A5080976736- Cardiac electrophysiology and arrhythmias
- Neuroscience and Neural Engineering
- ECG Monitoring and Analysis
- Phonocardiography and Auscultation Techniques
- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Ion channel regulation and function
- Transcranial Magnetic Stimulation Studies
- Pain Management and Treatment
- Vagus Nerve Stimulation Research
- Cardiac Arrhythmias and Treatments
- Tactile and Sensory Interactions
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Musculoskeletal pain and rehabilitation
- Advanced Sensor and Energy Harvesting Materials
- Atrial Fibrillation Management and Outcomes
- Hemodynamic Monitoring and Therapy
- Cardiac Imaging and Diagnostics
- Conducting polymers and applications
- Receptor Mechanisms and Signaling
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
Aalborg University
2015-2025
Faculty (United Kingdom)
2019
Rigshospitalet
2013
University of Copenhagen
2013
Dansk Selskab for Anæstesiologi og Intensiv Medicin (Denmark)
2011
University of Twente
1988-2005
University of Strathclyde
2005
Universidade Federal Fluminense
2003
Digital stethoscopes offer new opportunities for computerized analysis of heart sounds. Segmentation sound recordings into periods related to the first and second (S1 S2) is fundamental in process. However, segmentation sounds recorded with handheld clinical environments often complicated by background noise. A duration-dependent hidden Markov model (DHMM) proposed robust The DHMM identifies most likely sequence physiological sounds, based on duration events, amplitude signal envelope a...
In epidural spinal cord stimulation it is likely not only that dorsal column fibers are activated, but also root will be involved as well. this investigation a volume conductor model of the was used and were modeled by an electrical network including fiber excitation. The effects varying some geometric characteristics, well influence cerebrospinal fluid layer electrode configuration on threshold stimulus for their excitation, assessed. values compared with those fibers. results modeling...
Using a large, contemporary primary care population we aimed to provide absolute long-term risks of cardiovascular death (CVD) based on the QTc interval and test whether is value in risk prediction CVD an individual level. Digital electrocardiograms from 173 529 patients aged 50–90 years were collected during 2001–11. The Framingham formula was used for heart rate-correction QT interval. Data medication, comorbidity, outcomes retrieved administrative registries. During median follow-up...
Earlier studies have documented that coronary artery disease (CAD) produces weak murmurs, which might be detected through analysis of heart sounds. An electronic stethoscope with a digital signal processing unit could low cost and easily applied method for diagnosis CAD. The current study is search sound features identify CAD.Nine different types from five overlapping frequency bands were obtained analyzed using 435 recordings 133 subjects.New describing an increase in low-frequency power...
An electrical network model of myelinated dorsal column nerve fibers is presented. The effect simulation was investigated using both a homogeneous volume conductor and more realistic the spinal cord. important feature presence collaterals perpendicular to rostro-caudal fibers. It found that transmembrane potentials, due external monopolar stimulation, at node which collateral attached, significantly influenced by collateral. concluded excitation threshold blocking are decreased up 50%...
The purpose of this work is to define fiducial points in the seismocardiogram (SCG) and correlate them with physiological events identified ultrasound images. For 45 healthy subjects SCG electrocardiogram (ECG) were recorded simultaneously at rest. Immediately following ECG recordings images heart also obtained all a mean signal was calculated (peaks valleys) labeled same way across signals. Eight physiologic events, including valve openings closings, annotated from as well correlated those...
Cardiac time intervals are important hemodynamic indices and provide information about left ventricular performance. Phonocardiography (PCG), impedance cardiography (ICG), recently seismocardiography (SCG) have been unobtrusive methods of choice for detection cardiac potentials to be integrated into wearable devices. The main purpose this study was investigate the accuracy precision beat-to-beat extraction timings from PCG, ICG SCG recordings in comparison multimodal echocardiography...
The potential distributions produced in the spinal cord and surrounding tissues by dorsal epidural stimulation at midcervical, midthoracic, low thoracic levels were calculated with use of a volume conductor model. Stimulus thresholds myelinated column fibers root each level models which thickness cerebrospinal fluid (CSF) layer was varied. Calculated stimulus compared paresthesia obtained from measurements corresponding patients. influences CSF thickness, contact separation bipolar...
The perception threshold for epidural spinal cord stimulation in chronic pain management was analyzed on 3,923 testing data obtained from 136 implanted patients. initial areas of paresthesiae due to were recorded and reported as the map according location electrodes. Measurement dorsal thickness cerebrospinal fluid (CSF) layer 26 subjects using magnetic resonance imaging (MRI). results indicate that is a function level electrodes, mediolateral position canal contact separation electrode....
Cuff electrodes for recording of the electro-neurogram from peripheral nerves were introduced by Hoffer [1974] and Stein, et al. [1975]. The cuffs used to obtain higher signal amplitudes than previously possible, at least in chronic recordings, decrease pick-up noise, especially muscles. are relatively stable long-term but stability has never been quantified terms input-output relationships; i.e., responses repeatable stimuli over time. Moreover. relationship between nerve damage...
A nerve stimulation model has been developed, incorporating realistic cross-sectional geometries and conductivities. The potential field in the volume conductor was calculated numerically using variational method. Nerve fiber excitation described by of McNeal. Cross-sectional small monofascicular rat common peroneal multifascicular human deep were taken as sample geometries. Selective a fascicle theoretically analyzed for several electrode positions: outside nerve, connective tissue inside...
The effect of electrical stimulation with several electrode combinations on nerve fibers different orientations in the spinal cord was investigated by computing steady-state field potentials and activating functions. At first an infinite homogeneous model used while secondly its surrounding tissues were modeled as inhomogeneous anisotropic volume conductor. mediodorsal epidural calculated. It concluded that cathodal stimulation, mediodorsally space, longitudinal are depolarized, but...
The aim of this study was to investigate theoretically the conditions for activation detrusor muscle without urethral sphincter and afferent fibers, when stimulating related sacral roots, Therefore, sensitivity excitation blocking thresholds nerve fibers within a root geometric electrical parameters in tripolar stimulation using cuff electrode, have been simulated by computer model. A 3D rotationally symmetrical model, representing geometry conductivity surrounded cerebrospinal fluid used,...
Effects of both anatomic and electrode geometry on the recruitment rostrocaudal fibers in spinal cord were investigated by computer simulation epidural stimulation. A three-dimensional model was used, representing electrical conductivity surrounding tissues, combination with a properties myelinated nerve fiber. Recruitment contours dorsal columns calculated at various geometries as function position, area. Cathodal position appeared to be most significant. areas resulting from different...