A5031024449- Pituitary Gland Disorders and Treatments
- Neuroendocrine Tumor Research Advances
- Adrenal Hormones and Disorders
- Adrenal and Paraganglionic Tumors
- Cerebrospinal fluid and hydrocephalus
- Pancreatic and Hepatic Oncology Research
- Hormonal Regulation and Hypertension
- Growth Hormone and Insulin-like Growth Factors
- Pancreatic function and diabetes
- Thyroid Disorders and Treatments
- Neonatal Health and Biochemistry
- Sarcoidosis and Beryllium Toxicity Research
- Particle accelerators and beam dynamics
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Diabetes Treatment and Management
- Head and Neck Surgical Oncology
- Glioma Diagnosis and Treatment
- Lung Cancer Research Studies
- Peroxisome Proliferator-Activated Receptors
- Infectious Diseases and Tuberculosis
- Pharmacological Effects and Toxicity Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Bone health and treatments
Cliniques Universitaires Saint-Luc
2016-2025
UCLouvain
2020-2023
Centre Hospitalier de Mouscron
2013-2015
Abstract Context Current guidelines for distinguishing Cushing's disease (CD) from ectopic ACTH secretion (EAS) are questionable, as they use pituitary magnetic resonance imaging (MRI) first-line investigation all patients. CRH testing is no longer available, and suggest performing inferior petrosal sinus sampling (BIPPS), an invasive rarely available investigation, in many Objective To establish noninvasive personalized diagnostic strategies based on the probability of EAS estimated simple...
Abstract Objective Primary aldosteronism (PA) is one of the most frequent causes secondary hypertension. Although clinical practice guidelines recommend a diagnostic process, details steps remain incompletely standardized. Design In present SCOT-PA survey, we have investigated diversity approaches utilized for each step in different expert centers through survey using Google questionnaires. A total 33 from 3 continents participated. Results We demonstrated prominent conditions blood...
Journal Article Accepted manuscript Response to Letter the Editor from Lamas: Personalized Noninvasive Diagnostic Algorithms Based on Urinary Free Cortisol in ACTH-dependant Cushing's Syndrome" Get access Antoine Tabarin, Tabarin Department of Endocrinology, diabetes and nutrition, University Hospital Bordeaux, 33604 Pessac, France Corresponding author: Pr France. [email protected] https://orcid.org/0000-0003-1231-3306 Search for other works by this author on: Oxford Academic Google Scholar...
Abstract Introduction Equivocal or negative pituitary magnetic resonance imaging (MRI) findings raise a significant challenge in the management of persistent recurrent Cushing’s disease (CD), compromising chances success further transsphenoidal surgery (TSS). The aim our study was to determine diagnostic utility 11C-methionine (MET) positron emission tomography coupled with computerized (PET/CT) localizing residual relapsing corticotroph adenoma. Methods We retrospectively analyzed results...
Introduction Intravenous etomidate infusion is effective to rapidly lower cortisol levels in severe Cushing’s syndrome (CS) the intensive care unit (ICU). Recently, treatment has also been proposed at doses non-ICU wards, but it not yet clear how this approach compares ICU treatment. Methods We compared data from patients with CS treated high starting of (median: 0.30 mg/kg BW/day) or 0.025 medical wards. Results Fourteen were included, among which ten low (LD) and four (HD). All had...
Current guidelines recommend different postpartum approaches for patients started on levothyroxine (LT4) during pregnancy.
Isolated maternal hypothyroxinaemia (IH) is defined as low FT4 (<5th percentile) and normal thyroid-stimulating hormone. There concern on its potential negative effects the mother offspring.We aimed to evaluate prevalence of IH assess consequences foetal outcomes.From a total 1300 consecutive pregnant women recruited during prenatal screen (mean gestational age, 11·8 weeks), thyroid function parameters were assessed in 879 women. After exclusion with T4 supplements, twin pregnancies...
In recent years, endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) has emerged as an alternative nonsurgical treatment for pancreatic neuroendocrine tumours. The aim of our study was to assess the long-term follow-up patients treated with EUS-RFA a sporadic insulinoma in centre terms efficacy, safety and risk recurrence.
Clinical practice guidelines recommend the Lateralization Index (LI) as standard for determining surgical eligibility in primary aldosteronism (PA). Our goal was to identify optimal LI cut-offs adrenal venous sampling (AVS) diagnosing PA that is amenable cure.
