A5031055158- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Blood Pressure and Hypertension Studies
- Sepsis Diagnosis and Treatment
- Cardiovascular Syncope and Autonomic Disorders
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Ultrasound in Clinical Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Respiratory Support and Mechanisms
- Healthcare Technology and Patient Monitoring
- Phonocardiography and Auscultation Techniques
- Machine Learning in Healthcare
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Health and Disease Prevention
- Renal function and acid-base balance
- Cardiovascular Function and Risk Factors
Aarhus University Hospital
2017-2023
Aarhus University
2018-2023
The Hypotension Prediction Index is a proprietary prediction model incorporated into commercially available intraoperative hemodynamic monitoring system. uses multiple features of the arterial blood pressure waveform to predict hypotension. index publication introducing describes selection training and validation data. Although precise details algorithm are proprietary, authors describe process whereby mean (MAP) less than 75 mmHg will always We hypothesize that data introduced systematic...
The Hypotension Prediction Index (HPI) algorithm is a commercial prediction developed to predict hypotension, mean arterial pressure (MAP) below 65 mmHg. Although HPI has been investigated in several studies, recent concerns of have raised regarding HPI's predictive abilities, which may overstated. A selection bias forced the learn almost exclusively from MAP. This CON position paper describes further and summarises scientific status including meaning erratum retracting primary conclusion...
Abstract Common physiological time series and waveforms are composed of repeating cardiac respiratory cycles. Often, the effect is primary interest, but for, e.g., fluid responsiveness prediction, on arterial blood pressure also convey important information. In either case, it relevant to disentangle two effects. Generalized additive models (GAMs) allow estimating predictors as nonlinear, smooth functions. These functions can represent cycles’ effects a signal. We demonstrate how GAMs...
Constipation is suspected to occur frequently after acquired brain injury (ABI). In patients with ABI, heart rate variability (HRV) reduced suggesting autonomic dysfunction. Autonomic dysfunction may be associated prolonged gastrointestinal transit time (GITT). The primary aim of this study was investigate if GITT in ABI. Secondarily, HRV and its correlation investigated.We included 25 ABI (18 men, median age: 61.3 years, range [30.7-74.5]). assessed using radio-opaque markers calculated...
Abstract Background Phenylephrine increases systemic‐ and pulmonary resistances therefore may increase blood pressures at the expense of flow. Cardio‐pulmonary bypass alters vasoreactivity many patients exhibit chronotropic insufficiency after cardiac surgery. We aimed to describe haemodynamic effects phenylephrine infusion Methods Patients in steady state low‐risk surgery received incremental rates up 1.0 μg/kg/min with aim increasing systemic mean arterial pressure 20 mmHg. Invasive...
Abstract Pulse pressure variation (PPV) is a well-established method for predicting fluid responsiveness in mechanically ventilated patients. The predictive accuracy is, however, disputed ventilation with low tidal volume (V T ) or heart-rate-to-respiratory-rate ratio (HR/RR). We investigated the effects of V and RR on PPV PPV’s ability to predict responsiveness. included patients scheduled open abdominal surgery. Prior 250 ml bolus, we combinations from 4 10 kg −1 31 min . For each RR-V...
Background . Extrasystoles may be useful for predicting the response to fluid therapy in hemodynamically unstable patients but their prevalence is unknown. The aim of this study was estimate availability extrasystoles intensive care unit diagnosed with sepsis. not validate responsiveness prediction ability extrasystoles. Methods Twenty-four-hour ECG recordings from a convenience sample 50 sepsis were extracted MIMIC-II waveform database, and ECGs visually examined correct QRS complex...