A5043938478- Colorectal Cancer Surgical Treatments
- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Screening and Detection
- Cancer survivorship and care
- Colorectal and Anal Carcinomas
- Diverticular Disease and Complications
- Gastrointestinal motility and disorders
- Nutrition and Health in Aging
- Health Systems, Economic Evaluations, Quality of Life
- Cancer-related cognitive impairment studies
- Urinary Bladder and Prostate Research
- Clinical practice guidelines implementation
- Congenital gastrointestinal and neural anomalies
- Gastric Cancer Management and Outcomes
- Delphi Technique in Research
- Hernia repair and management
- Tryptophan and brain disorders
- Stoma care and complications
- Inflammatory Bowel Disease
- Palliative Care and End-of-Life Issues
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical Sutures and Adhesives
- Diet and metabolism studies
- Advances in Oncology and Radiotherapy
Maastricht University Medical Centre
2016-2025
Maastricht University
2016-2025
University Medical Center
2012-2024
Karolinska University Hospital
2021
Netherlands Comprehensive Cancer Organisation
2021
University of Amsterdam
2019
Amsterdam University Medical Centers
2019
Massachusetts General Hospital
2018
Pontificia Universidad Católica de Chile
2018
Aarhus University Hospital
2018
The aim of this study was to establish the oncological and functional results organ preservation with a watch-and-wait approach (W&W) selective transanal endoscopic microsurgery (TEM) in patients clinical complete or near-complete response (cCR) after neoadjuvant chemoradiation for rectal cancer.Between 2004 2014, offered if assessment digital examination, endoscopy, MRI showed (near) cCR. Watch-and-wait cCR, two options were near cCR: TEM reassessment three months. Follow-up included...
The response to chemoradiotherapy (CRT) for rectal cancer can be assessed by clinical examination, consisting of digital examination (DRE) and endoscopy, MRI. A high accuracy is required select complete (CR) organ-preserving treatment. aim this study was evaluate the value (endoscopy with or without biopsy DRE), T2W-MRI, diffusion-weighted MRI (DWI) detection CR after CRT. This prospective cohort in a university hospital recruited 50 patients who underwent assessment (DRE, endoscopy biopsy),...
BACKGROUND: Fifteen to twenty percent of patients with locally advanced rectal cancer have a clinical complete response after chemoradiation therapy. These can be offered nonoperative organ-preserving treatment, the so-called watch-and-wait policy. The main goal this policy is an anticipated improved quality life and functional outcome in comparison total mesorectal excision, while maintaining good oncological outcome. OBJECTIVE: aim study was compare matched-controlled group who underwent...
Abstract Aim The goal of this European Society ColoProctology project was to establish a multidisciplinary, international guideline for haemorrhoidal disease (HD) and provide guidance on the most effective (surgical) treatment patients with HD. Methods development process consisted six phases. In phase one we defined scope guideline. patient population included all stages haemorrhoids. target group practitioners treating haemorrhoids and, in addition, healthcare workers who desired...
Importance A watch-and-wait approach for patients with rectal cancer and a clinical complete response after neoadjuvant chemoradiotherapy or radiotherapy is associated better quality of life functional outcome. Nevertheless, prospective data on both parameters are scarce. Objective To prospectively evaluate outcome, including bowel, urinary, sexual function, following approach. Design, Setting, Participants total 278 near-complete were included in 2 cohort studies: single-center study (March...
The goal of this project was to create an up-to-date joint European clinical practice guideline for the diagnosis and treatment faecal incontinence (FI), using best available evidence. These guidelines are intended help guide all medical professionals treating adult patients with FI (e.g., general practitioners, surgeons, gastroenterologists, other healthcare workers) any who interested in information regarding management FI.These have been created cooperation members from United...
Abstract Background In rectal cancer, watch and wait for patients with a cCR after neoadjuvant treatment has an established evidence base. However, there is lack of consensus on the definition management near-cCR. This study aimed to compare outcomes in who achieved at first reassessment versus later reassessment. Methods registry included from International Watch & Wait Database. Patients were categorized as having or (that near-cCR reassessment) based MRI endoscopy. Organ preservation,...
Background and Aims:In the past decades, treatment options strategies for ulcerative colitis [UC] have radically changed. Whether these developments altered disease outcome at population level is yet unknown. Therefore, we evaluated of UC over two decades in South-Limburg area The Netherlands.
Abstract Aim The primary aim of the European Society Coloproctology (ESCP) Guideline Development Group (GDG) was to produce high‐quality, evidence‐based guidelines for management cryptoglandular anal fistula with input from a multidisciplinary group and using transparent, reproducible methodology. Methods Previously published methodology in guideline development by ESCP has been replicated this project. process followed requirements AGREE‐S tool kit. Six phases can be identified Phase one...
Purpose Next to surgical margins, yield of lymph nodes, and length bowel resected, macroscopic completeness mesorectal excision may serve as another quality control total (TME). In this study, the laparoscopic TME was evaluated. Methodology A series 25 patients with rectal cancer were managed laparoscopically (LTME) included in study. The pathologic specimens LTME group prospectively examined matched a historical resection from who had undergone open (OTME). two groups for gender type (low...
Restorative proctocolectomy with IPAA is an optimal surgical treatment for patients familial adenomatous polyposis and therapy resistant ulcerative colitis, few data are available on long-term results in who have undergone this operation at a young age.The aim of study was to investigate functional outcome, quality life, body image, sexual function after restorative or colitis.The consisted retrospective review medical records questionnaire follow-up 26 consecutive colitis had surgery...
Functional constipation in children and adolescents is a common invalidating condition. In minority of patients, symptoms persist despite optimal conservative therapy. The aim this study was to evaluate whether the short-term effects sacral neuromodulation (SNM) with are sustained over prolonged period time.Patients aged 10-20 years, refractory constipation, fulfilling Rome III criteria, were included our study. If SNM test treatment showed >50 % improvement defecation frequency, permanent...