A5031384782- Prostate Cancer Treatment and Research
- Physics and Engineering Research Articles
- Corporate Governance and Management
- Prostate Cancer Diagnosis and Treatment
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Flexible and Reconfigurable Manufacturing Systems
- Law and Political Science
- Civil and Structural Engineering Research
- Emergency and Acute Care Studies
- Electrolyte and hormonal disorders
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Hemoglobinopathies and Related Disorders
- Genomic variations and chromosomal abnormalities
- Bladder and Urothelial Cancer Treatments
- Heart Failure Treatment and Management
- Digital Innovation in Industries
- Venous Thromboembolism Diagnosis and Management
- Public Administration and Political Analysis
- High Altitude and Hypoxia
- Medical and Health Sciences Research
- Iron Metabolism and Disorders
- German Social Sciences and History
- Chronic Obstructive Pulmonary Disease (COPD) Research
FH Campus Wien
2023-2025
Tirol Kliniken
2024
Roche Pharma AG (Germany)
2009-2024
Private University in the Principality of Liechtenstein
2021-2024
Attocube Systems (Germany)
2024
University of Applied Sciences Tyrol
2024
University of Bayreuth
2022
Simula Research Laboratory
2022
University of Oslo
2022
Kantonsspital Aarau
2011-2021
Several trials evaluating the effect of prostate-specific antigen (PSA) testing on prostate-cancer mortality have shown conflicting results. We updated in European Randomized Study Screening for Prostate Cancer with 2 additional years follow-up.
Glucagon-like peptide-1-(7–36)-amide (GLP-1) is involved in satiety control and glucose homeostasis. Animal studies suggest a physiological role for GLP-1 water salt This study's aim was to define the effects of on sodium excretion both healthy obese men. Fifteen subjects 16 men (mean body mass index, 36 kg/m2) were examined double-blind, placebo-controlled, crossover study demonstrate 3-h infusion urinary excretion, output, glomerular filtration rate after an iv 9.9-g load. Infusion evoked...
Cystatin C is a nonglycosylated basic protein (13.36 kDa) and can be found in variety of biologic fluids (1). serum concentration not influenced by gender, inflammation, or lean tissue mass regarded to mainly determined glomerular filtration rate (GFR) (2)(3)(4)(5). has been described as meeting many the characteristics an ideal GFR marker (e.g., endogenously produced at constant rate, freely filtered glomerulus, neither reabsorbed nor secreted renal tubule, extrarenally eliminated) reported...
CSF is thought to flow continuously from the site of production in ventricles into interconnected spaces; i.e. cisterns and subarachnoid spaces (SASs). Since SAS optic nerve defined by a cul-de-sac anatomy, it not evident how local might recycle that region general SAS. The concept free communication has recently been challenged description concentration gradient beta-trace protein, lipocalin-like prostaglandin d-synthase (L-PGDS), between spinal nerve, indicating diminished clearance or...
Abstract BACKGROUND Cerebrospinal fluid (CSF) amyloid-β (Aβ42) is a well-established biomarker for Alzheimer disease. Several immunoassays Aβ42 exist but differ in absolute concentrations and may suffer from matrix interference, thereby hampering interlaboratory comparisons the use of general cutoff levels. Together with IFCC Working Group on CSF Proteins, we developed candidate reference measurement procedure (RMP) Aβ42. METHODS The antibody-independent RMP was based solid-phase extraction...
Abstract Introduction Early risk stratification in the emergency department (ED) is vital to reduce time effective treatment high-risk patients and improve patient flow. Yet, there a lack of investigations evaluating incremental usefulness multiple biomarkers measured upon admission from distinct biological pathways for predicting fatal outcome high initial urgency unselected ED multicenter multinational setting. Method We included consecutive, adult, medical seeking care into this...
<b><i>Background and Aims:</i></b> Malnutrition is associated with poor clinical outcomes. Whether there a causal relationship or it merely mirrors severe patient condition remains unclear. We examined the association of malnutrition biomarkers characteristic different pathophysiological states to better understand underlying etiological mechanisms. <b><i>Methods:</i></b> prospectively followed consecutive adult medical inpatients....
Assessment of renal function in patients with transplants is great importance. Various studies have reported cystatin C as an easily and rapidly assessable marker that can be used for accurate information on impairment. To date, no study available to define the role transplants.Thirty steady-state (50% male/50% female) status post-kidney transplantation were studied. assess function, C, creatinine clearance, serum creatinine, beta2-microglobulin (beta2M), [125I]iothalamate clearance...
