A5067984418- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Central Venous Catheters and Hemodialysis
- Traumatic Brain Injury Research
- Intensive Care Unit Cognitive Disorders
- Blood Pressure and Hypertension Studies
- Cardiac electrophysiology and arrhythmias
- Potassium and Related Disorders
- Trauma Management and Diagnosis
- Anesthesia and Neurotoxicity Research
- COVID-19 Clinical Research Studies
- Airway Management and Intubation Techniques
- Poisoning and overdose treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Non-Invasive Vital Sign Monitoring
- Anesthesia and Pain Management
- Thermal Regulation in Medicine
- Animal testing and alternatives
- Long-Term Effects of COVID-19
- Disaster Response and Management
- Trauma and Emergency Care Studies
Aarhus University
2018-2025
Central Denmark Region
2020-2025
Aarhus University Hospital
2018-2024
Out-of-hospital cardiac arrest is a leading cause of death worldwide. Establishing vascular access critical for administering guideline-recommended drugs during cardiopulmonary resuscitation. Both the intraosseous route and intravenous are used routinely, but their comparative effectiveness remains unclear.
It is unclear whether administration of calcium has a beneficial effect in patients with cardiac arrest.To determine during out-of-hospital arrest improves return spontaneous circulation adults.This double-blind, placebo-controlled randomized clinical trial included 397 adult and was conducted the Central Denmark Region between January 20, 2020, April 15, 2021. The last 90-day follow-up on July 2021.The intervention consisted up to 2 intravenous or intraosseous doses 5 mmol chloride (n =...
Current international guidelines recommend administrating calcium chloride and sodium bicarbonate to patients with hyperkalemia-induced cardiac arrest, despite limited evidence. The aim of this study was evaluate the efficacy on return spontaneous circulation (ROSC) in a pig model arrest.
During cardiac arrest, current guidelines recommend attempting intravenous access first and to consider intraosseous if is unsuccessful or impossible. However, these recommendations are only based on very low-certainty evidence. Therefore, the "Intravenous vs Intraosseous Vascular Access Out-of-Hospital Cardiac Arrest" (IVIO) trial aims determine whether there a difference in patient outcomes depending type of vascular attempted during out-of-hospital arrest. This article describes clinical...
Fluid responsiveness prediction with continuously available monitoring is an unsettled matter for the vast majority of critically ill patients, and development new reliable methods desired. We hypothesized that post-ectopic beat, which associated increased preload, could be analyzed in relation to preceding sinus beats change cardiac performance (e.g., systolic blood pressure) at beat predict fluid responsiveness. Critically patients were observed when scheduled a 500-ml volume expansion....
The aim of the current study was to determine if treatment with senicapoc, improves PaO2 /FiO2 ratio in patients COVID-19 and severe respiratory insufficiency.Investigator-initiated, randomized, open-label, phase II trial four intensive care units (ICU) Denmark. We included aged ≥18 years admitted an ICU insufficiency due COVID-19. intervention consisted 50 mg enteral senicapoc administered as soon possible after randomization again 24 h. Patients control group received standard only....
Introduction: The Calcium for Out-of-hospital Cardiac Arrest (COCA)-trial recently found no benefit of administering calcium during out-of-hospital cardiac arrest in an unselected adult population. Still, is recommended caused by hyperkalemia. Higher potassium levels have been patients with wide QRS-complexes which may act as indicator Objectives: 1) To describe characteristics baseline PEA arrest, and 2) to determine the effect on return spontaneous circulation (ROSC) displaying normal...