A5031334563- Hemodynamic Monitoring and Therapy
- Non-Invasive Vital Sign Monitoring
- Heart Rate Variability and Autonomic Control
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Ultrasound in Clinical Applications
- Cardiac Arrest and Resuscitation
- Machine Learning in Healthcare
- Cardiovascular Syncope and Autonomic Disorders
- COVID-19 Clinical Research Studies
- Artificial Intelligence in Healthcare and Education
- Renal function and acid-base balance
- Healthcare Technology and Patient Monitoring
- Pulmonary Hypertension Research and Treatments
- Mechanical Circulatory Support Devices
- SARS-CoV-2 and COVID-19 Research
- Opioid Use Disorder Treatment
- Diagnosis and Treatment of Venous Diseases
- Pain Management and Opioid Use
- Biomedical Text Mining and Ontologies
- Electrical and Bioimpedance Tomography
- Acute Myocardial Infarction Research
- COVID-19 and Mental Health
Aarhus University Hospital
2013-2024
Aarhus University
2014-2024
University College London
2022
Massachusetts Institute of Technology
2022
University of Groningen
2017-2020
Aalborg University Hospital
2009-2020
University Medical Center Groningen
2017-2020
North Denmark Region
2009
Aalborg University
2009
Intraoperative hypotension is associated with worse perioperative outcomes for patients undergoing major noncardiac surgery. The Hypotension Prediction Index a unitless number that derived from an arterial pressure waveform trace, and as the increases, risk of occurring in near future increases. We investigated diagnostic ability predicting impending intraoperative comparison to other commonly collected hemodynamic variables.
Vasopressors are commonly applied to restore and maintain blood pressure in patients with sepsis. We aimed evaluate the current practice therapeutic goals regarding vasopressor use septic shock as a basis for future studies provide some recommendations on their use. From November 2016 April 2017, an anonymous web-based survey of vasoactive drugs was accessible members European Society Intensive Care Medicine (ESICM). A total 17 questions focused profile respondents, triggering factors, first...
Treatment decisions on critically ill patients with circulatory shock lack consensus. In an international survey, we aimed to evaluate the indications, current practice, and therapeutic goals of inotrope therapy in treatment shock.
The Hypotension Prediction Index is a proprietary prediction model incorporated into commercially available intraoperative hemodynamic monitoring system. uses multiple features of the arterial blood pressure waveform to predict hypotension. index publication introducing describes selection training and validation data. Although precise details algorithm are proprietary, authors describe process whereby mean (MAP) less than 75 mmHg will always We hypothesize that data introduced systematic...
We present the INSPIRE dataset, a publicly available research dataset in perioperative medicine, which includes approximately 130,000 surgical operations at an academic institution South Korea over ten-year period between 2011 and 2020. This comprehensive patient characteristics such as age, sex, American Society of Anesthesiologists physical status classification, diagnosis, procedure code, department, type anaesthesia. The also vital signs operating theatre, general wards, intensive care...
Single-center, investigator-initiated, prospective cohort study.This study aimed to determine patient-reported reasons for persistent opioid use following elective spine surgery, assess the frequency of withdrawal symptoms, and characterize pain-related care sought after discharge.Patients are often prescribed opioids at discharge from hospital surgery. Several studies have shown that a large number patients fail discontinue treatment even months years Spine surgery has proven be high-risk...
The Hypotension Prediction Index (HPI) algorithm is a commercial prediction developed to predict hypotension, mean arterial pressure (MAP) below 65 mmHg. Although HPI has been investigated in several studies, recent concerns of have raised regarding HPI's predictive abilities, which may overstated. A selection bias forced the learn almost exclusively from MAP. This CON position paper describes further and summarises scientific status including meaning erratum retracting primary conclusion...
To examine the impact of ACE inhibitor (ACE-I)/angiotensin receptor blocker (ARB) use on rate SARS-CoV-2 infection and adverse outcomes. This nationwide case-control cohort study included all individuals in Denmark tested for RNA with PCR from 27 February 2020 to 26 July 2020. We estimated confounder-adjusted ORs a positive test among tested, inverse probability treatment weighted 30-day risk ratios (RRs) hospitalisation, intensive care unit (ICU) admission mortality comparing current...
The respiratory variation in the pre-ejection period (Delta PEP) has been used to predict fluid responsiveness mechanically ventilated patients. Recently, we modified this parameter (PEPV) and showed that it was a reliable predictor for post-cardiac surgery, mainly paced, patients when moderately low tidal volumes were used. One of modifications involved volume indexation, which had not proposed before dynamic parameters. aim present animal study investigate whether indexation should be part...
Reliable continuous monitoring of fluid responsiveness is an unsolved issue in patients ventilated with low tidal volume. We hypothesised that variations the pre-ejection period (PEP) defined as time interval between electrocardiogram (ECG) R-wave and onset systolic upstroke arterial blood pressure could reliably predict moderately Furthermore, we indexing dynamic parameters to volume would improve their prediction. The aim was refine automate a previously suggested algorithm for PEP...
Introduction: Acquired brain injury (ABI) cause neural deficits. In addition to motor and cognitive deficits, the autonomic nervous system may be affected. This has been shown for neurorehabilitation patients with traumatic (TBI) by means of reduced heart rate variability (HRV). It was hypothesized that patient groups other ABI aetiology (mainly stroke, subarachnoid haemorrhage anoxia) would also present HRV.Methods: Patients consecutively admitted severely injured were considered HRV...
To systematically evaluate the effect of small changes in transducer position on key hemodynamic variables including CO generated by 4th generation FloTrac software. After cardiac surgery, output, mean arterial pressure, systemic vascular resistance, and stroke volume variation were measured with 4 Flotrac The was randomly placed at midaxillary plane, cm higher than plane or lower plane. Averages three measurements used. Data available from 20 patients. Cardiac output increased 4.59 L/min (±...
Fluid responsiveness prediction with continuously available monitoring is an unsettled matter for the vast majority of critically ill patients, and development new reliable methods desired. We hypothesized that post-ectopic beat, which associated increased preload, could be analyzed in relation to preceding sinus beats change cardiac performance (e.g., systolic blood pressure) at beat predict fluid responsiveness. Critically patients were observed when scheduled a 500-ml volume expansion....