Cerebrospinal fluid (CSF) pressure and composition are generally thought to be homogeneous within small limits throughout all CSF compartments. sampled during lumbar puncture therefore should representative for On the basis of clinical findings, histology biochemical markers, we present first time strong evidence that subarachnoid spaces (SAS) optic nerve (ON) can become separated from other compartments in certain ON disorders, thus leading an sheath compartment syndrome. This may result...
In previous studies with glucagon-like peptide-1 (GLP-1) we have observed that this peptide modulates fluid intake and increases renal sodium excretion in healthy volunteers patients diabetes mellitus type 2. The effect of GLP-1 on thirst, water osmoregulation has, however, not been examined detail humans. <i>Methods:</i> Seventeen male subjects were enrolled two double-blind, placebo-controlled studies. study part A, 8 participated a protocol an intravenous salt load 26.7 ± 0.9...
Only a small proportion of blood cultures routinely performed in emergency department (ED) patients is positive. Multiple clinical scores and biomarkers have previously been examined for their ability to predict bacteremia. Conclusive validation these essential. This observational cohort study included with suspected infection who had culture sampling at ED admission. We assessed 5 admission concentrations procalcitonin (PCT), C-reactive protein (CRP), lymphocyte white cell counts, the...
Copeptin is a stable surrogate marker of vasopressin release; the peptides are stoichiometrically secreted from neurohypophysis due to elevated plasma osmolality or nonosmotic stress. We hypothesized that following stress pituitary surgery, patients with neurohypophyseal damage and eventual diabetes insipidus (DI) would not exhibit expected pronounced copeptin elevation.The objective was evaluate copeptin's accuracy predict DI surgery.This prospective multicenter observational cohort...
Objectives To assess symptoms and characteristics of hyponatremia, the most common electrolyte disturbance in hospitalized individuals a condition that is associated with substantial morbidity mortality. Design Prospective observational multicenter study. Setting Two Swiss academic centers. Participants Individuals profound hypoosmolar hyponatremia (sodium <125 mmol/L) (N = 298). Measurements All complete medical history including current medications, therapy management, in‐hospital...
Purpose To investigate the aqueous humor proteome in patients with glaucoma and a control group. Method Aqueous was obtained from five human donors diagnosed primary open angle (POAG) age- sex-matched controls undergoing cataract surgery. Quantitative analysis of by hyper reaction monitoring mass spectrometry (HRM-MS) based on SWATH technology performed. Results Expression levels 87 proteins were found to be different between glaucomatous humor. Of proteins, 34 significantly upregulated,...
Hyponatraemia is common and its differential diagnosis challenging. Commonly used diagnostic algorithms have limited accuracy. Copeptin, the c-terminal portion of precursor peptide arginine vasopressin might help in hyponatraemia.Prospective multicentre observational study.A total 298 patients admitted with profound hypoosmolar hyponatraemia (Na < 125 mmol/l) were evaluated. Three experts uninvolved patients' care determined aetiology after standardized evaluation.Hyponatraemia diagnoses as...
Coronavirus Disease-19 (COVID-19) convalescents are at risk of developing a de novo mental health disorder or worsening pre-existing one. COVID-19 outpatients have been less well characterized than their hospitalized counterparts. The objectives our study were to identify indicators for poor following outpatient management and high-risk individuals.We conducted binational online survey with adult non-hospitalized (Austria/AT: n = 1,157, Italy/IT: 893). Primary endpoints positive screening...
Background. Heparin-induced thrombocytopenia (HIT), a well-known side effect of heparin therapy, occurs in 1% to 5% adults exposed heparin. Of those, about 29% 88% develop thrombosis. Most data on HIT-associated thrombosis children are confined anecdotal reports. Objective. To determine the incidence heparin-exposed children. Methods. We performed retrospective cohort study all patients admitted our pediatric intensive care unit between August 1996 and January 1999. Patients who received for...
Background. Cinacalcet rapidly normalizes serum calcium and reduces intact parathyroid hormone (PTH) levels in renal transplant patients with hypercalcaemia persistent hyperparathyroidism. The aim of this study is to evaluate the 6 months efficacy cinacalcet effect withdrawal on PTH such patients. Furthermore, impact bone turnover quality life was assessed. Methods. Twelve allograft recipients due hyperparathyroidism were treated for 26 weeks. then withdrawn check recurrence hypercalcaemia....