A5074776782- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Particle physics theoretical and experimental studies
- Cardiac pacing and defibrillation studies
- ECG Monitoring and Analysis
- Particle Detector Development and Performance
- High-Energy Particle Collisions Research
- Advanced MRI Techniques and Applications
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Electronic Health Records Systems
- Metabolomics and Mass Spectrometry Studies
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Medication Adherence and Compliance
- Cardiac Imaging and Diagnostics
- Neurological disorders and treatments
- Quantum Chromodynamics and Particle Interactions
- Iron Metabolism and Disorders
- Advanced Proteomics Techniques and Applications
- Data Quality and Management
- Chronic Disease Management Strategies
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Gene expression and cancer classification
UMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik
2011-2025
Tirol Kliniken
2019-2024
Universidade de Caxias do Sul
2024
Innsbruck Medical University
2008-2023
Universität Innsbruck
2023
Austrian Institute of Technology
2019-2021
University of Applied Sciences Tyrol
2004-2021
University of Freiburg
2008-2020
Zurich Heart House
2020
Humboldt State University
2015
Introduction Prescription patterns of antidiabetic drugs in the period from 2012 to 2018 were investigated based on Diabetes Registry Tyrol. To validate findings, we compared numbers with trends different national registries conducted a comparable time. Research design and methods Medication data, prescription patterns, age groups, therapies quality parameters (hemoglobin A1c, body mass index, complications) 10 875 patients type 2 diabetes retrospectively assessed descriptively analyzed. The...
Recovery trajectories from coronavirus disease 2019 (COVID-19) call for longitudinal investigation. We aimed to characterise the kinetics and status of clinical, cardiopulmonary mental health recovery up 1 year following COVID-19.Clinical evaluation, lung function testing (LFT), chest computed tomography (CT) transthoracic echocardiography were conducted at 2, 3, 6 12 months after onset. Submaximal exercise capacity, quality life assessed months. patterns investigated by mixed-effect...
Abstract Background and Aims Haemochromatosis is characterized by progressive iron overload affecting the liver can cause cirrhosis hepatocellular carcinoma. Most haemochromatosis patients are homozygous for p.C282Y in HFE , but only a minority of individuals with this genotype will develop disease. The aim was to assess penetrance overload, fibrosis, carcinoma life expectancy. Methods A total 8839 from Austrian region Tyrol were genotyped variant between 1997 2021. Demographic, laboratory...
Background: To provide updated estimates on SARS-CoV-2 antibody seroprevalence and average titres for Central Europe. Methods: In repeat cross-sectional investigations (1 May 2022 to 9 March 2023) involving 28,768 blood donors in the Federal State of Tyrol, Austria (participation rate: 87.0%), we measured Spike receptor-binding domain (RBD) Nucleocapsid IgG antibodies (37,065 12,645 samples), estimated monthly seroprevalences geometric mean titres. Results: Median age participants was 45.4...
Abstract Motivation: Alcoholic fatty liver disease (AFLD) and non-AFLD (NAFLD) can progress to severe diseases such as steatohepatitis, cirrhosis cancer. Thus, the detection of early is essential; however, minimal invasive diagnostic methods in clinical hepatology still lack specificity. Results: Ion molecule reaction mass spectrometry (IMR-MS) was applied a total 126 human breath gas samples comprising 91 cases (AFLD, NAFLD cirrhosis) 35 healthy controls. A new feature selection modality...
Abstract Motivation: Prostate cancer is the most prevalent tumor in males and its incidence expected to increase as population ages. treatable by excision if detected at an early enough stage. The challenges of diagnosis require discovery novel biomarkers tools for prostate management. Results: We developed a feature selection algorithm termed associative voting (AV) identifying biomarker candidates data measured via targeted metabolite profiling MS/MS analysis. benchmarked our against two...
There is uncertainty about the seroprevalence of anti-SARS-CoV-2 antibodies in general population Austria and waning over time. We conducted a seroepidemiological study between June 2020 September 2021, enrolling blood donors aged 18–70 years across Tyrol, (participation rate: 84.0%). analyzed serum samples for against spike or nucleocapsid proteins SARS-CoV-2. performed total 47,363 taken from 35,193 individuals (median age, 43.1 (IQR: 29.3–53.7); 45.3% women; 10.0% with prior SARS-CoV-2...
ABSTRACT Using continuous thoracic impedance measurements, sleep apnea can be long‐time monitored via an electronic device sensor. In the ACaSA trial, 233 patients implanted with a cardiac pacemaker (MicroPort CRM, Clamart, France) were prospectively observed between March 2022 and July 2024. For each night of follow‐up, burden device‐detected (DDSA) was measured transthoracic impedance, defined by respiratory disturbance index (RDI) ≥ 20 events per sleeping hour. Local meteorological data...
Background Little is known about the effect of cardiac resynchronization therapy (CRT) on endo- and epicardial ventricular activation. Noninvasive imaging electrophysiology (NICE) a novel tool for visualization both epi- endocardial electrical Methodology/Principal Findings NICE was performed in ten patients with congestive heart failure (CHF) undergoing CRT without structural disease (control group). fusion data from high-resolution ECG mapping model patient's individual cardiothoracic...
