Stefano Di Sandro

ORCID: 0000-0002-5217-8885
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About
Contact & Profiles
Research Areas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease and Transplantation
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease Diagnosis and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Organ Donation and Transplantation
  • Pancreatic and Hepatic Oncology Research
  • Hepatitis C virus research
  • Gallbladder and Bile Duct Disorders
  • Renal Transplantation Outcomes and Treatments
  • Pediatric Hepatobiliary Diseases and Treatments
  • Transplantation: Methods and Outcomes
  • HIV/AIDS drug development and treatment
  • Renal and Vascular Pathologies
  • Hepatitis B Virus Studies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Liver physiology and pathology
  • Gastric Cancer Management and Outcomes
  • Cancer, Lipids, and Metabolism
  • Renal cell carcinoma treatment
  • Viral-associated cancers and disorders
  • Abdominal Trauma and Injuries
  • Colorectal Cancer Treatments and Studies
  • Genetic and Kidney Cyst Diseases
  • Multiple and Secondary Primary Cancers

University of Modena and Reggio Emilia
2009-2025

Azienda Ospedaliero-Universitaria di Modena
2006-2024

GTx (United States)
2023

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2012-2021

Universidade Federal do Maranhão
2021

Novem (Netherlands)
2021

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2017-2020

Jackson and Tull (United States)
2020

University of Milano-Bicocca
2016-2020

University of Florence
2020

Objective: The aim of this study was to estimate probabilities achieving the statistical cure from hepatocellular carcinoma (HCC) with hepatic resection (HR) and liver transplantation (LT). Background: Statistical occurs when mortality a specific population returns values that general population. Resection are considered potentially curative therapies for HCC, but their effect on residual entire life-expectancy has never been investigated. Methods: Data 3286 HCC patients treated LT (n =...

10.1097/sla.0000000000002889 article EN Annals of Surgery 2018-08-03

The role of donation after cardiac death (DCD) in expanding the donor pool is mainly limited by incidence primary nonfunction (PNF) and ischemia-related complications. Even greater concern exists toward uncontrolled DCD, which represents largest potential DCD donors. We recently started first Italian series liver transplantation, using normothermic regional perfusion (NRP) 6 donors 1 controlled case to deal with legally required no-touch period 20 minutes. examined our 7 cases for PNF, early...

10.1002/lt.24666 article EN Liver Transplantation 2016-12-30

Donation after circulatory death (DCD) in Italy, given its 20-min stand-off period, provides a unique bench test for normothermic regional perfusion (NRP) and dual hypothermic oxygenated machine (D-HOPE).We coordinated multicenter retrospective Italian cohort study with 44 controlled DCD donors, who underwent NRP, to present transplant characteristics results. To rank our results according the high donor risk, we matched compared subgroup of 37 livers, preserved NRP D-HOPE, static-preserved...

10.1097/tp.0000000000003595 article EN Transplantation 2021-01-13

Donation after circulatory death (DCD) in Italy constitutes a relatively unique population because of the requirement no-touch period 20 minutes. The first aim this study was to compare liver transplantations from donors who were maintained on normothermic regional perfusion and suffered extended warm ischemia (DCD group, n = 20) with those extracorporeal membrane oxygenation (ECMO) succumbed brain (ECMO 17) standard (donation [DBD] 52). Second, we conducted an explorative analysis DCD group...

10.1002/lt.25312 article EN Liver Transplantation 2018-07-19

Major concerns about donor morbidity and mortality still limit the use of living liver transplantation (LDLT) to overcome organ shortage. The present study assessed safety in LDLT Italy reporting postoperative outcomes 246 donation procedures performed by 7 transplant centers. Outcomes were evaluated over 2 time periods using validated Clavien 5‐tier grading system, several clinical variables analyzed determine risk factors for morbidity. Different grafts obtained from (220 right lobe, 10...

10.1002/lt.24651 article EN Liver Transplantation 2016-10-13

To report the first European series of full robotic whole liver transplantation (RLT) with technical details and future perspectives.

10.1097/sla.0000000000006420 article EN Annals of Surgery 2024-07-02

Some experimental trials have demonstrated that rapamycin (RAPA) is able to inhibit HIV-1 progression in three different ways: (1) reducing CCR5-gene transcription, (2) blocking interleukin-2 intracellular secondary messenger (mammalian target of rapamycin), and (3) up-regulating the beta-chemokine macrophage inflammatory protein (MIP; MIP-1alpha MIP-1beta). We present preliminary results a prospective nonrandomized trial concerning first HIV patient series receiving RAPA monotherapy after...

10.1097/tp.0b013e3181c7dcc0 article EN Transplantation 2010-03-15

The aim of this study was to collect data from patients who underwent liver transplantation (LT) for adenomatosis; analyze the symptoms, characteristics disease, and recipient outcomes; better define role LT in rare indication. This retrospective multicenter study, based on European Liver Transplant Registry, encompassed adenomatosis between January 1, 1986, July 15, 2013, Europe. Patients with glycogen storage disease (GSD) type IA were not excluded. included 49 patients. Sixteen had GSD, 7...

10.1002/lt.24417 article EN Liver Transplantation 2016-02-26

Early-stage hepatocellular carcinoma could benefit from upfront liver resection (LR) or transplantation (LT), but the optimal strategy in terms of tumor-related outcomes is still debated. We compared oncological LR and LT for carcinoma, stratifying study population into a low-, intermediate-, high-risk class according to risk death at 5-y predicted by previously developed prognostic model. The impact tumor pathology on low- intermediate-risk patients undergoing was investigated as secondary...

10.1097/tp.0000000000004593 article EN Transplantation 2023-04-06

ABSTRACT Introduction Liver transplantation (LT) is the sole curative option for liver failure and other primary conditions. However, limited number of suitable donors compared with growing patients requiring LT remains a leading cause mortality among those on waiting list. This has resulted in expansion criteria donor eligibility. The sequential combination ex situ reperfusion, dHOPE, NMP helps reduce occurrence ischemia–reperfusion injury assess organ viability prior to transplantation....

10.1111/aor.14936 article EN Artificial Organs 2025-02-19
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