Bristol
2019-2025
North Bristol NHS Trust
2008-2025
Southmead Hospital
2006-2023
NIHR Bristol Biomedical Research Centre
2023
At Bristol
2018
Ação Educativa
2018
TIE Kinetix (Germany)
2018
Bristol Royal Infirmary
2006-2008
Stellenbosch University
1991-2006
St. Mary’s Hospital
2006
Detailed contemporary knowledge of the characteristics surgical population, national anaesthetic workload, techniques and behaviours are essential to monitor productivity, inform policy direct research themes. Every 3-4 years, Royal College Anaesthetists, as part its National Audit Projects (NAP), performs a snapshot activity survey in all UK hospitals delivering anaesthesia, collecting patient-level encounter data from cases under care an anaesthetist. During November 2021, NAP7,...
Summary The 7th National Audit Project of the Royal College Anaesthetists studied peri‐operative cardiac arrest in UK, a topic importance to patients, anaesthetists and surgeons. Here we report results 12‐month registry, from 16 June 2021 15 2022, focusing on epidemiology clinical features. We reviewed 881 cases arrest, giving an incidence 3 10,000 anaesthetics (95%CI 3.0–3.5 per 10,000). Incidence varied with patient surgical factors. Compared denominator survey activity, patients arrest:...
Complications and critical incidents arising during anaesthesia due to patient, surgical or anaesthetic factors, may cause harm themselves progress more severe events, including cardiac arrest death. As part of the 7th National Audit Project Royal College Anaesthetists, we studied a prospective national cohort unselected patients. Anaesthetists recorded anonymous details all cases undertaken over 4 days at their site through an online survey. Of 416 hospital sites invited participate, 352...
Summary There is growing evidence that anaesthetic trainees experience, and may be particularly susceptible to, high levels of work stress, burnout depression. This concern for the safety wellbeing these doctors patients they treat. To date, there has been no in‐depth evaluation issues among UK to examine which groups most affected, identify professional personal factors with are associated. We conducted an anonymous electronic survey determine prevalence perceived risk burnout/depression...
Cardiac arrest in the peri-operative period is rare but associated with significant morbidity and mortality. Current reporting systems do not capture many such events, so there an incomplete understanding of incidence outcomes. As cardiac rare, hospitals may only see a small number cases over long periods, anaesthetists be involved for years. Therefore, large-scale prospective cohort needed to gain deep events leading up arrest, management itself patient Consequently, Royal College...
Summary The 7th National Audit Project of the Royal College Anaesthetists studied peri‐operative cardiac arrest in UK, a topic importance to patients, anaesthetists and surgeons. We report results 12‐month registry phase, from 16 June 2021 15 2022, focusing on management outcomes. Among 881 cases arrest, initial rhythm was non‐shockable 723 (82%) cases, most commonly pulseless electrical activity. There were 665 (75%) patients who survived event 384 (52%) hospital discharge. A favourable...
Summary The Royal College of Anaesthetists' 7th National Audit Project baseline survey assessed knowledge, attitudes, practices and experiences peri‐operative cardiac arrests among UK anaesthetists Anaesthesia Associates. We received 10,746 responses, representing a 71% response rate. In‐date training in adult paediatric advanced life support was reported by 9646 (90%) 7125 (66%) anaesthetists, respectively. There were 8994 (84%) respondents who confident leading arrest, with males more than...
Summary We report the results of Royal College Anaesthetists' 7th National Audit Project organisational baseline survey sent to every NHS anaesthetic department in UK assess preparedness for treating peri‐operative cardiac arrest. received 199 responses from 277 departments, representing a 72% response rate. Adult and paediatric care was provided by 188 (95%) 165 (84%) hospitals, respectively. There no intensive unit on‐site 144 (87%) hospitals caring children, meaning transfer critically...
Tobacco smoking is the leading behavioural risk factor for cardiovascular disease and may double of long-term mortality after coronary artery bypass grafting (CABG) [1, 2]. Smoking cessation interventions, which combine pharmacological treatment support, are effective at supporting abstinence time surgery 12 months postoperatively [3]. However, remains more prevalent among those patients undergoing (25%) than in general UK population (13%) [4, 5]. There limited contemporary evidence about...
There is low-certainty evidence on the impact of extended pharmacological prophylaxis venous thromboembolism-associated morbidity and mortality. The aim this study was to determine efficacy safety after major abdominopelvic surgery for prevention clinically relevant thromboembolism hospital discharge. CArdiovaSCulAr outcomes abDominal surgEry (CASCADE) a prospective, international, cohort into which consecutive adult patients undergoing were enrolled (January-May 2022). Extended considered...
Summary The 7th National Audit Project of the Royal College Anaesthetists studied peri‐operative cardiac arrest in UK. We report results vascular surgery cohort from 12‐month case registry, 16 June 2021 to 15 2022. Anaesthesia for accounted 2% UK anaesthetic caseload and included 69 (8%) reported arrests, giving an estimated incidence 1 670 anaesthetics (95%CI 520–830). high‐risk nature population is reflected by proportion patients who were ASA physical status 4 (30, 43%) or 5 (19, 28%);...
Case series and a post hoc subgroup analysis of large randomized trial have suggested potential benefit in treating ruptured abdominal aortic aneurysms (rAAAs) using endovascular aneurysm repair (EVAR) with local anaesthesia (LA) rather than general (GA). The uptake outcomes LA clinical practice remain unknown.The UK National Vascular Registry was interrogated for patients presenting rAAA managed EVAR under different modes between 1 January 2014 31 December 2016. primary outcome in-hospital...
Summary Anaesthetists experience unique stressors, and recent evidence suggests a high prevalence of stress burnout in trainee anaesthetists. There has been no in‐depth qualitative analysis to explore this further. We conducted semi‐structured interviews contributory potentially protective factors the development perceived stress, burnout, depression low work satisfaction. sampled purposively among participants Satisfaction Wellbeing Anaesthetic Training study, reaching data saturation at 12...