A5085080215- Chronic Kidney Disease and Diabetes
- Renal Transplantation Outcomes and Treatments
- Renal Diseases and Glomerulopathies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet, Metabolism, and Disease
- Organ Donation and Transplantation
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Function and Risk Factors
- Male Reproductive Health Studies
- Birth, Development, and Health
- Diet and metabolism studies
- Organ Transplantation Techniques and Outcomes
- Metabolism and Genetic Disorders
- Dialysis and Renal Disease Management
- Phytochemicals and Antioxidant Activities
- Genomics, phytochemicals, and oxidative stress
- Sodium Intake and Health
- Viral-associated cancers and disorders
- Blood Pressure and Hypertension Studies
- Food Science and Nutritional Studies
- Polyomavirus and related diseases
- Neurological Complications and Syndromes
- Colorectal and Anal Carcinomas
- Nanoparticle-Based Drug Delivery
- Celiac Disease Research and Management
Champalimaud Foundation
2025
Polytechnic Institute of Coimbra
2019-2024
University of Coimbra
2020-2024
CUF Porto Hospital
2023
Hospital Dr. Nélio Mendonça
2013-2023
Karolinska Institutet
2023
Centro Hospitalar do Porto
2015-2016
Fundação Universitária de Cardiologia
2012-2014
Universidade de São Paulo
2011
Abstract Background In rectal cancer, watch and wait for patients with a cCR after neoadjuvant treatment has an established evidence base. However, there is lack of consensus on the definition management near-cCR. This study aimed to compare outcomes in who achieved at first reassessment versus later reassessment. Methods registry included from International Watch & Wait Database. Patients were categorized as having or (that near-cCR reassessment) based MRI endoscopy. Organ preservation,...
Blueberries, red fruits enriched in polyphenols and fibers, are envisaged as a promising nutraceutical intervention plethora of metabolic diseases. Prediabetes, an intermediate state between normal glucose tolerance type 2 diabetes, fuels the development complications, including hepatic steatosis. In previous work, we have demonstrated that blueberry juice (BJ) supplementation benefits glycemic control lipid profile, which was accompanied by amelioration mitochondrial bioenergetics. The...
Minimally invasive surgery has become the gold standard for colorectal cancer treatment. Approximately 40% of patients undergoing elective resection develop postoperative complications. The median time to clinical diagnosis a complication ranges between 5 and 8 days. Early detection complications can reduce their morbidity negative impact. This study aims evaluate effectiveness routine inflammatory markers in predicting early minimally cancer. was conducted at single center is retrospective...
The inflammatory pathway driven by TNF-α, through its receptors TNFR1 and TNFR2, is a common feature in the pathogenesis of chronic kidney disease (CKD), regardless initial cause. Evidence correlates status with decreased renal function. Our aim was to evaluate potential TNF as biomarkers for CKD diagnosis staging, well their association progression lesions, rat models early moderate CKD. We analyzed circulating levels molecules—tumor necrosis factor-alpha (TNF-α), tumor factor receptor 1...
The association between high-sensitivity C-reactive protein and recurrent major adverse cardiovascular events (MACE) in patients with ST-elevation myocardial infarction who undergo primary percutaneous coronary intervention remains controversial.To investigate the potential an increased risk of MACE such as death, heart failure, reinfarction, new revascularization treated intervention.This prospective cohort study included 300 individuals aged >18 years were diagnosed underwent at a tertiary...
Diabetic nephropathy (DN) is a major microvascular complication of diabetes. Obesity and hyperlipidemia, fueled by unhealthy food habits, are risk factors to glomerular filtration rate (GFR) decline DN progression. Several studies recommend that diabetic patients should be screened early (in prediabetes) for kidney disease, in order prevent advanced stages, whom the current interventions clearly inefficient. This ambition greatly depends on existence accurate biomarkers novel molecular...
FUNDAMENTO: O exame da glicose plasmática de jejum (GPJ) é preditor complicações após Síndrome Coronariana Aguda (SCA). No entanto, seu valor prognóstico ainda não está plenamente estabelecido em diferentes faixas etárias. OBJETIVO: Avaliar o papel como evolução, 30 dias a SCA, e comparar associação hiperglicemia com eventos cardiovasculares maiores (ECM): óbito, reinfarto revascularização, dois grupos etários (<65 anos > 65 idade). MÉTODOS: Coorte contemporânea pacientes hospitalizados por...
Cosmetic products have been increasingly regulated, particularly in Europe. With the introduction of cosmetic regulation 2013, stricter quality standards were implemented, surpassing those set by 1976 legislation. The primary objective these regulations is to safeguard consumer safety during use products. Despite advancements, certain regulatory gaps remain, indicating need for more effective measures enhance human and environmental health protection. Considering aforementioned, this work...
Membranous nephropathy is the most common cause of nephrotic syndrome in adults. A non-negligible number cases are associated with systemic conditions. We report a case 50-year-old man who presented six months after being diagnosed celiac disease. Although patient showed disappearance circulating immunoglobulin (IgA) anti-tissue transglutaminase antibodies following gluten-free diet, he had sudden onset presenting severe hypoalbuminemia. Other secondary causes were promptly excluded leading...