Georgia Dimopoulou
A5059012958- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Hepatitis B Virus Studies
- Nanoplatforms for cancer theranostics
- Lung Cancer Treatments and Mutations
- Occupational and environmental lung diseases
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Appendicitis Diagnosis and Management
- COVID-19 and healthcare impacts
- Immune Cell Function and Interaction
- Educational Strategies and Epistemologies
- Lung Cancer Research Studies
- Hip and Femur Fractures
- Science Education and Pedagogy
- Sepsis Diagnosis and Treatment
- Cancer Research and Treatments
- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Education and Critical Thinking Development
- Pleural and Pulmonary Diseases
- Effects of Radiation Exposure
- Pelvic and Acetabular Injuries
Frontier Science Foundation-Hellas
2019-2025
National and Kapodistrian University of Athens
2019-2024
Evangelismos Hospital
2023-2024
University of Patras
2019-2024
Hella (Germany)
2024
Agios Pavlos General Hospital
2019-2023
Hospital Clínico San Carlos
2021
University of Lausanne
2021
Hospital Braga
2020
King's College Hospital NHS Foundation Trust
2020
Abstract Developing strategies to inflame tumors is critical for increasing response immunotherapy. Here, we report that low-dose radiotherapy (LDRT) of murine promotes T-cell infiltration and enables responsiveness combinatorial immunotherapy in an IFN-dependent manner. Treatment efficacy relied upon mobilizing both adaptive innate immunity depended on cytotoxic CD4+ CD8+ T cells. LDRT elicited predominantly cells with features exhausted effector cells, a subset expressing NKG2D exhibiting...
PURPOSE CD276 (B7-H3) is an immunoregulatory protein that plays important role in the inhibition of T-cell function. overexpressed on a variety human solid cancer cells with limited expression normal tissues, making it appealing target for innovative immunotherapy approaches. Pleural mesothelioma (PM) highly aggressive disease need new treatment options. Our objective was to investigate multicenter PM cohort European Thoracic Oncology Platform Mesoscape project and correlate results...
Abstract Background Emergency laparotomy (EL) is accompanied by high post‐operative morbidity and mortality which varies significantly between countries populations. The aim of this study to report outcomes emergency in Greece compare them with the results National Laparotomy Audit (NELA). Methods This a multicentre prospective cohort undertaken 01.2019 05.2020 including consecutive patients subjected EL 11 Greek hospitals. was defined according NELA criteria. Demographics, clinical...
Abstract Over the past decades, science education researchers have suggested Inquiry-Based Science Education (IBSE) teaching interventions for classes. In this article, we argue that IBSE’s basic principles can be traced back to Jean-Jacques Rousseau’s work Emile or On (1762). First, will look at rationale. Then turn and outline educational ideas concerning education. We show practices are very similar those of IBSE. Yet despite their vivid similarities, Rousseau seems pursue epistemic...
Exploratory research showed that female oncologists are frequently under-represented in leadership roles. European Society for Medical Oncology (ESMO) Women (W4O) therefore implemented gender equality programs career development and established international studies on representation at all stages of the oncology pathway.For 2017-2019, data were collected (i) first last authorship publications five major journals (ii) women positions oncology-as invited speakers National/International...
Background: The aim of this study was to investigate the usefulness serum procalcitonin (PCT), C-reactive protein (CRP), neutrophil lymphocyte count ratio (NLR), and their combination, in distinguishing candidemia from bacteremia intensive care unit (ICU) patients. Methods: This is a retrospective ICU patients with documented bloodstream infections (BSIs) both PCT CRP measurements on day positive blood sample. Illness severity assessed by sequential organ failure assessment (SOFA) score...
The current work investigates the relationship between shape of an isolator a concentric rotary piston compressor and secondary peak pressure developed during each operating cycle. This is when passes through cavity, it negative for efficiency. aim this paper to identify cavity that minimizes improve study covers five different cavities may be used in such compressors. Contrary our expectations, conclusion best geometry one can manufactured with CNC machining. 3D printing also produces...
As management and prevention strategies against COVID-19 evolve, it is still uncertain whether prior exposure to immune checkpoint inhibitors (ICIs) affects severity in patients with cancer. In a joint analysis of ICI recipients from OnCovid (NCT04393974) European Society for Medical Oncology (ESMO) CoCARE registries, we assessed mortality SARS-CoV-2 vaccinated unvaccinated cancer explored immune-related adverse events (irAEs) influenced outcome COVID-19. The study population consisted 240...
Aim: This study sought to evaluate the effectiveness of lactate/albumin ratio for ICU mortality prediction in a large cohort patients with severe Coronavirus Disease-2019 (COVID-19) admitted intensive care unit (ICU). Methods: is single-center retrospective prospectively collected data derived from COVID-19 dataset all critically ill an academic ICU. Data were used determine relation between and other laboratory parameters measured on first day stay prognostic performance prediction....
This study sought to evaluate the effectiveness of lactate/albumin ratio for ICU mortality prediction in a large cohort patients with severe Coronavirus Disease-2019 (COVID-19) admitted an intensive care unit (ICU).
Background: : The coexistence of two or more types lymphoma within the same organ at time diagnosis is defined as composite lymphoma, a rare disease that has recently been identified in literature. Pointedly, concurrence may be Hodgkin with Non-Hodgkin [NHL], either B T cells, different entities NHLs. Furthermore, this condition described concurrently sequentially. In order for to established, distinct clones should proven by morphological and laboratory tests. Case presentation:: Herein, we...
COVID-19 has significantly affected patients with cancer and revealed unanticipated challenges in securing optimal care across different disciplines. The European Society for Medical Oncology CAncer REgistry (ESMO-CoCARE) is an international, real-world database, collecting data on the natural history, management, outcomes of SARS-CoV-2 infection.This 2nd CoCARE analysis, jointly Belgian (Belgian Oncology, BSMO) Portuguese (Portuguese PSMO) registries, from January 2020 to December 2021. aim...
Abstract Purpose Emergency laparotomy (EL) is a common operation with high risk for postoperative complications, thereby requiring accurate stratification to manage vulnerable patients optimally. We developed and internally validated predictive model of serious complications after EL. Methods Data eleven carefully selected candidate predictors 30-day (Clavien-Dindo grade > = 3) were extracted from the HELAS cohort EL in 11 centres Greece Cyprus. Logistic regression Least Absolute...
Although coronavirus disease 2019 (COVID-19)-induced changes in laboratory parameters patients upon admission have been well-documented, information on their temporal is limited. The present study describes the trends and effect of dexamethasone treatment these parameters, with COVID-19 intensive care unit (ICU). Routine namely white blood cell (WBC), neutrophil, lymphocyte platelet (PLT) counts, fibrinogen, C-reactive protein (CRP), lactate dehydrogenase (LDH) albumin concentrations, were...
Pleural mesothelioma (PM) is an aggressive malignancy with poor prognosis. Although histology and pathologic stage are important prognostic factors, better biomarkers needed. The ribosomal protein S6 a downstream target of the phosphatidylinositol 3-kinase (PI3K) pathway involved in synthesis cell proliferation. In previous studies, low phosphorylated (pS6) immunoreactivity was significantly correlated longer progression-free survival (PFS) overall (OS) PM patients. We aimed to correlate pS6...