A5033014191- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Renal and Vascular Pathologies
- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Transplantation: Methods and Outcomes
- Organ and Tissue Transplantation Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pancreatic function and diabetes
- COVID-19 Clinical Research Studies
- Blood groups and transfusion
- Neurological Complications and Syndromes
- Diabetes Treatment and Management
- COVID-19 Impact on Reproduction
- Hepatitis C virus research
- Diabetes and associated disorders
- Liver Disease and Transplantation
- Complement system in diseases
- Pregnancy and Medication Impact
- Systemic Sclerosis and Related Diseases
- Blood Pressure and Hypertension Studies
- Cell Adhesion Molecules Research
- COVID-19 and healthcare impacts
Universidade do Porto
2015-2025
Hospital de Santo António
2015-2025
National Statistical Institute of Portugal
2023-2024
Centro Hospitalar do Porto
2014-2023
CUF Porto Hospital
2022-2023
Institute of Biomedical Science
2022-2023
Translational Research in Oncology
2022-2023
Hospital Braga
2022-2023
Centro Hospitalar de Trás os Montes e Alto Douro
2022-2023
Centro Hospitalar Tondela-Viseu
2022
Kidney transplant (KT) recipients have a high risk for adverse outcomes from infections, such as COVID-19.We retrospectively reviewed all KT with documented COVID-19 between March 1, 2020, and 15, 2021, analyzed patients' characteristics, clinical course, treatment, outcomes.We identified 123 patients, 72% were male, mean age of 54.5±13.0 years. Twenty percent asymptomatic, 7% had nosocomial transmission, 36% the remainder required hospitalization. Almost admitted patients received oxygen,...
A doença renal crónica representa um problema de saúde pública significativo, afetando cerca 9,8% da população adulta em Portugal. Pese embora este número, o diagnóstico precoce desta nos grupos alto risco é reduzido. Apesar serem apenas dois os parâmetros cruciais para seu – a taxa filtração glomerular estimada (TFGe) e albuminúria Portugal, mais 50% dos doentes estádio 3 - 5 não foram alvo avaliação concomitante TFGe albuminúria. falta implementação destas duas métricas simultâneo, leva à...
Evaluation of the impact liver transplantation in natural history ocular disorders familial amyloidotic polyneuropathy (FAP) amyloidosis TTR V30M related (ATTR V30M) patients.A clinical, retrospective and cross-sectional study 64 Portuguese FAP ATTR patients was carried out between January 2005 December 2011.Thirty-two transplanted (both eyes) aged 39.6-53.8 years old, 32/32 male/female, were paired with an equal number non-transplanted patients, matching for age, gender, age at onset,...
Abstract Steal syndrome is a feared complication of dialysis vascular access in population becoming older and frailer. The aim this study was to determine the predictor factors steal syndrome. All proximal arteriovenous fistulas ( AVFs ), patent at day 30, inserted between J anuary 2008 D ecember 2009 were studied. Data on age, gender, diabetes mellitus DM ) status, presence coronary or peripheral artery disease, date initiation renal replacement therapy, construction, localization, type...
Pancreas-kidney transplantation (PKT) may significantly improve quality of life (HRQOL) in patients with type 1 diabetes. We have assessed the changes felt by PKT patients, using Gastrointestinal Quality Life Index (GIQLI) and EuroQol-5D questionnaires. Patients were asked to compare how their HRQOL had changed from pre-transplantation last visit. The 60 men 66 women enrolled a mean follow-up five yr; 84.1% both grafts, 15.9% one graft functioning. In all domains scores improved after PKT,...
<b><i>Aim:</i></b> Mortality in end-stage renal disease (ESRD) remains high, particularly among elderly, who represents the most rapidly growing segment of ESRD population wealthier countries. We developed and validated a risk score elderly patients to predict 6-month mortality after dialysis initiation. <b><i>Methods:</i></b> used data from cohort 421 patients, aged 65 years over started between 2009 2016, our Nephrology department. The...
Abstract Simultaneous pancreas‐kidney transplantation (SPKT) is the best treatment for selected individuals with type 1 diabetes mellitus and end‐stage renal disease. Despite advances in surgical techniques, donor recipient selection, immunosuppressive therapies, SPKT remains a complex procedure associated complications adverse consequences. We conducted retrospective study that included 263 procedures performed between May 2000, December 2022. A total of 65 patients (25%) required at least...
Abstract Background and Aims Alport syndrome (AS) is the most common cause of inherited chronic kidney disease. This disorder caused by deleterious variants on COL4A3, COL4A4 or COL4A5 genes. These genes codify proteins that constitute collagen type IV glomerular basement membrane (GBM). Alterations in any constituents disruption GMB structure, allowing leakage red blood cells proteins, mainly albumin, into urine resulting damage loss renal function. In AS progressive impairment can be...
Both donor-specific antibodies (DSA) and anti-angiotensin II type 1 receptor (AT1R-abs) have been associated with poor graft outcomes after kidney transplantation (KT). We aimed to understand the impact of pretransplant AT1R-abs or without concomitant DSA on KT outcomes.Seventy-six patients transplanted in 2009 were studied. (MFI > 1000) and/or (>10UI) detected by solid-phase assays pre-KT sera. Multivariable Cox regression models used determine independent predictors outcomes: acute...
Abstract HLA donor‐specific antibodies developed de novo after transplant remain a major cause of chronic allograft dysfunction. Our study main purpose was to determine whether MM, assessed traditionally and by total AbVer eplet mismatch load (EptMM EpvMM) with HLAMatchMaker, had impact on dn DSA development living donor kidney transplantation (LDKT). We retrospectively analysed cohort 96 LDKT between 2008 2017 performed in Hospital Santo António. Seven patients DSA‐II EpvMM EptMM were...