A5060836815- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Gout, Hyperuricemia, Uric Acid
- Advanced X-ray and CT Imaging
- Respiratory Support and Mechanisms
- Cardiac Imaging and Diagnostics
- Orthopedic Surgery and Rehabilitation
- Intensive Care Unit Cognitive Disorders
- Peripheral Nerve Disorders
- Shoulder Injury and Treatment
- Hemoglobinopathies and Related Disorders
- Psychosomatic Disorders and Their Treatments
- Nerve Injury and Rehabilitation
- COVID-19 and Mental Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sports injuries and prevention
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Case Reports on Hematomas
- Erythropoietin and Anemia Treatment
- Soft Robotics and Applications
- Heme Oxygenase-1 and Carbon Monoxide
- Alcohol Consumption and Health Effects
- Osteomyelitis and Bone Disorders Research
- Surgical Simulation and Training
- Myofascial pain diagnosis and treatment
Innsbruck Medical University
2019-2025
Universität Innsbruck
2019-2024
Background After the 2002/2003 severe acute respiratory syndrome outbreak, 30% of survivors exhibited persisting structural pulmonary abnormalities. The long-term sequelae coronavirus disease 2019 (COVID-19) are yet unknown, and comprehensive clinical follow-up data lacking. Methods In this prospective, multicentre, observational study, we systematically evaluated cardiopulmonary damage in subjects recovering from COVID-19 at 60 100 days after confirmed diagnosis. We conducted a detailed...
Severe coronavirus disease 2019 (COVID-19) is frequently associated with hyperinflammation and hyperferritinemia. The latter related to increased mortality in COVID-19. Still, it not clear if iron dysmetabolism mechanistically linked COVID-19 pathobiology.We herein present data from the ongoing prospective, multicentre, observational CovILD cohort study (ClinicalTrials.gov number, NCT04416100), which systematically follows up patients after 109 participants were evaluated 60 days onset of...
Background The long-term pulmonary sequelae of COVID-19 is not well known. Purpose To characterize patterns and rates improvement chest CT abnormalities 1 year after pneumonia. Materials Methods This was a secondary analysis prospective, multicenter observational cohort study conducted from April 29 to August 12, 2020, assess at approximately 2, 3, 6 months onset symptoms. Pulmonary findings were graded for each lung lobe using qualitative severity score (CTSS) ranging 0 (normal) 25 (all...
Background: The optimal procedures to prevent, identify, monitor, and treat long-term pulmonary sequelae of COVID-19 are elusive. Here, we characterized the kinetics respiratory symptom recovery following COVID-19. Methods: We conducted a longitudinal, multicenter observational study in ambulatory hospitalized patients recruited early 2020 (n = 145). Pulmonary computed tomography (CT) lung function (LF) readouts, prevalence, clinical laboratory parameters were collected during acute at 60,...
Recovery trajectories from coronavirus disease 2019 (COVID-19) call for longitudinal investigation. We aimed to characterise the kinetics and status of clinical, cardiopulmonary mental health recovery up 1 year following COVID-19.Clinical evaluation, lung function testing (LFT), chest computed tomography (CT) transthoracic echocardiography were conducted at 2, 3, 6 12 months after onset. Submaximal exercise capacity, quality life assessed months. patterns investigated by mixed-effect...
Coronavirus disease 2019 (COVID-19) is frequently associated with iron dyshomeostasis. The latter related to acute severity and COVID-19 convalescence. We herein describe dyshomeostasis at follow-up its association long-term pulmonary symptomatic recovery. prospective, multicentre, observational cohort study "Development of Interstitial Lung Disease (ILD) in Patients With Severe SARS-CoV-2 Infection (CovILD)" encompasses serial extensive clinical, laboratory, functional imaging evaluations...
Nerve entrapment syndromes are commonly encountered in clinical practice. Accurate diagnosis and management require a knowledge of peripheral neuroanatomy the recognition key symptoms findings. frequently associated with structural abnormalities affected nerve. Therefore, imaging allows evaluation cause, severity, etiology entrapment. High-resolution ultrasonography can depict early chronic morphological changes within entire nerve course is therefore an ideal modality for diagnosing various...
To determine the association of cardiovascular atherosclerotic plaque monosodium urate deposits with occurrence major events in gout and hyperuricemia patients.
To assess the association between neoadjuvant therapy and overall survival (OS) in patients with left-sided resectable pancreatic cancer (RPC) compared to upfront surgery. Left-sided is associated worse OS right-sided cancer. Although currently seen as not effective RPC, current randomized trials included mostly RPC. International multicenter retrospective study including consecutive after resection for pathology-proven either or surgery 76 centers from 18 countries on 4 continents...
Objectives: Prediction of lung function deficits following pulmonary infection is challenging and suffers from inaccuracy. We sought to develop machine-learning models for prediction post-inflammatory changes based on COVID-19 recovery data. Methods: In the prospective CovILD study (n = 420 longitudinal observations n 140 survivors), data testing (LFT), chest CT including severity scoring by a human radiologist density measurement artificial intelligence, demography, persistent symptoms were...
