A5103200789- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Treatments and Studies
- Gastrointestinal disorders and treatments
- Renal cell carcinoma treatment
- Intestinal Malrotation and Obstruction Disorders
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Bariatric Surgery and Outcomes
- Cancer Genomics and Diagnostics
- Abdominal Trauma and Injuries
- Colorectal Cancer Surgical Treatments
- Esophageal and GI Pathology
- Appendicitis Diagnosis and Management
- Abdominal vascular conditions and treatments
- COVID-19 and healthcare impacts
- Intraoperative Neuromonitoring and Anesthetic Effects
Centre Hospitalier du Mans
2021-2025
Centre Hospitalier de Luxembourg
2020-2024
Universität Hamburg
2024
University Medical Center Hamburg-Eppendorf
2024
Fondazione Poliambulanza Istituto Ospedaliero
2015-2023
University of Padua
2021-2023
Azienda Ospedaliera di Padova
2021
Université de Strasbourg
2009-2021
Université de Montpellier
2019
Clinique Mutualiste Chirurgicale
2019
To assess outcome after a 2-stage hepatectomy procedure (TSHP) combined with portal vein embolization (PVE) in the treatment of patients unresectable multiple and bilobar colorectal liver metastases (MBCLM).Patients MBCLM are often considered for palliative chemotherapy only, due to too small future remnant (FRL). Recently, right simultaneous left wedge resections previous PVE has been reported curative intent. However, growth metastatic nodules FRL can be more rapid than that nontumoral...
To investigate whether sinusoidal injury (SI) was associated with a worse outcome after hepatectomy in patients colorectal liver metastases (CRLM).Correlation between SI and oxaliplatin-based chemotherapy (OBC) recently shown CRLM. However, it has yet to be fully clarified affects functional reserve hepatectomy.Between 2003 2005, 90 CRLM who underwent an elective preoperative chemotherapies were included. Diagnosis of established pathologically the nontumoral parenchyma resected specimens,...
Objective: The REDISCOVER consensus conference aimed at developing and validate guidelines on the perioperative care of patients with borderline resectable (BR-) locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC). Summary Background Data: Coupled improvements in chemotherapy radiation, contemporary approach to surgery supports resection BR-PDAC and, a lesser extent, LA-PDAC. Guidelines outlining selection for these are lacking. Methods: Scottish Intercollegiate Network (SIGN)...
To assess short-term outcomes after minimally invasive (laparoscopic, robot-assisted, and hybrid) pancreatoduodenectomy (MIPD) versus open (OPD) among European centers.Current evidence on MIPD is based national registries or single expert centers. International, matched studies comparing for OPD are lacking.Retrospective propensity score study in 14 centers (7 countries) performing ≥10 MIPDs annually (2012-2017) 53 German/Dutch surgical registry OPDs (2014-2017). Primary outcome was 30-day...
Abstract Background As surgical resection of colorectal liver metastases (CLM) remains the only treatment for cure, efforts to extend indications include patients with multiple bilobar CLM have been made. This study evaluated long-term outcome, safety and efficacy two-stage hepatectomy (TSH) in a large cohort patients. Methods Patients undergoing surgery between December 1996 2009 were reviewed. The early postoperative outcomes as well patterns failure complete TSH its clinical implications...
To generate the first evaluation of risk factors for postoperative pulmonary complications (PPCs) after hepatectomy.Postoperative surgery are associated with significant morbidity and have been shown to increase length hospital stays. Several studies conducted identify PPCs abdominal surgery.Between January 2006 December 2009, 555 patients underwent elective hepatectomy. We prospectively collected retrospectively analyzed demographic data, pathological variables, conditions, preoperative,...
The role of minimally invasive distal pancreatectomy is still unclear, and whether robotic (RDP) offers benefits over laparoscopic (LDP) unknown because large multicentre studies are lacking. This study compared perioperative outcomes between RDP LDP.A international propensity score-matched included patients who underwent or LDP for any indication in 21 European centres from six countries that performed at least 15 pancreatectomies annually (January 2011 to June 2019). Propensity score...
Open surgery for pancreatic necrosis is associated with considerable morbidity and mortality. We report the results of a recently developed minimally invasive technique that we adopted in 1998.A descriptive explanation approach given together retrospective analysis patients who underwent retroperitoneal necrosectomy (MIRP) between August 1998 April 2002.There were 24 median (range) age 61 (29-75) years. The initial APACHE II score was 8 (2-21). All had infected at least 50% necrosis. In...
Abstract Background and Objectives Arterial resection (AR) has traditionally been considered as a contraindication to pancreatic for locally advanced adenocarcinoma. The objective was evaluate if with AR worthwhile. Methods Between January 1990 December 2008 the records of 26 consecutive patients who underwent curative‐intent adenocarcinoma pancreas (AR+ group) were matched 1:1 those whole series performed in our institution. final study population (n = 52) included two groups patients:...
Abstract Background Minimally invasive pancreatoduodenectomy (MIPD) is increasingly being performed because of perceived patient benefits. Whether conversion MIPD to open worsens outcome, and which risk factors are associated with conversion, unclear. Methods This was a post hoc analysis European multicentre retrospective cohort study patients undergoing (2012–2017) in ten medium-volume (10–19 MIPDs annually) four high-volume (at least 20 centres. Propensity score matching (1 : 1) used...
Abstract Background Recently, the first randomized trials comparing minimally invasive distal pancreatectomy (MIDP) with open (ODP) for non-malignant and malignant disease showed a 2-day reduction in time to functional recovery after MIDP. However, pancreatic ductal adenocarcinoma (PDAC), concerns have been raised regarding oncologic safety (i.e., radical resection, lymph node retrieval, survival) of MIDP, as compared ODP. Therefore, controlled trial MIDP ODP PDAC oncological is warranted....
Survival benefit, in patients with colorectal liver metastases (CLM) and hepatic pedicle lymph nodes (HPLN) involvement along the common artery celiac axis (area 2 or distal) has not been observed. However, these results are based on historical series, using suboptimal chemotherapy drugs.The aim of present study is to investigate impact HPLN survival after resection for CLM era new regimens.Between January 2000 June 2006, 45 high risk consecutive presenting all pathologically proven were...
To assess the effect of portal vein embolization (PVE) on intrahepatic recurrence rate after right hepatectomy for unilobar colorectal liver metastases (CLM).Recent research suggests that CLM could spread retrogradely through vein. PVE may reduce tumor shedding by occlusion distal branches. However, no study reported clinical resection.Between 1995 and 2003, 44 patients requiring a were operated in our institution. Right was performed 23 (group A) without 21 B). Surgical outcome site...