Pasquale Perri
A5021898630- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Virus-based gene therapy research
- Breast Cancer Treatment Studies
- Cutaneous Melanoma Detection and Management
- Sarcoma Diagnosis and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- Glycosylation and Glycoproteins Research
- Ovarian cancer diagnosis and treatment
- Metastasis and carcinoma case studies
- Colorectal Cancer Surgical Treatments
- Cancer Treatment and Pharmacology
- HER2/EGFR in Cancer Research
- Neuroendocrine Tumor Research Advances
- Colorectal and Anal Carcinomas
- Lung Cancer Research Studies
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Ultrasound and Hyperthermia Applications
- Monoclonal and Polyclonal Antibodies Research
- Neuroblastoma Research and Treatments
- Pancreatic and Hepatic Oncology Research
- Viral Infectious Diseases and Gene Expression in Insects
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2024
University of Florence
2024
National Cancer Institute
2010
Tumori Foundation
1991-2009
Instituto Nazionale Tumori Regina Elena
1991-2009
Breast Center
2009
Universitair Ziekenhuis Leuven
2009
National Institutes of Health
2001
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
1996
Background: We aimed to assess the ability of comprehensive complication index (CCI) and Clavien-Dindo (CDC) scale predict excessive length hospital stay (e-LOS) in patients undergoing liver resection for hepatocellular carcinoma. Methods: Patients were identified from an Italian multi-institutional database randomly selected be included either a derivation or validation set. Multivariate logistic regression models ROC curve analysis including CCI CDC as predictors e-LOS fitted compare...
Clear indications on how to select retreatments for recurrent hepatocellular carcinoma (HCC) are still lacking.To create a machine learning predictive model of survival after HCC recurrence allocate patients their best potential treatment.Real-life data were obtained from an Italian registry between January 2008 and December 2019 median (IQR) follow-up 27 (12-51) months. External validation was made derived by another cohort Japanese cohort. Patients who experienced first surgical approach...
Gallbladder cancer (GBC) is an aggressive malignancy with poor prognosis. Due to the generally asymptomatic course of disease in its early stages, patients are most often diagnosed incidentally (iGBC), following cholecystectomy for presumed benign disease. Thorough staging predict oncologic and technical resectability mandatory. Robotic surgery has emerged as a promising approach treatment complex hepatic malignancies, it can be performed almost all types liver resections. However, due...
Low-grade malignant tumors arise in the abdomen, do not infiltrate, and "redistribute" on peritoneum with no extraregional spreading. In these cases, aggressive surgery combined localized chemotherapy may provide cure.After removing tumor regional en bloc, intraabdominal hyperthermic chemoperfusion was performed throughout abdominopelvic cavity. Alternatively, early chemotherapy, starting first postoperative day, administered for 5 days.Forty patients affected extensive peritoneal...
The majority of gastroenteropancreatic well-differentiated endocrine carcinomas (WDEC) express somatostatin receptors (SSTR). To correlate the expression SSTR subtypes by reverse transcriptase-polymerase chain reaction (RT-PCR) with clinicopathological features and survival in a group WDEC patients, 42 tissue specimens from 33 patients were analysed. All treated analogues had median follow-up period 45 months (range 6-196). Neither SSTR2 SSTR5 nor Ki-67 level alone correlated survival. A...
Eighty-two patients diagnosed with gastrointestinal (GI) adenocarcinoma were evaluated before and for 26 months after primary tumor resection the presence of two serum markers: tumor-associated glycoprotein-72 (TAG-72) carcinoembryonic antigen (CEA). Elevated TAG-72 CEA levels found preoperatively in 32 (39%) 34 (41.5%) 82 patients, respectively. The percentage elevated either or was 56.1% (46 82). Twelve (15%) who had normal levels, conversely, from 14 (17%) negative positive. Forty-five...
To evaluate activity and tolerability of two anthracycline-containing regimens as first-line treatment for anthracycline-naïve relapsed breast cancer patients. Patients with not previously treated adjuvant anthracyclines were randomly assigned to epirubicin/vinorelbine (arm A: EPI/VNB, EPI 90 mg/m2 on day 1, VNB 25 days 1,5 plus G-CSF subcutaneously 7-12, cycles repeated every 21 days), or pegylated liposomal doxorubicin/VNB B: PLD/VNB, PLD 40 30 15, 4 weeks). Primary objective was the...
Objective: To evaluate the effect of a liver transplantation (LT) program on outcomes resectable hepatocellular carcinoma (HCC). Background: Surgical treatment HCC includes both hepatic resection (HR) and LT. However, presence cirrhosis possibility recurrence make management this disease complex probably different according to LT program. Methods: Patients undergoing HR for between January 2005 December 2019 were identified from national database HCC. The main study major surgical...