A5030641304- Anesthesia and Pain Management
- Endometriosis Research and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Hernia repair and management
- Pediatric Pain Management Techniques
- Nerve Injury and Rehabilitation
- Anesthesia and Sedative Agents
- Intraperitoneal and Appendiceal Malignancies
- Uterine Myomas and Treatments
- Pregnancy-related medical research
- Venous Thromboembolism Diagnosis and Management
- Pain Mechanisms and Treatments
- Peripheral Nerve Disorders
- Education, Healthcare and Sociology Research
- Enhanced Recovery After Surgery
- Hospital Admissions and Outcomes
- Healthcare Operations and Scheduling Optimization
- Radiation Dose and Imaging
- Acupuncture Treatment Research Studies
- IL-33, ST2, and ILC Pathways
- Thermoregulation and physiological responses
- Inflammatory Bowel Disease
- Myofascial pain diagnosis and treatment
Aarhus University Hospital
2008-2024
Aarhus University
2012-2024
Copenhagen University Hospital
2016
St George's Hospital
2016
Innsbruck Medical University
2016
Universität Innsbruck
2016
Toronto Western Hospital
2016
University of Toronto
2016
Danish Pain Research Center
2006-2013
Danish National Research Foundation
2004
Chronic post-operative pain is a well-recognized problem after various types of surgery, but little known about chronic orthopedic surgery. Severe pre-operative the primary indication for total hip arthroplasty (THA). Therefore, we examined prevalence THA in relation to and early pain.A questionnaire was sent 1231 consecutive patients who had undergone 12-18 months previously, whose operations been reported Danish Hip Arthroplasty Registry.The response rate 93.6%. Two hundred ninety-four...
Women scheduled to undergo hysterectomy for benign indications frequently have preoperative pelvic pain, but it is largely unknown why pain in some cases persists or even develops after surgery. This nationwide questionnaire and database study describes identifies risk factors chronic postsurgical 1 yr indications.A was mailed 1,299 women hysterectomy. The response rate 90.3%, the presence of persistent correlated indication surgery, surgical procedure, type anesthesia, other perioperative...
Despite standard medical treatment endometriosis is often associated with disabling pain and poor quality of life (QoL). Studies indicate that psychological interventions (PIs) may improve QoL, yet studies on the effects PIs for women are sparse limited by low-quality study designs. Therefore, this aimed, in a rigorous three-armed design, to evaluate effect chronic pelvic (CPP) QoL endometriosis.
Inguinal herniotomy is one of the most frequent surgical procedures and chronic pain affecting everyday activities reported in approximately 10% patients. However, neurophysiological changes underlying pathophysiological mechanisms postherniotomy are not known detail, thereby precluding advances treatment strategies prophylaxis. Therefore, we examined forty-six patients reporting moderate to severe daily for more than a year postoperatively, compared them with control group without 1 yr...
Chronic pain after hysterectomy is reported by 5% to 32% of women, but it unknown whether the a result surgery or can be attributable other factors such as preoperative and postoperative pain, physical, psychosocial status. The aim this prospective study was therefore role possible predictors for 4 months hysterectomy.Ninety women referred benign conditions completed study. were interviewed questionnaires before 3 weeks months. Questions about location, intensity, frequency, well medical...
<h3>Background and Objectives</h3> Ultrasound-guided techniques for pudendal nerve block have been described at the level of ischial spine transperineally. Theoretically, however, blockade inside Alcock canal with a small local anesthetic volume would minimize risk sacral plexus anesthetize all 3 branches before they ramify in ischioanal fossa. This technical report describes new ultrasound-guided technique to nerve. The indicates an easy effective roadmap target by following margin hip bone...
Previous studies on sensory function in persistent postherniotomy pain (PPP) have only identified pressure threshold to be significantly different from pain-free patients despite several reporting cutaneous and wind-up phenomena. However the limited number of studied hinders evaluation potential subgroups for further investigation and/or treatment allocation. Thus we used a standardized QST protocol evaluate functions PPP control patients, allow individual characterization calculated...
Persistent postsurgical pain is a well-recognized problem after various types of surgery such as amputation and thoracotomy. The prevalence persistent pain, the extent to which it involves neuropathic highly dependent on type surgery. We investigated of, characteristics risk factors for 1-2 years shoulder replacement.A questionnaire was sent patients who underwent primary replacement between April 2011 2012, whose data were recorded in Danish Shoulder Arthroplasty Register. Patients had...
Atypical odontalgia (AO) is an intraoral pain condition of currently unknown mechanisms. In 10 AO patients and matched healthy controls, we examined the effect intravenous infusion N-methyl-d-aspartate (NMDA) receptor antagonist S-ketamine a μ-opioid agonist fentanyl on spontaneous acute nociceptive input evoked by topical application capsaicin. The drugs were administered in randomized, placebo-controlled, cross-over manner. Furthermore, measures sensitivity to mechanical thermal...
Background The presence of neutrophils among epithelial cells is one the major features inflammation in Crohn's disease, and has been used to indicate disease activity. survival outside blood vessels limited their longevity influenced by granulocyte–macrophage colony-stimulating factor (GM-CSF), which probably reduces neutrophil apoptosis. Objective To study GM-CSF production intestinal cell cultures from patients before after infliximab treatment. Patients Colonic mucosal biopsies were...
INTRODUCTION Surgical treatment of colorectal cancer carries a risk for venous thromboembolism (VTE). We investigated changes in coagulation and fibrinolysis the VTE incidence within 30 days patients undergoing open cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS+HIPEC) peritoneal metastases from minimally invasive (MIS) localized rectal cancer. METHODS This cohort study included 45 CRS+HIPEC MIS patients. Blood samples were obtained preoperatively, at end surgery,...
Acute and persistent pain after surgery is well described. However, no large-scale studies on immediate postoperative in the operating room (OR) exist, hindering potential areas of research to improve clinical outcomes. Thus, we aimed describe occurrence severity a large, unselected cohort.This was prospective cohort study, encompassing all procedures 31 public hospitals Danish Realm, during 5-day period including weekend. Data anesthesia were collected main outcome moderate or severe OR....
Pelvic pain is a primary symptom of women referred for hysterectomy. This study identified risk factors purchase prescribed analgesics before and after hysterectomy examined changes hysterectomy, specifically focusing on socioeconomic effects.Nearly all Danish (n=13,420) with benign indication between 2004 2006 were included in registry-based follow-up study. Information prescription analgesic was from the National Prescription Registry. Factors associated associations assessed.Analgesic...
Abstract Objectives Cancer cells can activate coagulation and inhibit fibrinolysis. The aim was to investigate the association between burden of peritoneal metastases from colorectal cancer (PM-CRC) biomarkers reflecting thrombin generation Methods A cohort 55 patients with PM-CRC scheduled for cytoreductive surgery. Patients were grouped by index (PCI) assessed intraoperatively into limited (PCI≤15) extensive (PCI>15). Blood samples obtained before Thrombin measured in vivo...
Abstract Pulse pressure variation (PPV) is a well-established method for predicting fluid responsiveness in mechanically ventilated patients. The predictive accuracy is, however, disputed ventilation with low tidal volume (V T ) or heart-rate-to-respiratory-rate ratio (HR/RR). We investigated the effects of V and RR on PPV PPV’s ability to predict responsiveness. included patients scheduled open abdominal surgery. Prior 250 ml bolus, we combinations from 4 10 kg −1 31 min . For each RR-V...