A5075866284- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Total Knee Arthroplasty Outcomes
- Musculoskeletal pain and rehabilitation
- Child and Adolescent Psychosocial and Emotional Development
- Innovations in Medical Education
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Policy and Management
- Primary Care and Health Outcomes
- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Orthopedic Surgery and Rehabilitation
- Child and Adolescent Health
- Airway Management and Intubation Techniques
- Physics and Engineering Research Articles
- Pain Management and Treatment
- Patient-Provider Communication in Healthcare
- Surgical site infection prevention
- Bone fractures and treatments
- Health disparities and outcomes
- Sports Science and Education
- Frailty in Older Adults
- Bone and Joint Diseases
- Empathy and Medical Education
- Healthcare Operations and Scheduling Optimization
University of Exeter
2018-2024
Philadelphia College of Osteopathic Medicine
2024
NHS Ayrshire and Arran
2023
University of Bath
2010-2019
Heavitree Hospital
2018
Applied Mathematics (United States)
2008-2017
Royal National Hospital for Rheumatic Diseases
2003-2017
Engineering and Physical Sciences Research Council
2008-2017
Edinburgh Royal Infirmary
2015
British Nuclear Medicine Society
2015
In the UK, thousands of people with high cardiovascular risk are being identified by a national risk-assessment programme (NHS Health Checks). Waste Waist is an evidence-informed, theory-driven (modified Action Process Approach), group-based intervention designed to promote healthy eating and physical activity for risk. This pilot randomised controlled trial aimed assess feasibility delivering in UK primary care conducting full-scale trial. We also conducted exploratory analyses changes...
<b>Background:</b> Rheumatoid arthritis (RA) is associated with increased cardiovascular mortality for reasons which are insufficiently understood. Chronic inflammation may impair vascular function and lead to an increase of arterial stiffness, important determinant risk. <b>Objective:</b> To investigate the augmentation index (AIx) as a measure stiffness in patients RA, free disease or risk factors, by means matched cohort pilot study. <b>Method:</b> Patients diagnosis aged 50 years...
Between June 1988 and December 1997, we treated 332 babies with 546 dysplastic hips in a Pavlik harness for primary developmental dysplasia of the hip as detected by selective screening programme Southampton. Each was managed strict protocol including ultrasonic monitoring treatment harness. The group prospectively studied during mean period 6.5 +/- 2.7 years follow-up 89.9%. acetabular index (AI) centre-edge angle Wiberg (CEA) were measured on annual radiographs to determine development...
To determine if depression of creatinine clearance after administration contrast medium may be prevented with theophylline.A nonionic, low-osmolality (iopamidol) or an ionic, high-osmolality (sodium diatrizoate) was administered to 93 patients. Before the examination, these patients were given theophylline a placebo orally. There also 30 who received adenosine-uptake inhibitor (dipyridamole). Creatinine and urinary adenosine levels measured before angiography.Creatinine decreased 18% +/- 4...
Acceptance and commitment therapy (ACT) is a developing approach for chronic pain. The current study was designed to pilot test brief, widely inclusive, local access format of ACT in UK primary care setting. Seventy-three participants (68.5% women) were randomized either or treatment as usual (TAU). Many the aged 65 years older (27.6%), diagnosed with fibromyalgia (30.2%) depression (40.3%), had longstanding pain (median = 10 years). Standard clinical outcome measures included disability,...
Anxiety in children is common, impairs everyday functioning, and increases the risk of severe mental health disorders adulthood. We investigated effect a classroom-based cognitive behaviour therapy prevention programme (FRIENDS) on anxiety symptoms children.Preventing Children though Education Schools (PACES) three-group parallel cluster randomised controlled trial. Interventions were given between September, 2011, July, 2012, with schools as unit allocation individual participants analysis....
Knowledge of the position one's limbs is an essential component daily function and relies on complex interactions sensorimotor body schema-related information. Those with Complex Regional Pain Syndrome (CRPS) express difficulty in knowing where their affected limb positioned. The aim this study was to determine degree which experimental data supported reported sense. A controlled design used measure upper accuracy amongst those CRPS one arm. Position individually measured both arms compared...
