A5011787891- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Thermal Regulation in Medicine
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Neutropenia and Cancer Infections
- Pneumonia and Respiratory Infections
- Vitamin D Research Studies
- Pharmacological Effects and Toxicity Studies
- Cardiovascular Health and Disease Prevention
- Mechanical Circulatory Support Devices
- Pneumocystis jirovecii pneumonia detection and treatment
- Acute Kidney Injury Research
- Family and Patient Care in Intensive Care Units
- Nosocomial Infections in ICU
- Anesthesia and Sedative Agents
- Electrolyte and hormonal disorders
- Long-Term Effects of COVID-19
Agostino Gemelli University Polyclinic
2020-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2024
Università Cattolica del Sacro Cuore
2020-2023
<h3>Importance</h3> High-flow nasal oxygen is recommended as initial treatment for acute hypoxemic respiratory failure and widely applied in patients with COVID-19. <h3>Objective</h3> To assess whether helmet noninvasive ventilation can increase the days free of support COVID-19 compared high-flow alone. <h3>Design, Setting, Participants</h3> Multicenter randomized clinical trial 4 intensive care units (ICUs) Italy between October December 2020, end follow-up February 11, 2021, including 109...
Abstract Background In critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We designed a prospective observational study to describe profile HD TGC in cohort patients with severe infections. Results This was single centre, prospective, that conducted 20-bed mixed ICU 1500-bed teaching hospital Rome, Italy. all admitted between 2015 and 2018, who received mg loading...
BACKGROUND Arterial hypotension during major surgery is related to postoperative complications and mortality. Both fluids vasopressors increase blood pressure (BP) by inducing different physiological response. We devised a protocol which relies on dynamic arterial elastance (Ea dyn ) guide BP optimisation abdominal surgery, tested its effectiveness tissue perfusion. OBJECTIVE explore if an Ea -based could affect lactate levels, fluid administration, clinical complications. DESIGN randomised...
Abstract Background Long-term outcomes of patients treated with helmet noninvasive ventilation (NIV) are unknown: safety concerns regarding the risk patient self-inflicted lung injury and delayed intubation exist when NIV is applied in hypoxemic patients. We assessed 6-month outcome who received or high-flow nasal oxygen for COVID-19 respiratory failure. Methods In this prespecified analysis a randomized trial versus (HENIVOT), clinical status, physical performance (6-min-walking-test 30-s...
To explore the association between endotoxin activity (EA) and septic cardiomyopathy (SCM), relationship removal by Polymyxin-B hemoperfusion (PMX-HP) recovery from SCM (R-SCM), correlation R-SCM 28-day mortality in patients admitted to intensive care unit (ICU).Observational study that included two ICUs of a tertiary university hospital April 2011 December 2019, who received PMX-HP for sepsis/septic shock. The were assessed transthoracic echocardiography.Among 148 patients, was diagnosed 60...
Abstract Background In critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We investigated plasmatic and pulmonary concentrations HD TGC in treatment severe infections. Methods This was a single centre, prospective, observational study that conducted twenty-bed mixed ICU 1,500- bed teaching hospital Rome, Italy. all patients admitted to between 2015 2018, who...