A5013487299- Iron Metabolism and Disorders
- Trace Elements in Health
- Hemoglobinopathies and Related Disorders
- Genetic factors in colorectal cancer
- Erythropoietin and Anemia Treatment
- Nuclear Structure and Function
- RNA Research and Splicing
- Biochemical effects in animals
- Blood transfusion and management
- Glycosylation and Glycoproteins Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Treatments and Studies
- Parathyroid Disorders and Treatments
- Diabetes Treatment and Management
- Innovations in Concrete and Construction Materials
- Additive Manufacturing and 3D Printing Technologies
- Chronic Kidney Disease and Diabetes
- Bone health and treatments
- BIM and Construction Integration
- Phytase and its Applications
- Folate and B Vitamins Research
Innsbruck Medical University
2021-2024
Universität Innsbruck
2020-2024
Christian Doppler Laboratory for Thermoelectricity
2023
Christian Doppler Klinik
2022
University Hospital Innsbruck
2022
Abstract Background Metabolic syndrome with its key components insulin resistance, central obesity, dyslipidaemia, and hypertension is associated a high risk for cardiovascular events all‐cause mortality in the general population. However, evidence that these findings apply to patients chronic kidney disease (CKD) moderately reduced estimated glomerular filtration rate and/or albuminuria limited. Objectives We aimed investigate association between metabolic outcomes CKD patients. Methods...
Abstract Background and Aims Haemochromatosis is characterized by progressive iron overload affecting the liver can cause cirrhosis hepatocellular carcinoma. Most haemochromatosis patients are homozygous for p.C282Y in HFE , but only a minority of individuals with this genotype will develop disease. The aim was to assess penetrance overload, fibrosis, carcinoma life expectancy. Methods A total 8839 from Austrian region Tyrol were genotyped variant between 1997 2021. Demographic, laboratory...
Zusammenfassung Die European Association for the Study of Liver (EASL) hat neue Clinical Practice Guidelines für Hämochromatose veröffentlicht. ist eine genetische Erkrankung, bei der ein Mangel des eisenregulierenden Hormons Hepcidin zu vermehrtem Eisenexport aus den Zellen und erhöhter intestinaler Eisenaufnahme führt. Dies führt Transferrinsättigung Bildung von toxischem nicht an Transferrin gebundenem Eisen, das Gewebe schädigen kann. Ein wesentliches Update in Leitlinien die...
Hämochromatose ist eine der häufigsten genetischen Erkrankungen in Europa, gekennzeichnet durch fortschreitende Eisenüberladung. Sie resultiert häufig aus Mutationen im HFE-Gen, besonders p.C282Y-Variante. Diese Krankheit kann zu schweren Organmanifestationen führen, wenn sie unbehandelt bleibt. Dieser Artikel bietet einen Überblick über Diagnose und Therapie Hämochromatose.
Background Anemia is present in up to two-thirds of patients undergoing colorectal surgery mainly caused by iron deficiency and inflammation. As anemia associated with increased risk perioperative death, diagnosis treatment preoperative according etiology have been recommended. Objective The aim the study was assess if association between survival determined severity alone or also etiology. Methods To determine prevalence etiology, hematological parameters, C-reactive protein, ferritin...
Objective Hemochromatosis is characterized by progressive iron overload and can cause cirrhosis hepatocellular carcinoma. The most common disease-associated genotype p.C282Y homozygosity in HFE. reported incidence of patients who are compound heterozygous for p.H63D as well homozygous individuals varies widely. We assessed the penetrance these genotypes.