Carlo Lombardo
A5056360200- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Renal cell carcinoma treatment
- Diabetes Management and Research
- Cancer Genomics and Diagnostics
- Diabetes and associated disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Abdominal Trauma and Injuries
- Congenital Anomalies and Fetal Surgery
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic function and diabetes
- Esophageal and GI Pathology
- MRI in cancer diagnosis
- Trauma Management and Diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Diabetes Treatment and Management
- Congenital Diaphragmatic Hernia Studies
- Liver Disease and Transplantation
- Neuroendocrine Tumor Research Advances
- Cardiac, Anesthesia and Surgical Outcomes
University of Pisa
2017-2024
University of Messina
2024
Azienda Ospedaliera Universitaria Pisana
2017-2022
Soroka Medical Center
2017
San Salvatore Hospital
2017
Sefako Makgatho Health Sciences University
2017
University of Palermo
2010
Objective: The aim of this study was to compare oncological outcomes after minimally invasive distal pancreatectomy (MIDP) with open (ODP) in patients pancreatic ductal adenocarcinoma (PDAC). Background: Cohort studies have suggested superior short-term MIDP vs. ODP. Recent international surveys, however, revealed that surgeons concerns about the for PDAC. Methods: This is a pan-European propensity score matched including who underwent (laparoscopic or robot-assisted) ODP PDAC between...
Objective: The REDISCOVER consensus conference aimed at developing and validate guidelines on the perioperative care of patients with borderline resectable (BR-) locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC). Summary Background Data: Coupled improvements in chemotherapy radiation, contemporary approach to surgery supports resection BR-PDAC and, a lesser extent, LA-PDAC. Guidelines outlining selection for these are lacking. Methods: Scottish Intercollegiate Network (SIGN)...
To assess short-term outcomes after minimally invasive (laparoscopic, robot-assisted, and hybrid) pancreatoduodenectomy (MIPD) versus open (OPD) among European centers.Current evidence on MIPD is based national registries or single expert centers. International, matched studies comparing for OPD are lacking.Retrospective propensity score study in 14 centers (7 countries) performing ≥10 MIPDs annually (2012-2017) 53 German/Dutch surgical registry OPDs (2014-2017). Primary outcome was 30-day...
Abstract Background Western multicenter studies on distal pancreatectomy with celiac axis resection (DP-CAR), also known as the Appleby procedure, for locally advanced pancreatic cancer are lacking. We aimed to study overall survival, morbidity, mortality and impact of preoperative hepatic artery embolization (PHAE). Methods Retrospective cohort within European-African Hepato-Pancreato-Biliary-Association, DP-CAR between 1-1-2000 6-1-2016. Primary endpoint was survival. Secondary endpoints...
Distal pancreatectomy with celiac axis resection (DP-CAR) is a treatment option for selected patients pancreatic cancer involving the axis. A recent multicenter European study reported 90-day mortality rate of 16%, highlighting importance patient selection. The authors constructed risk score to predict and assessed oncologic outcomes. This retrospective cohort investigated undergoing DP-CAR at 20 centers from 12 countries (model design 2000–2016) three very-high-volume international in...
Duodenal graft complications are poorly reported of pancreas transplantation that can result in loss. Excluding patients with early failure, after a median follow-up period 126 months (range 23-198) duodenectomy was required 14 312 transplants (4.5%). All were insulin-independent at the time diagnosis. Reasons for included delayed duodenal perforation (n = 10, 71.5%) and refractory bleeding 4, 28.5%). In bleeding, total performed. perforation, preservation segment possible five but...
The prognostic value of carbohydrate antigen 125 (Ca 125) is emerging also in pancreatic cancer (PDAC). In this study, we aim to define the Ca resected PDAC head pancreas. This a single-center, retrospective study. Data from patients with pre-operative assay who underwent resection for between 2010 and 2018 were analyzed. As per National Comprehensive Cancer Guidelines, tumors classified resectable (R-PDAC), borderline (BR-PDAC), locally advanced (LA-PDAC). Kaplan-Meier method was used...
Newer chemotherapy regimens are reviving the role of pancreatectomy with arterial resection (PAR) in locally advanced pancreatic cancer. However, concerns about early outcomes and learning curve PAR remain. This study aimed to define postoperative results provide preliminary data on oncologic outcomes.
Abstract Surgical procedures are often impeded by bleeding and/or leakage of body fluids. These complications cannot always be resolved conventional surgical techniques. Hemopatch ® is a hemostatic patch that also functions as sealant. Here we document the effectiveness and safety for routine multiple disciplines. To this end, performed prospective, multicenter, single-arm, observational registry study. Patients were eligible if they had received during an open or minimally invasive...
Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive tumor with five-year survival of less than 6%. Chronic pancreatitis (CP), an inflammatory process in the pancreas, strong risk factor for PDAC. Several genetic polymorphisms have been discovered as susceptibility loci both CP and Since PDAC share consistent number epidemiologic factors, aim this study was to investigate whether specific also contribute susceptibility. We selected five common SNPs (rs11988997, rs379742, rs10273639,...
To assess postoperative 90-day outcomes after minimally invasive (laparoscopic/robot-assisted) total pancreatectomy (MITP) in selected patients versus open (OTP) among European centers.Minimally pancreatic surgery is becoming increasingly popular but data on MITP are scarce and multicenter studies comparing OTP lacking. It therefore remains unclear if a valid alternative.Multicenter retrospective propensity-score matched study including consecutive adult undergoing or for all indications at...
Abstract Background Treatment of pancreatic metastases (PM) from renal cell carcinoma (RCC) is still an issue between surgeons and oncologists, in the era target-therapy. Methods Data 26 patients undergoing resection PM extra-PM RCC, with R0 intention were retrospectively analysed. No one received adjuvant chemotherapy. Patients divided into two groups; Group A comprehends 14 who developed synchronous (5) or methacronous (9) extra-PM. B 12 that only. Results intraoperative mortality was...
Abstract Background: Pancreatic neuroendocrine tumors (PNETs) are rare neoplasms for which very little is known about either environmental or genetic risk factors. Only a handful of association studies have been performed so far, suggesting small number loci. Methods: To replicate the best findings, we selected 16 SNPs suggested in previous to be relevant PNET etiogenesis. We genotyped (rs16944, rs1052536, rs1059293, rs1136410, rs1143634, rs2069762, rs2236302, rs2387632, rs3212961,...