A5071659851- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Maternal and fetal healthcare
- Reproductive System and Pregnancy
- Systemic Lupus Erythematosus Research
- Cannabis and Cannabinoid Research
- Neonatal Respiratory Health Research
- Birth, Development, and Health
- Congenital Diaphragmatic Hernia Studies
- Neurological Complications and Syndromes
- Prenatal Screening and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Gestational Diabetes Research and Management
- Maternal and Perinatal Health Interventions
- Ectopic Pregnancy Diagnosis and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Blood Coagulation and Thrombosis Mechanisms
- Mobile Health and mHealth Applications
- Pregnancy-related medical research
- Neuroscience of respiration and sleep
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Pituitary Gland Disorders and Treatments
- Cancer Risks and Factors
- Prenatal Substance Exposure Effects
Centro Hospitalar do Porto
2015-2024
Universidade do Porto
2017-2022
Centro Hospitalar do Baixo Vouga
2019-2020
Universidade Federal do Pará
2020
Institute Of Perinatology Obstetrics And Gynaecology
2019
CUF Porto Hospital
2018
Research Network (United States)
2016
Institute of Biomedical Science
2014
Hospital de Santo António
1996-2011
ACTA (United States)
1997
Cannabis use has become a hot topic in several countries due to the debate about its legalization for medical purposes. However, data are limited regarding adverse events, safety and potential impact on reproductive health. consumption during pregnancy been associated with gestational disorders such as preterm birth, intrauterine growth restriction, low birth weight increased risk of miscarriage, though underlying biochemical mechanisms still unknown. Given that endocannabinoid system (ECS)...
O município de Parintins apresenta deficiências significativas em seu sistema drenagem urbana, especialmente durante o período chuvas intensas, característico da região amazônica. A infraestrutura atual demonstra-se inadequada para manejar volume águas pluviais, resultando alagamentos frequentes e inundações vias residências, com consequências adversas a saúde bem-estar população. Este estudo caso foca na Rua Balbino Noronha, no Bairro Emílio Moreira, onde ausência um eficiente resulta...
A pesquisa analisa o impacto da evangelização sobre as práticas religiosas e os sistemas de crenças dos povos indígenas, evidenciando apagamento rituais mitologias ancestrais. O avanço das missões evangélicas promove uma reconfiguração identidades frequentemente associada à negação elementos culturais tradicionais. Esse fenômeno reflete um processo colonização simbólica, no qual a religiosidade cristã se impõe como única via legítima fé. Dito isso, estudo discute tensões entre tradição...
What are the effects of endocannabinoid anandamide (AEA) in uterine natural killer (unK) cells from miscarriage decidua, regarding their cytokine profile and endometrial stromal cell (ESC) crosstalk?uNK-conditioned media samples present high TNF-α levels which inhibit ESC decidualisation.AEA plasma higher women who have suffered a miscarriage. Moreover, AEA inhibits proliferation differentiation, although impact on uNK at feto-maternal interface remain elusive.This laboratory-based study...
Introduction: We evaluated the clinical course during pregnancy and neonatal outcomes of a cohort Portuguese women with myasthenia gravis (MG). Methods: Retrospective study. Results: Twenty-five patients 30 pregnancies were included. Mean maternal age was 32.4 ± 4.1 years. Miscarriage rate 6.7%, delivery 28 newborns. Deterioration in MG occurred 43.3%, 46.4% at postpartum. Eighty percent medicated pyridostigmine, 43.3% corticosteroids, 40% intravenous immunoglobulin. There no or deaths....
Systemic lupus erythematosus (SLE) is a life-threatening disorder that affects women at reproductive age. We evaluate the clinical impact of pregnancy in cohort Portuguese SLE patients and risk factors associated with maternal fetal adverse outcomes.A retrospective observational study included all pregnant managed tertiary hospital, between January 1993 December 2019. Baseline information was collected, maternal-fetal neonatal outcomes were evaluated. Disease activity before during...
Background. The use of human recombinant erythropoietin (rHuEPO) in pregnant patients has been limited by the fear eventual maternal and fetal repercussions (either direct or indirect). Methods. authors present their experience with rHuEPO during pregnancy, two women kidney transplants three others chronic renal insufficiency (one diabetic nephropathy, another dialysis dependent), all hematocrit below 30% adequate iron reserves. Results. Three had needed blood transfusions before beginning...
Proliferation, differentiation and apoptosis of trophoblast cells are required for normal placental development. Impairment those processes may lead to pregnancy-related diseases. Disruption endoplasmic reticulum (ER) homeostasis has been associated with several reproductive pathologies including recurrent pregnancy loss preeclampsia. In the unfolded protein response (UPR), specific ER-stress signalling pathways activated restore ER homeostasis, but if adaptive fails, is triggered. Protein...
Cannabis consumption is increasing worldwide either for recreational or medical purposes. Its use during gestation associated with negative pregnancy outcomes such as, intrauterine growth restriction, preterm birth, low birth weight, and increased risk of miscarriage, though the underlying molecular mechanisms are unknown. sativa main psychoactive compound, Δ9-tetrahydrocannabinol (THC) highly lipophilic, as such, readily crosses placenta. Consequently, THC may alter normal placental...
The objective of this article is to evaluate the impact pregnancy in women with prolactinoma, possible consequences therapy maintenance/discontinuation during and assess type delivery maternal-foetal obstetrical outcome. A retrospective study all pregnant prolactinoma our Centre between 2006 2014 was made. We had 35 cases two which an episode pituitary apoplexy second trimester. At time conception, most were being treated 5 mg bromocriptine. majority suspended medication 8th week gestation....
Preeclampsia (PE), a leading cause of maternal and perinatal morbidity mortality worldwide, is hypertensive disorder unknown aetiology characterized by proteinuria, coagulation abnormalities different systemic manifestations. Since there are no studies regarding the evaluation oxidized LDL (oxLDL) in women with history PE, we focused on lipid profile oxLDL plasma concentration several years after pregnancy to see if these have any modifications parameters that may be linked risk...