Monosodium uric acid (MSU) crystals may accumulate in the coronary plaque. The objective was to assess whether dual-energy computed tomography (DECT) allows for detection of MSU plaque.Patients were examined with 128-slice DECT applying a cardiac electrocardiogram-gated and peripheral extremity protocol. Patients divided into 3 groups: gout (tophi >1 cm joints), hyperuricemia (>6.5 mg/dL serum acid), controls. groups matched cardiovascular risk factors. acid-positive (+) calcified plaque...
Background: The purpose of this study was to evaluate plantar fasciae healthy subjects and patients with fasciitis by shear wave velocity (SWV) stiffness correlation B-Mode color Doppler ultrasonography (CDUS) establish cut-off values. Methods: This observational conducted the approval Institutional Review Boards (IRBs) our institution. 108 unilateral were evaluated including 87 consecutive (mean age 51.7; range: 29–82) (66 women 21 men) asymptomatic matched volunteers 47.3; 32–58) (15 6...
Ultrasonography (renamed from the Journal of Korean Society Ultrasound in Medicine January 2014), official English-language journal (KSUM), is an international peer-reviewed academic dedicated to practice, research, technology, and education dealing with medical ultrasound, Aims Scope:Ultrasonography ultrasound.It published four times per year: 1, April July October 1. Original articles, topical reviews, pictorial essays, notable case reports are covering state-of-the-art content. also...
Background: Robotic-based guidance systems are becoming increasingly capable of assisting in needle placement during interventional procedures. Despite these technical advances, less sophisticated low-cost devices promise to enhance puncture accuracy compared with the traditional freehand technique. Purpose: To compare vitro and feasibility two different aiming for computed-tomography (CT)-guided punctures. Methods: A total 560 CT-guided punctures were performed by using either a robotic...
Dual-energy computed tomography (DECT) allows direct visualization of monosodium urate (MSU) deposits in joints and soft tissues.To describe the distribution MSU cadavers using DECT head, body trunk, feet.A total 49 (41 embalmed 8 fresh cadavers; 20 male, 29 female; mean age, 79.5 years; SD ± 11.3; range 52-95) unknown clinical history underwent to assess feet. Lens, thoracic aorta, foot tendon dissections were used verify by polarizing light microscopy.33/41 (80.5%) showed within aorta....
To evaluate two different dual-energy computed tomography (DECT) post-processing protocols for the detection of MSU deposits in foot tendons cadavers with verification by polarizing light microscopy as gold standard.A total 40 embalmed (15 male; 25 female; median age, 82 years; mean, 80 range, 52-99; SD ± 10.9) underwent DECT to assess tendons. Two postprocessing Hounsfield unit (HU) thresholds, 150/500 (=established) versus 120/500 (=modified). HU were applied dual source acquisition kV...
The CovILD study is a prospective, multicenter, observational cohort to systematically follow up patients after coronavirus disease-2019 (COVID-19). We extensively evaluated 145 COVID-19 at 3 follow-up visits scheduled for 60, 100, and 180 days initial confirmed diagnosis based on typical symptoms positive reverse transcription-polymerase chain reaction (RT-PCR) severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). employed comprehensive pulmonary function laboratory tests, including...
Background: Iliotibial band syndrome (ITBS) represents one of the most common running related injuries. The pathophysiology is postulated to be caused by excessive ITB tension, impingement and irritation soft tissues at lateral femoral epicondyle. However, direct evidence has yet found multifactorial etiology under discussion. purpose was evaluate stiffness ITB, gluteus maximus (GM) tensor fasciae latae (TFL) muscles using shear wave elastography (SWE). Methods: In 14 patients with...
Injection therapies play an increasingly decisive role in the treatment of lower back pain. Cumulative studies could show benefits ultrasound-guided instillation procedures cervical and lumbar spine. We conducted this study to provide a new simple sonographic approach for pararadicular injections sacral spinal nerves prove feasibility accuracy by means CT anatomic dissection.Eight at four different levels spine on human ethanol-glycerol-embalmed cadaver (S1-S4) were performed. By sonography...
Objective: To evaluate two different DECT postprocessing protocols for detection of MSU deposits in foot tendons cadavers with verification by polarizing light microscopy as gold standard.Material and Methods: A total 40 embalmed (15 male; 25 female; median age, 82 years; mean, 80 range, 52 - 99; SD ± 10.9) underwent to assess tendons.Two Hounsfield unit (HU) thresholds 150/500 (=established) versus 120/500 (= modified) HU were applied dual source acquisition kV tube 140 B.Six...
Abstract Background COVID-19 is associated with long-term pulmonary symptoms and may result in chronic impairment. The optimal procedures to prevent, identify, monitor, treat these sequelae are elusive. Research question To characterize the kinetics of recovery, risk factors constellations clinical features linked persisting radiological lung findings after COVID-19. Study design methods A longitudinal, prospective, multicenter, observational cohort study including patients (n = 108)....
<h3>Background:</h3> Recently, monosodium urate (MSU) deposits were demonstrated in coronary arteries of 86.4% gout patients by dual energy computed tomography (DECT).[1] Cardiovascular (CV) MSU associated with major adverse cardiac events (MACE) [2], but also the presence peripheral increased risk for CV disease and death.[3] <h3>Objectives:</h3> The aim this retrospective analysis was to evaluate possible association 1) 2) MACE. <h3>Methods:</h3> We included all patients, recruited at...