Maria Vittoria Davì
A5045972592- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Cancer Genomics and Diagnostics
- Neuroblastoma Research and Treatments
- Pancreatic and Hepatic Oncology Research
- Pituitary Gland Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Adrenal and Paraganglionic Tumors
- Evolution and Genetic Dynamics
- Genomics and Chromatin Dynamics
- Bioinformatics and Genomic Networks
- Genomics and Phylogenetic Studies
- Obstructive Sleep Apnea Research
- Growth Hormone and Insulin-like Growth Factors
- RNA modifications and cancer
- Chromosomal and Genetic Variations
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Nutrition, Genetics, and Disease
- Genetic Syndromes and Imprinting
- Genomics and Rare Diseases
- Cancer, Hypoxia, and Metabolism
- Genetic factors in colorectal cancer
- Thyroid Cancer Diagnosis and Treatment
- Diabetes Treatment and Management
University of Verona
2012-2024
Azienda Ospedaliera Universitaria Integrata Verona
2014-2022
Institució Catalana de Recerca i Estudis Avançats
2020
Heidelberg University
2020
Policlinico S.Orsola-Malpighi
2018
University of Insubria
2014
Whether sleep apnoea syndrome (SAS) subsides after biochemical and clinical remission of acromegaly is controversial.To assess the presence SAS in a cohort acromegalic patients, which included subgroup with active disease remission, to evaluate independent predictors SAS.Cross-sectional longitudinal study.Italian university department internal medicine.About 36 patients: 18 controlled.Polysomnography was performed all patients repeated six achieving control. Echocardiographic parameters were...
<h3>Importance</h3> Data about the optimal timing for initiation of peptide receptor radionuclide therapy (PRRT) advanced, well-differentiated enteropancreatic neuroendocrine tumors are lacking. <h3>Objective</h3> To evaluate association upfront PRRT vs chemotherapy or targeted with progression-free survival (PFS) among patients advanced who experienced disease progression after treatment somatostatin analogues (SSAs). <h3>Design, Setting, and Participants</h3> This retrospective,...
Evidence is limited regarding outcome of patients with ectopic Cushing's syndrome (ECS) due to neuroendocrine tumors (NETs).We assessed the prognostic factors affecting survival NETs and ECS.Retrospective analysis clinicopathological features, severity hormonal syndrome, treatments from a large cohort ECS collected 17 Italian centers.Our series included 110 patients, 58.2% female, mean (±s.d.) age at diagnosis 49.5 ± 15.9 years. The main sources ACTH were bronchial carcinoids (BC) (40.9%),...
Objective: The objective of the present analysis is 2-fold: first, to define evolution time trends on surgical approach pancreatic neuroendocrine neoplasms (Pan-NENs); second, perform a complete predictors oncologic outcome. Background: Reflecting their rarity and heterogeneity, Pan-NENs represent clinical dilemma. In particular, there scarcity data regarding long-term follow-up after resection. Methods: From Institutional Pan-NEN database, 587 resected cases from 1990 2015 were extracted....
Background: The optimal treatment sequencing for advanced, well-differentiated pancreatic neuroendocrine tumors (pNETs) is unknown. We performed a multicenter, retrospective study to evaluate the best sequence in terms of progression-free survival first-line (PFS1) and second-line (PFS2), overall among patients with pNETs. Methods: This multicenter retrospectively analyzed prospectively collected data sporadic pNETs who received at least two consecutive therapeutic lines, evidence...
Management of malignant insulinomas is challenging due to the need control both hypoglycaemic syndrome and tumor growth. Literature data limited small series.To analyze clinico-pathological characteristics, treatments prognosis patients with insulinoma.Multicenter retrospective study on 31 (male: 61.3%) diagnosed between 1988 2017.The mean age at diagnosis was 48 years. The NET diameter 41 ± mm, 70.8% NETs were G2. Metastases widespread in 38.7%, hepatic 41.9% only lymph nodal 19.4%. In...
Background Germline mutations in the aryl hydrocarbon receptor-interacting protein ( AIP ) gene and p27 KIP1 encoding CDKN1B have been associated with two well-defined hereditary conditions, familial isolated pituitary adenoma (FIPA) multiple endocrine neoplasia type 4 (MEN4). Somatotropinomas are present most mutated FIPA kindreds, as well two-thirds of MEN4 patients who carry tumors. Methods DNA samples 131 Italian sporadic acromegalic including 38 individuals tumors, six families (four...
<i>Aim:</i> To assess presentation and outcome of pancreaticoduodenal endocrine tumors (PDETs) in a single center series multiple neoplasia type 1 (MEN1) patients. <i>Methods:</i> Retrospective analysis prospectively collected data MEN1 patients observed at the University Verona. <i>Results:</i> Thirty-one had PDETs, including 16 nonfunctioning (NF), 6 insulinomas 9 Zollinger-Ellison syndrome (ZES). In these (52%), PDET was manifestation which led to...
Objectives 68Ga-DOTATOC (Ga) positron emission tomography (PET)/computed (CT) is recommended in the workup of pancreas neuroendocrine tumors (PanNETs); evidence suggests that 18F-FDG (F) PET/CT can also provide prognostic information. Aims this study were to assess role combined Ga- and F-PET/CT evaluation grade (G) 1–2 PanNETs test correlation between positivity tumor grade. Methods Preoperative 35 patients with surgically resected G1-2 evaluated. For grading, 2010 World Health Organization...
Background: Thyroid remnant ablation of differentiated thyroid carcinoma (DTC) patients is traditionally performed after levothyroxine withdrawal. Recombinant human TSH (rhTSH) administration increases serum levels without inducing hypothyroidism.
Runx2, a master gene of osteogenic differentiation, is also expressed in nonosseous cancer cells. Microcalcifications are characteristic papillary thyroid carcinoma and represent useful find for diagnosis. However, the molecular expression differentiation transcription factor Runx2 has been poorly investigated this tumor.The aim study was to investigate mRNA normal pathological tissue, serum, circulating non-hematopoietic cells.The performed Endocrine Unit Internal Medicine "Azienda...
Abstract Background The incidence of neuroendocrine neoplasm (NEN) and related carcinoid syndrome (CaS) has increased markedly in recent decades, women appear to be more at risk than men. As per other tumors, gender may relevant influencing the clinical prognostic characteristics NEN-associated CS. However, specific data on are still lacking. Purpose To evaluate differences presentation outcome CaS. Methods Retrospective analysis 144 CaS patients from 20 Italian high-volume centers was...