Process evaluation is important for improving theories of behavior change and behavioral intervention methods. The present study reports on the process outcomes a pilot test theoretical model (the Model Lifestyle Behavior Change; PMLBC) underpinning an evidence-informed, theory-driven, group-based designed to promote healthy eating physical activity people with high cardiovascular risk. 108 at risk diabetes or heart disease were randomized weight management targeting diet plus usual care,...
The loss of GPs in the early stages their careers is contributing to GP workforce crisis. Recruitment UK remains below numbers needed support demand for care.To explore reasons why leave general practice early.A mixed methods study using online survey data triangulated with qualitative interviews.Participants were aged <50 years who had left English Medical Performers List last 5 (2009-2014). A total 143 leavers participated an survey, which 21 took part recorded telephone interviews. Survey...
Background Rapid spread of coronavirus disease 2019 (COVID-19) has affected people with intellectual disability disproportionately. Existing data does not provide enough information to understand factors associated increased deaths in those disability. Establishing who is at high risk important developing prevention strategies, given or comorbidities may be different the general population. Aims To identify comorbidities, demographic and clinical individuals have died from COVID-19. Method...
Mobility limitations in old age can greatly reduce quality of life, generate substantial health and social care costs, increase mortality. Through the Retirement Action (REACT) trial, we aimed to establish whether a community-based active ageing intervention could prevent decline lower limb physical functioning older adults already at increased risk mobility limitation.
Objective: To determine whether an early intervention using a psychological debriefing format is effective in preventing distress child road traffic accident survivors. Design: Randomised controlled trial. Setting: Accident and Emergency Department, Royal United Hospital, Bath. Subjects: 158 children aged 7–18. Follow‐up assessment completed eight months post with 132 (70/82 of the experimental group 62/76 control group). Main outcome measures: Self‐completed measures distress; fulfilment...
Objective: The evaluation of a community-based exercise and education scheme for stroke survivors. Design: A single blind parallel group randomized controlled trial. Setting: Leisure community centres in the south-west England. Subjects: Stroke survivors (median (IQR) time post 10.3 (5.4—17.1) months). 243 participants were to standard care (124) or intervention (119). Intervention: Exercise schemes held twice weekly eight weeks, facilitated by volunteers qualified instructors (supported...
Background Anxiety in children is common, impairs everyday functioning and increases the risk of severe mental health disorders adulthood, yet few with anxiety are identified referred for treatment. Objective To investigate clinical effectiveness cost-effectiveness a universal school-based preventative programme (FRIENDS) reducing symptoms low mood. Design Cluster randomised controlled trial. Schools ( n = 41) were randomly assigned after recruitment on 1 : basis to health-led FRIENDS,...
Summary There is growing evidence that anaesthetic trainees experience, and may be particularly susceptible to, high levels of work stress, burnout depression. This concern for the safety wellbeing these doctors patients they treat. To date, there has been no in‐depth evaluation issues among UK to examine which groups most affected, identify professional personal factors with are associated. We conducted an anonymous electronic survey determine prevalence perceived risk burnout/depression...
ABSTRACT Aims To explore trends in and predictors of second‐hand smoke (SHS) exposure children. identify whether inequalities SHS are changing over time. Design Repeated cross‐sectional study with data from eight annual surveys conducted an 11‐year period 1996 to 2006. Setting England. Participants Nationally representative samples children aged 4–15 years living private households. Measurements Saliva cotinine (4–15‐year‐olds), current smoking status (8–15‐year‐olds), parents carers, the...
Objective. To determine whether the mortality in a cohort of patients with psoriatic arthritis (PsA) from single center UK is significantly different general population. Methods. Patients who were entered onto PsA database at Royal National Hospital for Rheumatic Diseases, Bath, between 1985 and 2007 included this study. Information on patient deaths was collected retrospectively. The Health Service (NHS) Strategic Tracing used to establish which alive had died. Date cause death confirmed by...
Abstract Introduction The pathology of ankylosing spondylitis (AS) suggests that certain cytokines and matrix metalloproteinases (MMPs) might provide useful markers disease activity. Serum levels some MMPs have been found to be elevated in active disease, but there is a general lack information about biomarker profiles AS how these are related activity function. purpose this study was investigate whether clinical measures function associated with particular circulating MMPs. Methods...