Summary A 26-year-old woman presented with severe postpartum headaches. Magnetic resonance imaging (MRI) revealed a symmetric, heterogeneous enlargement of the pituitary gland. Three months later, she developed central diabetes insipidus. diagnosis hypophysitis was suspected and corticosteroids were prescribed. Six mass showed further characteristics necrotic abscess peripheral shell infiltration hypothalamus. Transsphenoidal surgery performed, disclosing pus-filled cavity which drained. No...
Surgery of pheochromocytomas (PCs) still carries a high risk haemodynamic complications during the perioperative period. We aimed to evaluate influence their secretory phenotype and preoperative alpha-blocker treatment on surgical outcome.A retrospective monocentric study at tertiary medical centre.In this study, 80 consecutive patients operated by same team for PC between 1988 2018.Diagnosis was based typical symptoms signs in 58 patients, genetic testing 12 work-up an adrenal incidentaloma...
Abstract Background Ectopic ACTH pituitary adenomas (EAPA), located outside the sella turcica and deriving from cellular remnants of Rathke’s pouch are a very rare cause Cushing’s syndrome (CS). The diagnosis is often difficult delayed, even after comprehensive work-up. To our knowledge, we report for first time an ectopic corticotroph tumor posterior wall sphenoid sinus, leading to false positive results bilateral inferior petrosal sinus sampling (BIPPS) which was finally localized by...
A 52-year-old female presented with recurrent episodes of fasting or post-absorptive hypoglycemia. 72-h test confirmed endogenous hyperinsulinemia. Conventional imaging was unremarkable. Selective pancreatic arterial calcium stimulation and hepatic venous sampling showed a maximum calcium-stimulated insulin concentration from several areas, mainly the proximal splenic artery gastroduodenal artery, suggesting presence one more occult insulinoma(s) in region body. 68Ga-DOTA-exendin-4 PET/CT...
Amyloid infiltration of endocrine glands has been reported, mostly in the thyroid, pancreas, adrenals, and testes, but affected patients do not frequently exhibit overt insufficiency. Here we report case a patient with complete anterior hypopituitarism probably due to known systemic amyloidosis.Our male Caucasian was diagnosed Crohn's disease at age 22 years. At 37, he developed secondary renal amyloidosis, which resulted end-stage failure. He received living-donor kidney transplant 57,...
Abstract Disclosure: R. Furnica: None. F. Devuyst: C. Mathey: S. Constantinescu: De Herdt: L. Renaud: D.M. Maiter: Introduction: Equivocal or negative pituitary magnetic resonance imaging (MRI) findings pose a significant challenge in the management of persistent recurrent Cushing’s disease (CD), compromising chances success further transsphenoidal surgery (TSS). The aim our study was to determine diagnostic utility [1][1]C-methionine (MET) positron emission tomography coupled with...
Abstract Disclosure: R. Furnica: None. F. Devuyst: C. Mathey: S. Constantinescu: De Herdt: L. Renaud: D.M. Maiter: Introduction: Equivocal or negative pituitary magnetic resonance imaging (MRI) findings pose a significant challenge in the management of persistent recurrent Cushing’s disease (CD), compromising chances success further transsphenoidal surgery (TSS). The aim our study was to determine diagnostic utility [1][1]C-methionine (MET) positron emission tomography coupled with...
Aims We aimed to compare EUS-guided radiofrequency ablation (EUS-RFA) and surgical resection for the treatment of sporadic, non-metastatic pancreatic insulinoma (PI).
Complicated Rathke's cleft cyst (RCC) is a rare occurrence of symptomatic bleeding or growth previously asymptomatic (and often undiagnosed) intrasellar derived from remnants pouch, situated on the midline between adeno- and neurohypophysis. Symptoms may be identical to those pituitary apoplexy: acute onset headache, hypopituitarism, neurological disturbances. Both syndromes also exhibit similar appearance large haemorrhagic sellar mass at initial radiological evaluation. We report two...
Summary A 26-year-old woman presented with persistent headache and tiredness. Biological investigations disclosed a moderate inflammatory syndrome, low PTH-hypercalcemia complete anterior hypopituitarism. magnetic resonance imaging (MRI) of the pituitary gland was performed revealed symmetric enlargement heterogeneous signal. Ophthalmological examination showed an asymptomatic bilateral posterior uveitis, diagnosis sarcoidosis suspected. As localization lymphadenopathies on fused whole-body...