- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Cervical Cancer and HPV Research
- Parasitic infections in humans and animals
- Congenital Anomalies and Fetal Surgery
- Cancer Risks and Factors
- Cancer Diagnosis and Treatment
- Amoebic Infections and Treatments
- Ultrasound and Hyperthermia Applications
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Reproductive Biology and Fertility
- Cancer-related molecular mechanisms research
- Multiple and Secondary Primary Cancers
- Ureteral procedures and complications
- Reproductive System and Pregnancy
- Gestational Trophoblastic Disease Studies
- Colorectal Cancer Surgical Treatments
- Minimally Invasive Surgical Techniques
- RNA Research and Splicing
- Neuroendocrine Tumor Research Advances
- Ultrasound Imaging and Elastography
- COVID-19 and healthcare impacts
- Genetic factors in colorectal cancer
- Neuroblastoma Research and Treatments
Agostino Gemelli University Polyclinic
2019-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2024-2025
Università Cattolica del Sacro Cuore
2022-2023
Recent guidelines recommend the sentinel lymph node (SLN) technique in uterine cancers, as it is associated with lower perioperative complications.1 Image-guided surgery can address some limitations of SLN procedures, such low frozen-section accuracy and risk empty packets,2-4 by providing real-time assessment.5,6 This video describes surgical procedure intraoperative robotic ultrasound examination for assessment. The Arietta L43K (2-12 MHz, Hitachi, Japan) drop-in probe was used to assist...
Lynch Syndrome (LS) represents the hereditary condition that is most frequently associated with endometrial cancer (EC). The aim of this study to assess presence in young women mismatch repair (MMR)-deficient atypical hyperplasia (AEH) and non-myoinvasive FIGO G1 endometrioid EC its possible impact on outcome conservative treatment.Six MMR-deficient cases identified from a previous cohort 69 conservatively treated patients were selected be screened for germline mutations MMR genes. In each...
Sentinel lymph node (SLN) biopsy is part of surgical treatment apparent early-stage cervical cancer. SLN routinely analyzed by ultrastaging and immunohistochemistry. The aim this study was to assess the survival patients undergoing one-step nucleic acid amplification (OSNA) compared with ultrastaging.
Abstract Purpose To assess the rate of bilateral sentinel lymph node (SLN) detection with indocyanine green (ICG), to evaluate sensitivity and negative predictive value cervical cancer patients undergoing open radical hysterectomy; compare versus minimally invasive SLN biopsy performance factors related no/unilateral mapping. Methods We retrospectively reviewed consecutive FIGO 2018 stage IA1 lymph-vascular space involvement IIB IIIC1p carcinoma who underwent mapping ICG followed by...
Occult parametrial involvement in apparent early-stage cervical cancer might be overlooked with standard pathologic assessment. The primary endpoint of the present study was to assess rate positive lymph nodes and microscopic continuous or discontinuous involvement. This is a retrospective, single-center, observational including patients FIGO 2018 stage IA1-IIA1 IIIC1p whom bilateral sentinel node (SLN) detection ultrastaging SLN were performed according institutional protocol, surgery as...
Abstract Background Exclusive chemoradiation (E-CT/RT) represents the standard of treatment for locally advanced cervical cancer (LACC). Chemoradiation (CT/RT) followed by radical surgery (RS) may play a role patients with suboptimal response to CT/RT or in low-income countries limited access radiotherapy. Histologic assessment residual tumor after and RS allows accurate definition prognostic categories. Methods Data on FIGO stages 1B2 4A managed from June 1996 March 2020 were...
<h3>Introduction/Background</h3> Cervical cancer is the fourth most common in women worldwide and almost 50% of cases are diagnosed younger than 35 years old. According to international guidelines, fertility sparing treatment young patients evaluated early-stage disease with tumors <4 cm, negative nodes non-aggressive histological subtype. Glassy cell cervical carcinoma (GCCC) an extremely rare poorly differentiated carcinoma, characterized by aggressive behavior poor prognosis no...
Peritoneal involvement may be overlooked in patients with locally advanced cervical cancer (LACC). This lead to underestimation of prognosis and undertreatment limited locoregional disease locations. However, staging laparoscopy LACC is not routinely performed. The primary aim this study was determine the proportion peritoneal metastasis by factors associated LACC. Secondary aims were evaluate performance imaging detecting metastasis.
The primary aim of the present study was to investigate prognostic impact (defined as disease-free-DFS and overall survival-OS) ultrasound scan tumor parameters, patients' anthropometric their combination in early-stage cervical cancer. secondary assess relation between characteristics pathological parametrial infiltration. This is a retrospective, single-center, observational cohort study. Consecutive patients with clinical FIGO 2018 stage IA1-IB2 IIA1 cancer who underwent preoperative...
<h3>Introduction/Background</h3> Sentinel lymph node (SLN) biopsy is part of surgical treatment apparent early-stage cervical cancer. SLN routinely analyzed by ultrastaging and immunohistochemistry. Recently, one-step nucleic acid amplification (OSNA) method has been demonstrated to be an accurate tool detect metastases in cancer with the advantage a rapid standardized technique no sampling bias. Nevertheless, oncological safety OSNA not previously explored. The aim this study was assess...
Echinococcosis is an endemic disease caused by Echinococcus granulosus. The hydatid cysts are usually located in the liver (65-70%) and lungs (25%), whereas breast, adrenal, appendix, omentum, retroperitoneal unusual sites for formation. We describe a case of 61-year-old woman reporting pelvic pain, weight loss, anemia. had history left nephrectomy due to kidney cancer, deep venous thrombosis treated with bilateral arterial iliac stenting. At transvaginal ultrasound examination, right...
<h3>Introduction/Background</h3> The benefit of surgical staging with laparoscopy remains controversial and the prognostic significance peritoneal involvement in locally advanced cervical cancer (LACC) patients has still to be demonstrated. Peritoneal upstages FIGO stage IVB, which can from addition bevacizumab standard chemotherapy, after FDA approval. aim this study is determine rate a large series LACC. <h3>Methodology</h3> Retrospective cohort approved by Institutional Review Board....