Sergio Alfieri
A5039218536- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Surgical Treatments
- Gastrointestinal Tumor Research and Treatment
- Gallbladder and Bile Duct Disorders
- Cancer Genomics and Diagnostics
- Colorectal Cancer Screening and Detection
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal disorders and treatments
- Colorectal and Anal Carcinomas
- COVID-19 and healthcare impacts
- Colorectal Cancer Treatments and Studies
- Appendicitis Diagnosis and Management
- Renal cell carcinoma treatment
- Hernia repair and management
- Radiomics and Machine Learning in Medical Imaging
- Intraperitoneal and Appendiceal Malignancies
- Cancer Cells and Metastasis
- Hepatocellular Carcinoma Treatment and Prognosis
- Intestinal and Peritoneal Adhesions
Università Cattolica del Sacro Cuore
2016-2025
Agostino Gemelli University Polyclinic
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2024
Amsterdam University Medical Centers
2024
University of Amsterdam
2024
Oslo University Hospital
2023
University of Bologna
2023
Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie
2020-2022
Vita-Salute San Raffaele University
2022
University of Birmingham
2020-2021
Objective: To develop and update evidence- consensus-based guidelines on laparoscopic robotic pancreatic surgery. Summary Background Data: Minimally invasive surgery (MIPS), including surgery, is complex technically demanding. Minimizing the risk for patients requires stringent, evidence-based guidelines. Since International Miami Guidelines MIPS in 2019, new developments key publications have been reported, necessitating an update. Methods: Evidence-based 22 topics 8 domains were proposed:...
Objective: The REDISCOVER consensus conference aimed at developing and validate guidelines on the perioperative care of patients with borderline resectable (BR-) locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC). Summary Background Data: Coupled improvements in chemotherapy radiation, contemporary approach to surgery supports resection BR-PDAC and, a lesser extent, LA-PDAC. Guidelines outlining selection for these are lacking. Methods: Scottish Intercollegiate Network (SIGN)...
In Brief Objective: To evaluate whether the various surgical treatment reserved for ilioinguinal, iliohypogastric, and genital branch of genitofemoral nerves, during open hernia mesh repair, is effective in reducing chronic postoperative pain. Background: Interest groin pain following herniorrhaphy has escalated, recent years, due both to legal implications. However, much debate still exists concerning which reserve 3 inguinal sensory nerves. Methods: A multicentric prospective study...
Pancreatic ductal adenocarcinoma (PDAC) is characterized by extremely poor prognosis. PDAC presents with molecularly distinct subtypes, the basal-like one being associated enhanced chemoresistance. Splicing dysregulation contributes to PDAC; however, its involvement in subtype specification remains elusive. Herein, we uncover a subtype-specific splicing signature prognosis and factor Quaking (QKI) as determinant of signature. Single-cell sequencing analyses highlight QKI marker phenotype....
Abstract The existing Intraductal Papillary Mucinous Neoplasm (IPMN) risk stratification relies on clinical and histological factors, resulting in inaccuracies leading to suboptimal treatment. This is due the lack of appropriate molecular markers that can guide patients toward best therapeutic options. Here, we assess confirm subtype-specific for IPMN across two independent cohorts using Spatial Transcriptomics (ST) technologies. Specifically, identify HOXB3 ZNF117 as Low-Grade Dysplasia,...
Journal Article Extensive versus limited lymph node dissection for gastric cancer: A comparative study of 320 patients Get access F Pacelli, Pacelli Istituto di Clinica Chirurgica, Universitá Cattolica del Sacro Cuore, Largo A. Gemelli 8, 00168, Rome, Italy Correspondence to: Dr F. Search other works by this author on: Oxford Academic Google Scholar G B Doglietto, Doglietto R Bellantone, Bellantone S Alfieri, Alfieri Sgadari, Sgadari Medica, Crucitti British Surgery, Volume 80, Issue 9,...
Main Recommendations 1 We recommend post-surgery endoscopic surveillance for CRC patients after intent-to-cure surgery and appropriate oncological treatment both local distant disease.Strong recommendation, low quality evidence. 2 a high perioperative colonoscopy before or within 6 months following surgery.Strong 3 performing year moderate 4 do not an intensive strategy, e. g. annual colonoscopy, because of lack proven benefit.Strong 5 After the first surgery, we suggest second should be...
BACKGROUND Arterial hypotension during major surgery is related to postoperative complications and mortality. Both fluids vasopressors increase blood pressure (BP) by inducing different physiological response. We devised a protocol which relies on dynamic arterial elastance (Ea dyn ) guide BP optimisation abdominal surgery, tested its effectiveness tissue perfusion. OBJECTIVE explore if an Ea -based could affect lactate levels, fluid administration, clinical complications. DESIGN randomised...
Increased proinsulin secretion, which characterizes type 2 diabetes and insulin resistance, may be due to an intrinsic, primitive defect in processing or secondary increased demand on β-cells (hyperinsulinemia resistance). An alternative way investigate the relation between relative hyperproinsulinemia secretory is study dynamic changes proinsulin-to-insulin ratio after partial pancreatectomy, a model of acute β-cell workload remaining pancreas. To pursue this aim, patients without diabetes,...