A5074129899- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Endometriosis Research and Treatment
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Genetic factors in colorectal cancer
- Cancer-related molecular mechanisms research
- Neuroblastoma Research and Treatments
- Reproductive System and Pregnancy
- Cancer Immunotherapy and Biomarkers
- Intraperitoneal and Appendiceal Malignancies
- Sarcoma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Cancer Cells and Metastasis
- Breast Lesions and Carcinomas
- Estrogen and related hormone effects
- Glioma Diagnosis and Treatment
- Lung Cancer Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Ovarian function and disorders
- HER2/EGFR in Cancer Research
- Immunotherapy and Immune Responses
- Colorectal Cancer Screening and Detection
Agostino Gemelli University Polyclinic
2021-2025
Università Cattolica del Sacro Cuore
2021-2025
Istituto Dermopatico dell'Immacolata
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2024
University of Genoa
2020-2023
University of Naples Federico II
2021
University of the Sacred Heart
2021
University of Bologna
2021
Ospedale Policlinico San Martino
2020
Azienda di Rilievo Nazionale ed Alta Specializzazione
2011
Abstract The existing Intraductal Papillary Mucinous Neoplasm (IPMN) risk stratification relies on clinical and histological factors, resulting in inaccuracies leading to suboptimal treatment. This is due the lack of appropriate molecular markers that can guide patients toward best therapeutic options. Here, we assess confirm subtype-specific for IPMN across two independent cohorts using Spatial Transcriptomics (ST) technologies. Specifically, identify HOXB3 ZNF117 as Low-Grade Dysplasia,...
Abstract Background Isolated parenchymal splenic relapse is a rare condition experienced by patients presenting with recurrent ovarian cancer (ROC). 1–3 In such cases, complete secondary cytoreductive surgery (SCS) followed chemotherapy offers significant overall survival benefits for platinum-sensitive ROC patients. Randomized trials as DESKTOP-3 and SOC-1 described splenectomy during SCS in 6–15% of 4,5 Robotic-assisted (RAS) advanced three-dimensional (3D) imaging reconstruction can be...
Gynecological neuroendocrine neoplasms (NENs) are extremely rare, accounting for 1.2-2.4% of the NENs. The aim this study was to test cervical NENs novel markers potential utility differential diagnosis and target therapy.All cases our center (n = 16) were retrieved tested by immunohistochemistry (IHC) 12 including differentiation (chromogranin A, synaptophysin, CD56), transcription factors (CDX2 TTF1), proteins p40, p63, p16INK4a, p53, somatostatin receptors subtypes (SST2-SST5)...
Background: Spontaneous regression of tumors is a rare phenomenon in which cancer volume reduced or, alternatively, tumor completely disappears the absence any pharmacological treatment. This has previously been described several tumors, such as neuroblastomas, testicular malignancies, renal cell carcinomas, melanomas, and lymphomas. remission also documented breast cancer; however, it represents an extremely poorly understood phenomenon, with only few reported cases literature. Methods: We...
Abstract Colorectal cancer (CRC) is a devastating disease, ranking as the second leading cause of cancer-related deaths worldwide. Immune checkpoint inhibitors (ICIs) have emerged promising treatments; however, their efficacy largely restricted to subgroup microsatellite instable (MSI) CRCs. In contrast, stable (MSS) CRCs, which account for majority cases, exhibit variable and generally weaker response ICIs, with only subset demonstrating exceptional responsiveness. Identifying novel...