A5082182487- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Surgical Simulation and Training
- Cardiac, Anesthesia and Surgical Outcomes
- Diverticular Disease and Complications
- Frailty in Older Adults
- Anorectal Disease Treatments and Outcomes
- Pancreatic and Hepatic Oncology Research
- Nutrition and Health in Aging
- Neuroblastoma Research and Treatments
- Adrenal and Paraganglionic Tumors
- Bariatric Surgery and Outcomes
- Cancer, Hypoxia, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Gastrointestinal disorders and treatments
- Metastasis and carcinoma case studies
- Neuroendocrine Tumor Research Advances
- Gastrointestinal Tumor Research and Treatment
- Parathyroid Disorders and Treatments
- Appendicitis Diagnosis and Management
- Body Contouring and Surgery
- Enhanced Recovery After Surgery
- Pelvic floor disorders treatments
Mayo Clinic
2020-2024
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2019-2024
WinnMed
2020-2024
Ospedale Maggiore
2019-2023
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2017-2021
Research Network (United States)
2021
Aims Community College
2021
University of Milan
2017-2020
Medtronic (Italy)
2019
Alessandro Manzoni Hospital
2017
Abstract Background Accurate quality of life (QoL) data and functional results after cancer surgery are lacking for older patients. The international, multicenter Geriatric Oncology Surgical Assessment Functional rEcovery Surgery (GOSAFE) Study compares QoL before identifies predictors decline in QoL. Methods GOSAFE prospectively collected major elective on adults (≥70 years). Frailty assessment was performed postoperative outcomes recorded (30, 90, 180 days postoperatively) together with by...
The GOSAFE study evaluates risk factors for failing to achieve good quality of life (QoL) and functional recovery (FR) in older patients undergoing surgery colon rectal cancer.
To verify the prognostic value of pathologic and radiological tumor response after neoadjuvant chemotherapy in treatment locally advanced gastric adenocarcinoma.
Abstract Background The aim of this study was to review risk factors for conversion in a cohort patients with rectal cancer undergoing minimally invasive abdominal surgery. Methods A retrospective analysis performed consecutive operated on from February 2005 April 2018. Adult low anterior resection or abdominoperineal primary adenocarcinoma by approach were included. Exclusion criteria lack research authorization, stage IV recurrent cancer, and emergency Risk investigated using logistic...
Abstract Background and Objective Perioperative chemotherapy (PC) with radical surgery represents the gold standard of treatment for resectable advanced gastric cancer (GC). The prognostic value pathological tumor regression grade (TRG) induced by neoadjuvant (NACT) is not clearly established. This study aimed to investigate correlation between TRG survival in GC. Methods Patients affected GC undergoing PC were considered. was assessed each patient according Becker's grading system....
Abstract Magnetic resonance imaging (MRI) is routinely used for preoperative tumor staging and to assess response therapy in rectal cancer patients. The aim of our study was evaluate the accuracy MRI based restaging after neoadjuvant chemoradiotherapy (CRT) predicting pathologic response. This multicenter cohort included adult patients with histologically confirmed locally advanced adenocarcinoma treated CRT followed by curative intent elective surgery between January 2014 December 2019 at...
Patterns of white blood cells differential count with low lymphocyte number have been associated poor outcome following sepsis, burns and trauma. Lymphocytopenia, measured preoperatively or in response to surgical stress, may affect complications after bowel resection.Clinical characteristics values, both pre- post-operatively a cohort patients submitted intestinal resection anastomosis from June 2014 2017 our General Surgery Division, were retrospectively analyzed. Multivariate logistic...
Abstract Utility of adjuvant chemotherapy for stage II cancer remains a matter debate. Clinical guidelines suggest tumors with high‐risk features, in particular T4 tumors. However, limited consensus exists regarding the importance other features (lymphovascular or perineural invasion, microsatellite instability). Our study aimed to investigate impact IIA (T3N0) colon patients. Patients who underwent colectomy adenocarcinoma (2010‐2015) were identified National Cancer Database (NCDB) and...
<ns4:p><ns4:bold>Background</ns4:bold>: HD systems are routinely used in laparoscopic surgery, 4K ultra monitors mainly available within specialized, high-volume centers. The higher resolution of video could upgrade the surgical performance improving intraoperative and post-operative outcomes.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: We performed a retrospective comparative analysis parameters outcomes cohort patients operated on for elective procedures colo-rectal cancer during two...
Abstract Aim Locally advanced rectal cancer (LARC) is commonly treated with neoadjuvant chemoradiotherapy (nCRT) and total mesorectal excision (TME) to reduce local recurrence (LR) improve survival. However, LR, particularly associated lateral lymph node (LLN) involvement, remains a concern. The aim of this study was investigate preoperative factors LLN involvement their impact on LR rates in LARC patients undergoing nCRT curative surgery. Method This multicentre retrospective study,...
Hospital readmission rate is an important quality metric and has been recognized as a key measure of hospital value-based purchasing programs.This study aimed to assess the risk factors for with focus on potentially preventable early readmissions within 48 hours discharge.This retrospective cohort study.This was conducted at tertiary academic facility standardized enhanced recovery pathway.Consecutive patients undergoing elective major colorectal resections between 2011 2016 were...
The burden of disease caused by Streptococcus agalactiae has increased significantly among older adults in the last decades. Group B streptococcus infection can be associated with invasive and severe clinical syndromes, such as meningitis endocarditis. We present case a 56-year-old man who developed multiple mycotic aneurysms right hepatic artery massive splenic infarction rare complications infective patient underwent urgent ligation splenectomy. postoperative course was complicated an...
BACKGROUND: Surgical treatment for transverse colon cancer involves either extended colectomy or segmental resection, depending on the location of tumor and surgeon perspective. However, oncological safety resection has not yet been established in large cohort studies. OBJECTIVE: This study aims to compare versus terms outcomes. DESIGN: was a retrospective study. SETTINGS: conducted using nationwide cohort. PATIENTS: A total 66,062 patients who underwent with curative intent stage I III...
Chylothorax is a severe condition resulting from the accumulation of chyle into pleural space. We report treatment postoperative chylothorax after resection mediastinal ganglioneuroma in 17-year-old boy. Since conservative measures were not effective, we performed direct ligation lymphatic vessels and pleurodesis. At subsequent surgical re-exploration for persisting chylothorax, accurate inspection cavity revealed residual leakage. Fibrin sealant patches (TachoSil®) placed over source leak...
Background: Despite its potential oncologic benefit, complete mesocolic excision (CME) has rarely been offered to elderly patients. The present study evaluated the effect of age on postoperative outcomes among patients undergoing laparoscopic right colectomies with CME for right-sided colon cancer (RCC). Methods: Data RCC between 2015 and 2018 were retrospectively analyzed. Selected divided into two groups: under-80 group over-80 group. Surgical, pathological, oncological groups compared....
Introduction: Symptomatic uncomplicated diverticular disease (SUDD) is characterized by abdominal pain and altered bowel function may affect quality of life. When symptoms are severe conservative therapy ineffective, surgical intervention becomes an option. Objective: This study aims to investigate life after elective sigmoidectomy for patients affected SUDD. Materials Methods: Retrospective multicenter review consecutive SUDD that underwent laparoscopic from January 2015 March 2018. was...