Alessandro Giani
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Surgical Treatments
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Gastric Cancer Management and Outcomes
- Nutrition and Health in Aging
- Colorectal Cancer Screening and Detection
- Pancreatitis Pathology and Treatment
- Liver Disease and Transplantation
- Frailty in Older Adults
- Renal cell carcinoma treatment
- COVID-19 and healthcare impacts
- Abdominal Surgery and Complications
- Intensive Care Unit Cognitive Disorders
- Hip and Femur Fractures
- Enhanced Recovery After Surgery
- Esophageal and GI Pathology
- Hernia repair and management
- Body Composition Measurement Techniques
- Appendicitis Diagnosis and Management
- Colorectal and Anal Carcinomas
- Cancer Genomics and Diagnostics
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2020-2025
Ospedale Maggiore
2020-2024
Institute Mutualiste Montsouris
2024
University of Milano-Bicocca
2017-2023
Sapienza University of Rome
2023
Fondazione Poliambulanza Istituto Ospedaliero
2022
ORCID
2021-2022
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2021-2022
Azienda Ospedaliera San Gerardo
2017-2021
Universidad Gerardo Barrios
2014-2015
Objective: To develop and update evidence- consensus-based guidelines on laparoscopic robotic pancreatic surgery. Summary Background Data: Minimally invasive surgery (MIPS), including surgery, is complex technically demanding. Minimizing the risk for patients requires stringent, evidence-based guidelines. Since International Miami Guidelines MIPS in 2019, new developments key publications have been reported, necessitating an update. Methods: Evidence-based 22 topics 8 domains were proposed:...
Abstract Background Accurate quality of life (QoL) data and functional results after cancer surgery are lacking for older patients. The international, multicenter Geriatric Oncology Surgical Assessment Functional rEcovery Surgery (GOSAFE) Study compares QoL before identifies predictors decline in QoL. Methods GOSAFE prospectively collected major elective on adults (≥70 years). Frailty assessment was performed postoperative outcomes recorded (30, 90, 180 days postoperatively) together with by...
The GOSAFE study evaluates risk factors for failing to achieve good quality of life (QoL) and functional recovery (FR) in older patients undergoing surgery colon rectal cancer.
Background: We aimed to assess the ability of comprehensive complication index (CCI) and Clavien-Dindo (CDC) scale predict excessive length hospital stay (e-LOS) in patients undergoing liver resection for hepatocellular carcinoma. Methods: Patients were identified from an Italian multi-institutional database randomly selected be included either a derivation or validation set. Multivariate logistic regression models ROC curve analysis including CCI CDC as predictors e-LOS fitted compare...
Clear indications on how to select retreatments for recurrent hepatocellular carcinoma (HCC) are still lacking.To create a machine learning predictive model of survival after HCC recurrence allocate patients their best potential treatment.Real-life data were obtained from an Italian registry between January 2008 and December 2019 median (IQR) follow-up 27 (12-51) months. External validation was made derived by another cohort Japanese cohort. Patients who experienced first surgical approach...
Abstract Background Benchmarking is the process to used assess best achievable results and compare outcomes with that standard. This study aimed in minimally invasive distal pancreatectomy splenectomy (MIDPS). Methods retrospective included consecutive patients undergoing MIDPS for any indication, between 2003 2019, 31 European centres. Benchmarks of main clinical were calculated according Achievable Benchmark Care (ABC™) method. After identifying independent risk factors severe morbidity...
Abstract Background Standard lymphadenectomy for pancreatoduodenectomy is defined pancreatic ductal adenocarcinoma and adopted patients with non-pancreatic periampullary cancer (NPPC), ampullary (AAC), distal cholangiocarcinoma (dCCA), or duodenal (DAC). This study aimed to compare the patterns of lymph node metastases among different NPPCs in a large series systematic review guide discussion on surgical pathology assessment. Methods retrospective cohort included after NPPC at least one...
To assess the association between neoadjuvant therapy and overall survival (OS) in patients with left-sided resectable pancreatic cancer (RPC) compared to upfront surgery. Left-sided is associated worse OS right-sided cancer. Although currently seen as not effective RPC, current randomized trials included mostly RPC. International multicenter retrospective study including consecutive after resection for pathology-proven either or surgery 76 centers from 18 countries on 4 continents...
Abstract Aim Despite the suggested potential benefit of complete mesocolic excision (CME) for right‐sided colon cancer (RCC) patient survival, concerns about its safety and feasibility have contributed to delayed acceptance procedure, especially when performed by a minimally invasive approach. Thus, aim this work was evaluate actual learning curve (LC) laparoscopic CME experienced colorectal surgeons. Method Prospectively collected data consecutive patients undergoing RCC between October...
Abstract Background Benchmarking is an important tool for quality comparison and improvement. However, no benchmark values are available minimally invasive spleen-preserving distal pancreatectomy, either laparoscopically or robotically assisted. The aim of this study was to establish benchmarks these techniques using two different methods. Methods Data from patients undergoing assisted pancreatectomy were extracted a multicentre database (2006–2019). Benchmarks 10 outcomes calculated the...
To evaluate whether perioperative bioimpedance vector analysis (BIVA) predicts the occurrence of surgery-related morbidity.BIVA is a reliable tool to assess hydration status and compartimentalized fluid distribution.The BIVA patients undergoing resection for pancreatic malignancies was prospectively measured on day prior surgery postoperative (POD)1. Postoperative morbidity scored per Clavien-Dindo classification (CDC), Comprehensive Complication Index (CCI).Out 249 patients, overall major...
This study aimed to compare surgical and oncological outcomes after minimally invasive pancreatoduodenectomy (MIPD) versus open (OPD) for distal cholangiocarcinoma (dCCA).
Abstract COVID-19 negatively affected surgical activity, but the potential benefits resulting from adopted measures remain unclear. The aim of this study was to evaluate change in activity and benefit perspective Italian surgeons on behalf SPIGC. A nationwide online survey practice before, during, after pandemic conducted March–April 2022 (NCT:05323851). Effects hospital-related patients’ management personal professional development across specialties were explored. Data demographics,...