Abstract Wastewater-based epidemiology (WBE) is an effective approach for tracking information on spatial distribution and temporal trends of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the community level. Herein, development, implementation, operation wastewater monitoring program serving Tyrol – a federal province Austria are described. The development this was initiated by Tyrolean health authorities end first phase Coronavirus disease 2019 (COVID-19) pandemic (May...
Olfactory dysfunction (OD) commonly accompanies coronavirus disease 2019 (COVID-19). We investigated the kinetics of OD resolution following SARS-CoV-2 infection (wild-type and alpha variant) its impact on quality life, physical mental health.OD prevalence was assessed in an ambulatory COVID-19 survey (n = 906, ≥ 90 days follow-up) observational cohort hospitalized individuals 108, 360 follow-up). Co-occurrence with other symptoms effects health were analyzed by multi-dimensional scaling,...
Abstract Motivation: The discovery of new and unexpected biomarkers in cardiovascular disease is a highly data-driven process that requires the complementary power modern metabolite profiling technologies, bioinformatics biostatistics. Clinical early myocardial injury are lacking. A prospective biomarker cohort study was carried out to identify, categorize profile kinetic patterns metabolic planned infarction (PMI) spontaneous (SMI) infarction. We applied targeted mass spectrometry...
Objective: In this synopsis, the editors of Clinical Information Systems (CIS) section IMIA Yearbook Medical Informatics overview recent research and propose a selection best papers published in 2022 CIS field. Methods: The follow systematic approach to gather relevant articles select for section. This year, they updated query incorporate topic telemedicine removed search terms related geographic information systems. revised resulted larger number identified papers, necessitating appointment...
In this paper, a cellular automaton framework for processing the spatiotemporal spread of infectious diseases is presented. The developed environment simulates and visualizes how might spread, hence provides powerful instrument health care organizations to generate disease prevention contingency plans. study, outbreak an avian flu like virus was modeled in state Tyrol, various scenarios such as quarantine, effect different medications on viral changes social behavior were simulated.
Introduction The potential for secondary use of health data to improve healthcare is currently not fully exploited. Health largely kept in isolated silos and key infrastructure aggregate these into standardized bodies knowledge underdeveloped. We describe the development, implementation, evaluation a federated facilitate versatile based on Data Space nodes. Materials methods Our proposed nodes are self-contained units that digest through an extract-transform-load framework pseudonymizes...
Ketogenic dietary therapies (KDT) are diets that induce a metabolic condition comparable to fasting. All types of KDT comprise reduction in carbohydrates whilst fat is increased up 90% daily energy expenditure. The amount protein normal or slightly increased. effective, well studied and established as non-pharmacological treatments for pediatric patients with refractory epilepsy specific inherited diseases such Glucose Transporter Type 1 Deficiency Syndrome. Patients caregivers have...
This study scrutinizes free AI tools tailored for supporting literature review and analysis in academic research, emphasizing their response to direct inquiries. Through a targeted keyword search, we cataloged relevant evaluated output variation source validity. Our results reveal spectrum of qualities, with some integrating non-academic sources others depending on outdated information. Notably, most showed lack transparency selection. highlights two key limitations: the exclusion commercial...
Background: Despite being the most commonly performed valvular intervention, risk prediction for aortic valve replacement in patients with severe stenosis by currently used scores remains challenging. The study aim was to develop a biomarker-based score means of neuronal network. Methods: In this multicenter study, 3595 were divided into test and validation cohorts (70% 30%) random allocation. Input variables ABC-AS age, cardiac biomarker high-sensitivity troponin T, patient history...
The aim of this study was to quantify the effect cardiac anisotropy in activation-based inverse problem electrocardiography. Differences patterns simulated body surface potential maps for isotropic and anisotropic conditions were investigated with regard activation time (AT) imaging ventricular depolarization. AT estimated by solving nonlinear ill-posed employing spatio-temporal regularization. Four different reference (sinus rhythm, right-ventricular septal pacing, accessory pathway)...
Because a large proportion of the Austrian population has been infected with SARS-CoV-2 during high incidence periods in winter 2021/2022, up-to-date estimates seroprevalence anti-SARS-CoV-2 antibodies are required to inform upcoming public health policies. We quantified anti-Spike IgG antibody levels 22,607 individuals that donated blood between October 2021 and April 2022 across Tyrol, Austria (participation rate: 96.0%). Median age participants was 45.3 years (IQR: 30.9−55.1); 41.9% were...
Summary Objectives: To review recent research efforts in the field of ubiquitous computing health care. identify current trends and further challenges for medical informatics. Methods: Analysis contents Yearbook on Medical Informatics 2005 International Association (IMIA). Results: The includes 34 original papers selected from 22 peer-reviewed scientific journals related to several distinct areas: clinical management, patient records, information systems, signal processing biomedical...